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    MADCAM1 mucosal vascular addressin cell adhesion molecule 1 [ Ovis aries (sheep) ]

    Gene ID: 654333, updated on 5-Mar-2024

    Summary

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    Gene symbol
    MADCAM1
    Gene description
    mucosal vascular addressin cell adhesion molecule 1
    See related
    EnsemblRapid:ENSOARG00020010809
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Also known as
    MADCAM-1
    Orthologs
    human mouse all
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    Genomic context

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    See MADCAM1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 5 NC_056058.1 (40832439..40837154)

    Chromosome 5 - NC_056058.1Genomic Context describing neighboring genes Neighboring gene SHC adaptor protein 2 Neighboring gene CIMAP1 family member D Neighboring gene uncharacterized LOC132659882 Neighboring gene tubulin polyglutamylase complex subunit 1 Neighboring gene cell division cycle 34, ubiqiutin conjugating enzyme

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056058.1 Chromosome 5 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning and characterization of pig, cow and sheep MAdCAM-1 cDNA and the demonstration of cross-reactive epitopes amongst mammalian homologues. Tachedjian M, et al. Tissue Antigens, 2006 May. PMID 16671951

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables integrin binding involved in cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in heterotypic cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in leukocyte tethering or rolling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of lymphocyte migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mucosal addressin cell adhesion molecule 1
    Names
    mucosal addressin cellular adhesion molecule-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001038020.1 → NP_001033109.1  mucosal addressin cell adhesion molecule 1 precursor

      See identical proteins and their annotated locations for NP_001033109.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ288287
      UniProtKB/TrEMBL
      A0A6P3CWN1, A0A836D1R8, Q2V6R7
      Related
      ENSOARP00020013671.2, ENSOART00020016530.2
      Conserved Domains (2) summary
      pfam09085
      Location:112 → 217
      Adhes-Ig_like; Adhesion molecule, immunoglobulin-like
      cl11960
      Location:24 → 99
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056058.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      40832439..40837154
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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