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    MAP3K2 mitogen-activated protein kinase kinase kinase 2 [ Delphinapterus leucas (beluga whale) ]

    Gene ID: 111183352, updated on 15-Mar-2024

    Summary

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    Gene symbol
    MAP3K2
    Gene description
    mitogen-activated protein kinase kinase kinase 2
    See related
    Ensembl:ENSDLEG00000014605
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Delphinapterus leucas
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Monodontidae; Delphinapterus
    Orthologs
    human mouse all
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    Genomic context

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    See MAP3K2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    101 current ASM228892v3 (GCF_002288925.2) Unplaced Scaffold NW_022097997.1 (4208275..4304891)
    100 previous assembly ASM228892v2 (GCF_002288925.1) Unplaced Scaffold NW_019160898.1 (4209125..4305325)

    NW_022097997.1Genomic Context describing neighboring genes Neighboring gene interacts with SUPT6H, CTD assembly factor 1 Neighboring gene protein C, inactivator of coagulation factors Va and VIIIa Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene ERCC excision repair 3, TFIIH core complex helicase subunit Neighboring gene cytochrome P450 27C1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitogen-activated protein kinase kinase kinase 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Delphinapterus leucas Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM228892v3 Primary Assembly

    Genomic

    1. NW_022097997.1 Reference ASM228892v3 Primary Assembly

      Range
      4208275..4304891
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022590566.2 → XP_022446274.1  mitogen-activated protein kinase kinase kinase 2

      UniProtKB/TrEMBL
      A0A2Y9PH65
      Related
      ENSDLEP00000020038.1, ENSDLET00000022087.1
      Conserved Domains (2) summary
      cd06405
      Location:45 → 123
      PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
      cd06652
      Location:354 → 617
      STKc_MEKK2; Catalytic domain of the Serine/Threonine Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 2
    Nucleotide Protein
    Heading Accession and Version

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