Gpa2 Glycoprotein hormone alpha 2 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Gpa2provided by FlyBase
Official Full Name: Glycoprotein hormone alpha 2provided by FlyBase
Primary source: FLYBASE:FBgn0261386
Locus tag: Dmel_CG17878
See related: AllianceGenome:FB:FBgn0261386
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG17878; Dmel\CG17878; gpa2; GPA2
Summary: Enables protein heterodimerization activity. Contributes to G protein-coupled receptor binding activity and hormone activity. Involved in G protein-coupled receptor signaling pathway. Predicted to be active in extracellular space. Is expressed in larval GPA2/GPB5 neuron of the ventral nerve cord. Orthologous to human GPHA2 (glycoprotein hormone subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	Unplaced Scaffold	NW_007931083.1 (3093..3557, complement)

NW_007931083.1 Genomic Context describing neighboring genes

Genomic Sequence:: NW_007931083.1 Unplaced Scaffold Reference Release 6 plus ISO1 MT Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

Function	Evidence Code	Pubs
contributes_to G protein-coupled receptor binding	IPI Inferred from Physical Interaction more info	PubMed
contributes_to hormone activity	IDA Inferred from Direct Assay more info	PubMed
enables hormone receptor binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein heterodimerization activity	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IDA Inferred from Direct Assay more info	PubMed
involved_in cell surface receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular space	IC Inferred by Curator more info	PubMed

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