Exclusion Diets in Functional Dyspepsia

Nutrients. 2022 May 14;14(10):2057. doi: 10.3390/nu14102057.

Abstract

Functional dyspepsia represents one of the most common and prevalent disorders of the brain-gut interaction, with a large number of widespread risk factors being identified. With an intricate pathogenesis and symptomatology, it heavily impacts the quality of life and, due to the limited efficacy of traditional pharmacological agents, patients are likely to seek other medical and non-medical solutions to their problem. Over the last few years, significant research in this domain has emphasized the importance of various psychological therapies and nutritional recommendations. Nevertheless, a correlation has been established between functional dyspepsia and food intolerances, with more and more patients adopting different kinds of exclusion diets, leading to weight loss, restrictive eating behaviour and an imbalanced nutritional state, further negatively impacting their quality of life. Thus, in this systematic review, we aimed at analysing the impact and efficiency of certain exclusion diets undertook by patients, more precisely, the gluten-free diet and the low-FODMAP diet.

Keywords: FODMAPs; diet; disorders of the brain–gut interaction; functional dyspepsia; functional gastrointestinal disorders.

Publication types

  • Systematic Review

MeSH terms

  • Diet Therapy*
  • Diet, Carbohydrate-Restricted
  • Diet, Gluten-Free
  • Dyspepsia*
  • Food Intolerance
  • Humans
  • Quality of Life

Grants and funding

This research received no external funding.