The Importance of Marine Omega-3s for Brain Development and the Prevention and Treatment of Behavior, Mood, and Other Brain Disorders

Nutrients. 2020 Aug 4;12(8):2333. doi: 10.3390/nu12082333.

Abstract

Most of the global population is deficient in long-chain marine omega-3s. In particular, docosahexaenoic acid (DHA), a long-chain omega-3 fatty acid, is important for brain and eye development. Additionally, DHA plays a significant role in mental health throughout early childhood and even into adulthood. In the brain, DHA is important for cellular membrane fluidity, function and neurotransmitter release. Evidence indicates that a low intake of marine omega-3s increases the risk for numerous mental health issues, including Attention Deficit Hyperactivity Disorder (ADHD), autism, bipolar disorder, depression and suicidal ideation. Studies giving supplemental marine omega-3s have shown promise for improving numerous mental health conditions. This paper will review the evidence surrounding marine omega-3s and mental health conditions.

Keywords: attention; brain; depression; fish oil; mood; omega-3.

Publication types

  • Review

MeSH terms

  • Adult
  • Attention Deficit Disorder with Hyperactivity / prevention & control
  • Attention Deficit Disorder with Hyperactivity / therapy
  • Brain / growth & development
  • Brain Diseases / prevention & control
  • Brain Diseases / therapy
  • Child
  • Dietary Supplements*
  • Docosahexaenoic Acids / pharmacology*
  • Humans
  • Mental Disorders / etiology
  • Mental Disorders / prevention & control*
  • Mental Disorders / therapy*
  • Mood Disorders / prevention & control
  • Mood Disorders / therapy
  • Neurodevelopmental Disorders / prevention & control
  • Neurodevelopmental Disorders / therapy
  • Seafood / analysis*

Substances

  • Docosahexaenoic Acids