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    CG18508 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 59253, updated on 10-May-2024

    Summary

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    Official Symbol
    CG18508provided by FlyBase
    Primary source
    FLYBASE:FBgn0028746
    Locus tag
    Dmel_CG18508
    See related
    AllianceGenome:FB:FBgn0028746
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG4015; Dmel\CG18508; EG:140G11.3
    Summary
    Is expressed in adult head; embryonic/larval midgut; and organism. Orthologous to human C18orf32 (chromosome 18 open reading frame 32). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG18508 in Genome Data Viewer
    Location:
    3C9-3C9; 1-2 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (3172268..3173140, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (3066301..3067173, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene kin of irre Neighboring gene uncharacterized protein Neighboring gene Notch Neighboring gene uncharacterized protein Neighboring gene Follicle cell protein 3C

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Multiple signatures of positive selection downstream of notch on the X chromosome in Drosophila melanogaster. DuMont VB, et al. Genetics, 2005 Oct. PMID 16020794, Free PMC Article
    2. Patterns of sequence variability and divergence at the diminutive gene region of Drosophila melanogaster: complex patterns suggest an ancestral selective sweep. Jensen JD, et al. Genetics, 2007 Oct. PMID 17720938, Free PMC Article
    3. Population Genomics on the Fly: Recent Advances in Drosophila. Haudry A, et al. Methods Mol Biol, 2020. PMID 31975175
    4. Genome-wide analysis reveals an unexpected function for the Drosophila splicing factor U2AF50 in the nuclear export of intronless mRNAs. Blanchette M, et al. Mol Cell, 2004 Jun 18. PMID 15200955
    5. Impaired retrograde transport by the Dynein/Dynactin complex contributes to Tau-induced toxicity. Butzlaff M, et al. Hum Mol Genet, 2015 Jul 1. PMID 25794683

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG18508-PA
    CG18508-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      3172268..3173140 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001297907.1 → NP_001284836.1  uncharacterized protein Dmel_CG18508, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284836.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O97172, Q32UZ2
      UniProtKB/TrEMBL
      F3YDJ5
      Conserved Domains (1) summary
      pfam14975
      Location:2 → 96
      DUF4512; Domain of unknown function (DUF4512)

    2. NM_144464.3 → NP_652721.1  uncharacterized protein Dmel_CG18508, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652721.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O97172, Q32UZ2
      UniProtKB/TrEMBL
      F3YDJ5
      Related
      FBpp0070518
      Conserved Domains (1) summary
      pfam14975
      Location:2 → 96
      DUF4512; Domain of unknown function (DUF4512)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F3YDJ5 F3YDJ5
    O97172.1 O97172
    Q8SYT4 Q8SYT4

    Gene LinkOut

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