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    Or67b Odorant receptor 67b [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39120, updated on 10-May-2024

    Summary

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    Official Symbol
    Or67bprovided by FlyBase
    Official Full Name
    Odorant receptor 67bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036019
    Locus tag
    Dmel_CG14176
    See related
    AllianceGenome:FB:FBgn0036019
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    67b; 67B.2; CG14176; Dmel\CG14176; DmOr67b; OR67b
    Summary
    Predicted to enable odorant binding activity and olfactory receptor activity. Involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in dendrite membrane. Predicted to be active in plasma membrane. Predicted to be integral component of membrane. Is expressed in antennal segment and olfactory system. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

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    See Or67b in Genome Data Viewer
    Location:
    67C2-67C2; 3-31 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (9627316..9629193, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (9620416..9622293, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Transmembrane channel-like Neighboring gene uncharacterized protein Neighboring gene Laminin B2 Neighboring gene uncharacterized protein Neighboring gene Cyclophilin 40 Neighboring gene furry Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolution of Olfactory Receptors Tuned to Mustard Oils in Herbivorous Drosophilidae. Matsunaga T, et al. Mol Biol Evol, 2022 Feb 3. PMID 34963012, Free PMC Article
    2. Comparative chemosensation from receptors to ecology. Bargmann CI. Nature, 2006 Nov 16. PMID 17108953
    3. Behavior Responses to Chemical and Optogenetic Stimuli in Drosophila Larvae. Clark DA, et al. Front Behav Neurosci, 2018. PMID 30622461, Free PMC Article
    4. Evolution of herbivory in Drosophilidae linked to loss of behaviors, antennal responses, odorant receptors, and ancestral diet. Goldman-Huertas B, et al. Proc Natl Acad Sci U S A, 2015 Mar 10. PMID 25624509, Free PMC Article
    5. Genetic variation in odorant receptors contributes to variation in olfactory behavior in a natural population of Drosophila melanogaster. Richgels PK, et al. Chem Senses, 2012 Mar. PMID 22038943, Free PMC Article

    See all (80) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables odorant binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables odorant binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus involved in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in detection of chemical stimulus involved in sensory perception of smell IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in dendrite membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    odorant receptor 67b
    Names
    CG14176-PB
    Or67b-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      9627316..9629193 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079283.5 → NP_524007.2  odorant receptor 67b [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524007.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q4V3I3, Q9VT20
      UniProtKB/TrEMBL
      E2E624, E2E628, E2E640, E2E652, E2E679, E2E6A5, E2E6C9, E5AJS2
      Related
      FBpp0076149
      Conserved Domains (1) summary
      pfam02949
      Location:197 → 408
      7tm_6; 7tm Odorant receptor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VT20.2 Q9VT20

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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