Kirrel3 kirre like nephrin family adhesion molecule 3 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Kirrel3provided by MGI
Official Full Name: kirre like nephrin family adhesion molecule 3provided by MGI
Primary source: MGI:MGI:1914953
See related: Ensembl:ENSMUSG00000032036 AllianceGenome:MGI:1914953
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: SST4; NEPH2; mKIAA1867; 1500010O20Rik; 2900036G11Rik
Summary: Predicted to enable cell adhesion molecule binding activity. Involved in hemopoiesis; homophilic cell adhesion via plasma membrane adhesion molecules; and nervous system development. Acts upstream of or within glomerulus morphogenesis; inter-male aggressive behavior; and nervous system development. Located in several cellular components, including axon; dendritic shaft; and extracellular region. Is integral component of membrane. Is expressed in central nervous system; dorsal root ganglion; glomerular tuft; and sensory organ. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 4. Orthologous to human KIRREL3 (kirre like nephrin family adhesion molecule 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in cerebellum adult (RPKM 9.9), frontal lobe adult (RPKM 5.7) and 7 other tissues See more
Orthologs: human all
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Genomic context

Location:: 9 A4; 9 18.97 cM

Exon count:: 26

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	9	NC_000075.7 (34396850..34952103)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	9	NC_000075.6 (34485853..35040807)

Chromosome 9 - NC_000075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors.
Title: Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors.
Comprehensive expression pattern of kin of irregular chiasm-like 3 in the adult mouse brain.
Title: Comprehensive expression pattern of kin of irregular chiasm-like 3 in the adult mouse brain.
Kirrel3-Mediated Synapse Formation Is Attenuated by Disease-Associated Missense Variants.
Title: Kirrel3-Mediated Synapse Formation Is Attenuated by Disease-Associated Missense Variants.
Kirrel2 is required for axonal coalescence in subsets of Olfactory sensory neurons that project axons to the DII (dorsal) region; Kirrel2/3-independent mechanisms also control olfactory sensory neurons axonal coalescence in certain regions of the Olfactory bulb.
Title: Kirrel2 is differentially required in populations of olfactory sensory neurons for the targeting of axons in the olfactory bulb.
The results of this study demonstrate that Kirrel2 and Kirrel3 are essential for the formation of glomeruli and suggest they contribute to synaptogenesis in the accessory olfactory bulb.
Title: Loss of Kirrel family members alters glomerular structure and synapse numbers in the accessory olfactory bulb.
Findings provide evidence that Kirrel3(-/-) mice exhibit autistic-like behaviors, including social and communicative deficits, repetitive behaviors, and sensory abnormalities, as well as hyperactivity.
Title: Abnormal behaviours relevant to neurodevelopmental disorders in Kirrel3-knockout mice.
This study demonstrated that selective loss of mossy fiber filopodial synapses with GABA neurons likely underlies the hippocampal activity imbalance observed in Kirrel3 knockout mice and may impact neural function in patients with Kirrel3-dependent neurodevelopmental disorders.
Title: Examining Hippocampal Mossy Fiber Synapses by 3D Electron Microscopy in Wildtype and Kirrel3 Knockout Mice.
mouse Kirrel3 is a myobast adhesion molecule which promotes the morphological change of rounded MPC to a spindle shaped myocyte that migrates in a directed fashion and participates in the tight interactions between myocytes prior to their fusion
Title: Adhesion molecule Kirrel3/Neph2 is required for the elongated shape of myocytes during skeletal muscle differentiation.
Kirrel3 is required for formation of hippocampal mossy fiber filopodia; the structures that give rise to dentate granule-GABA synapses and that regulate feed-forward inhibition of CA3 neurons.
Title: The intellectual disability gene Kirrel3 regulates target-specific mossy fiber synapse development in the hippocampus.
Kirrel3 has a role in coalescence of vomeronasal sensory neuron axons into glomeruli and in male-male aggression in a resident-intruder assay
Title: Kirrel3 is required for the coalescence of vomeronasal sensory neuron axons into glomeruli and for male-male aggression.

Submit: New GeneRIF Correction See all GeneRIFs (17)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2) 1 citation
Targeted (4) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

fb98c02.x1 (e-PCR)
- UniSTS:203609

D9Mit66 (e-PCR), detects polymorphism
- UniSTS:131952

MHAa21d4.seq (e-PCR)
- UniSTS:125087

27.MMHAP9FRA12.seq (e-PCR)
- UniSTS:123808

05.MMHAP38FLB2.seq (e-PCR)
- UniSTS:122812

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables PDZ domain binding	NAS Non-traceable Author Statement more info	PubMed
enables cell adhesion molecule binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell adhesion	IEA Inferred from Electronic Annotation more info
involved_in cell-cell adhesion	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within glomerulus morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in hemopoiesis	IDA Inferred from Direct Assay more info	PubMed
involved_in hippocampus development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in homophilic cell adhesion via plasma membrane adhesion molecules	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within inter-male aggressive behavior	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within neuron migration	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within neuron projection morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within principal sensory nucleus of trigeminal nerve development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in synapse assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in synapse assembly	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in axon	IDA Inferred from Direct Assay more info	PubMed
located_in cell projection	IEA Inferred from Electronic Annotation more info
is_active_in cell-cell junction	IBA Inferred from Biological aspect of Ancestor more info
located_in dendrite	IDA Inferred from Direct Assay more info	PubMed
located_in dendritic shaft	IDA Inferred from Direct Assay more info	PubMed
located_in extracellular region	IDA Inferred from Direct Assay more info	PubMed
located_in membrane	IDA Inferred from Direct Assay more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in synaptic vesicle	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: kin of IRRE-like protein 3

Names: X kin of IRRE like 3; kin of IRRE like 3; kin of irregular chiasm-like protein 3; membrane protein mKirre; nephrin-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001190911.1 → NP_001177840.1 kin of IRRE-like protein 3 isoform A precursor

See identical proteins and their annotated locations for NP_001177840.1

Status: VALIDATED

Description

Transcript Variant: This variant (A) encodes the longest isoform (A).

Source sequence(s)

AC155250, AC156639, AK045373

UniProtKB/Swiss-Prot

Q6P555, Q810H3, Q8BGQ5, Q8BR86, Q8BRS8

Conserved Domains (4) summary

cd00096
Location:343 → 347

Ig; Ig strand A' [structural motif]

cd05759
Location:149 → 246

IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05898
Location:418 → 515

IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:335 → 416

Ig; Immunoglobulin domain
NM_001190912.1 → NP_001177841.1 kin of IRRE-like protein 3 isoform C precursor

See identical proteins and their annotated locations for NP_001177841.1

Status: VALIDATED

Description

Transcript Variant: This variant (C) lacks an in-frame exon in the 5' coding region and uses an alternate in-frame splice site in the 3' coding region, compared to variant A. The resulting protein (isoform C) is shorter than isoform A.

Source sequence(s)

AC155250, AC156639, BC063072

Consensus CDS

CCDS80973.1

UniProtKB/TrEMBL

Q3TAG1

Related

ENSMUSP00000140219.2, ENSMUST00000187182.7

Conserved Domains (4) summary

cd05759
Location:139 → 220

Ig2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2)

cd05898
Location:392 → 489

Ig5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein (also known as Neph2)

smart00409
Location:28 → 117

IG; Immunoglobulin

cl11960
Location:309 → 390

Ig; Immunoglobulin domain
NM_001190913.1 → NP_001177842.1 kin of IRRE-like protein 3 isoform D precursor

See identical proteins and their annotated locations for NP_001177842.1

Status: VALIDATED

Description

Transcript Variant: This variant (D) lacks an in-frame exon and uses an alternate splice site, which results in a frameshift, in the 3' coding region, compared to variant A. The resulting protein (isoform D) has a shorter and distinct C-terminus, compared to isoform A.

Source sequence(s)

AC155250, AC156639, AK034142

UniProtKB/TrEMBL

A0A087WPC0

Related

ENSMUSP00000139714.2, ENSMUST00000190549.7

Conserved Domains (7) summary

cd05759
Location:165 → 246

Ig2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2)

cd05898
Location:418 → 515

Ig5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein (also known as Neph2)

smart00408
Location:349 → 400

IGc2; Immunoglobulin C-2 Type

smart00410
Location:426 → 515

IG_like; Immunoglobulin like

pfam07679
Location:335 → 416

I-set; Immunoglobulin I-set domain

pfam13927
Location:254 → 318

Ig_3; Immunoglobulin domain

cl11960
Location:52 → 143

Ig; Immunoglobulin domain
NM_001190914.1 → NP_001177843.1 kin of IRRE-like protein 3 isoform E

See identical proteins and their annotated locations for NP_001177843.1

Status: VALIDATED

Description

Transcript Variant: This variant (E) contains an alternate exon in the 5' coding region, uses a downstream start codon and lacks an in-frame exon in the 3' coding region, compared to variant A. The resulting protein (isoform E) has a shorter N-terminus than isoform A.

Source sequence(s)

AC155250, AC156639, AK079332

Consensus CDS

CCDS57667.1

UniProtKB/TrEMBL

G5E8B6, Q3TAG1

Related

ENSMUSP00000048863.7, ENSMUST00000045091.13

Conserved Domains (5) summary

smart00410
Location:21 → 110

IG_like; Immunoglobulin like

cd00096
Location:310 → 314

Ig; Ig strand A' [structural motif]

cd05759
Location:116 → 213

IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05898
Location:385 → 482

IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:302 → 383

Ig; Immunoglobulin domain
NM_026324.3 → NP_080600.1 kin of IRRE-like protein 3 isoform B precursor

See identical proteins and their annotated locations for NP_080600.1

Status: VALIDATED

Description

Transcript Variant: This variant (B) lacks an in-frame exon in the 3' coding region, compared to variant 1. The resulting protein (isoform B) is shorter than isoform A.

Source sequence(s)

AC155250, AC156639

Consensus CDS

CCDS40574.1

UniProtKB/TrEMBL

Q3TAG1

Conserved Domains (4) summary

cd05759
Location:165 → 246

Ig2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2)

cd05898
Location:418 → 515

Ig5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein (also known as Neph2)

smart00410
Location:54 → 143

IG_like; Immunoglobulin like

cl11960
Location:335 → 416

Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000075.7 Reference GRCm39 C57BL/6J

Range

34396850..34952103

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036155204.1 → XP_036011097.1 kin of IRRE-like protein 3 isoform X1

Conserved Domains (5) summary

smart00410
Location:54 → 143

IG_like; Immunoglobulin like

cd00096
Location:343 → 347

Ig; Ig strand A' [structural motif]

cd05759
Location:149 → 246

IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05898
Location:418 → 515

IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:335 → 416

Ig; Immunoglobulin domain
XM_006510557.5 → XP_006510620.1 kin of IRRE-like protein 3 isoform X1

See identical proteins and their annotated locations for XP_006510620.1

Conserved Domains (5) summary

smart00410
Location:54 → 143

IG_like; Immunoglobulin like

cd00096
Location:343 → 347

Ig; Ig strand A' [structural motif]

cd05759
Location:149 → 246

IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05898
Location:418 → 515

IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:335 → 416

Ig; Immunoglobulin domain
XM_006510560.5 → XP_006510623.1 kin of IRRE-like protein 3 isoform X3

See identical proteins and their annotated locations for XP_006510623.1

UniProtKB/Swiss-Prot

Q6P555, Q810H3, Q8BGQ5, Q8BR86, Q8BRS8

Conserved Domains (4) summary

cd00096
Location:343 → 347

Ig; Ig strand A' [structural motif]

cd05759
Location:149 → 246

IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05898
Location:418 → 515

IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:335 → 416

Ig; Immunoglobulin domain
XM_006510559.5 → XP_006510622.1 kin of IRRE-like protein 3 isoform X2

Conserved Domains (4) summary

cd05759
Location:165 → 246

Ig2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2)

cd05898
Location:418 → 515

Ig5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein (also known as Neph2)

smart00409
Location:54 → 143

IG; Immunoglobulin

cl11960
Location:335 → 416

Ig; Immunoglobulin domain
XM_006510563.5 → XP_006510626.1 kin of IRRE-like protein 3 isoform X6

See identical proteins and their annotated locations for XP_006510626.1

UniProtKB/TrEMBL

Q3TAG1

Related

ENSMUSP00000110801.3, ENSMUST00000115148.9

Conserved Domains (4) summary

cd05759
Location:165 → 246

Ig2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2)

cd05898
Location:418 → 515

Ig5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein (also known as Neph2)

smart00410
Location:54 → 143

IG_like; Immunoglobulin like

cl11960
Location:335 → 416

Ig; Immunoglobulin domain
XM_006510558.5 → XP_006510621.1 kin of IRRE-like protein 3 isoform X1

See identical proteins and their annotated locations for XP_006510621.1

Conserved Domains (5) summary

smart00410
Location:54 → 143

IG_like; Immunoglobulin like

cd00096
Location:343 → 347

Ig; Ig strand A' [structural motif]

cd05759
Location:149 → 246

IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05898
Location:418 → 515

IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:335 → 416

Ig; Immunoglobulin domain
XM_036155205.1 → XP_036011098.1 kin of IRRE-like protein 3 isoform X3

UniProtKB/Swiss-Prot

Q6P555, Q810H3, Q8BGQ5, Q8BR86, Q8BRS8

Conserved Domains (4) summary

cd00096
Location:343 → 347

Ig; Ig strand A' [structural motif]

cd05759
Location:149 → 246

IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05898
Location:418 → 515

IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:335 → 416

Ig; Immunoglobulin domain
XM_006510561.5 → XP_006510624.1 kin of IRRE-like protein 3 isoform X4

See identical proteins and their annotated locations for XP_006510624.1

UniProtKB/TrEMBL

Q3TAG1

Conserved Domains (4) summary

cd05759
Location:139 → 220

Ig2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2)

cd05898
Location:392 → 489

Ig5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein (also known as Neph2)

smart00409
Location:28 → 117

IG; Immunoglobulin

cl11960
Location:309 → 390

Ig; Immunoglobulin domain
XM_036155207.1 → XP_036011100.1 kin of IRRE-like protein 3 isoform X5

UniProtKB/TrEMBL

Q3TAG1

Conserved Domains (5) summary

smart00410
Location:21 → 110

IG_like; Immunoglobulin like

cd00096
Location:310 → 314

Ig; Ig strand A' [structural motif]

cd05759
Location:116 → 213

IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05898
Location:385 → 482

IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:302 → 383

Ig; Immunoglobulin domain
XM_036155211.1 → XP_036011104.1 kin of IRRE-like protein 3 isoform X7

UniProtKB/TrEMBL

Q3TAG1

Conserved Domains (5) summary

smart00410
Location:28 → 117

IG_like; Immunoglobulin like

cd00096
Location:317 → 321

Ig; Ig strand A' [structural motif]

cd05759
Location:123 → 220

IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05898
Location:392 → 489

IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:309 → 390

Ig; Immunoglobulin domain
XM_036155206.1 → XP_036011099.1 kin of IRRE-like protein 3 isoform X5

UniProtKB/TrEMBL

Q3TAG1

Conserved Domains (5) summary

smart00410
Location:21 → 110

IG_like; Immunoglobulin like

cd00096
Location:310 → 314

Ig; Ig strand A' [structural motif]

cd05759
Location:116 → 213

IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05898
Location:385 → 482

IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:302 → 383

Ig; Immunoglobulin domain
XM_036155208.1 → XP_036011101.1 kin of IRRE-like protein 3 isoform X5

UniProtKB/TrEMBL

Q3TAG1

Conserved Domains (5) summary

smart00410
Location:21 → 110

IG_like; Immunoglobulin like

cd00096
Location:310 → 314

Ig; Ig strand A' [structural motif]

cd05759
Location:116 → 213

IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05898
Location:385 → 482

IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:302 → 383

Ig; Immunoglobulin domain
XM_036155213.1 → XP_036011106.1 kin of IRRE-like protein 3 isoform X9

UniProtKB/TrEMBL

G5E8B6, Q3TAG1

Conserved Domains (5) summary

smart00410
Location:21 → 110

IG_like; Immunoglobulin like

cd00096
Location:310 → 314

Ig; Ig strand A' [structural motif]

cd05759
Location:116 → 213

IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05898
Location:385 → 482

IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:302 → 383

Ig; Immunoglobulin domain
XM_036155210.1 → XP_036011103.1 kin of IRRE-like protein 3 isoform X5

UniProtKB/TrEMBL

Q3TAG1

Conserved Domains (5) summary

smart00410
Location:21 → 110

IG_like; Immunoglobulin like

cd00096
Location:310 → 314

Ig; Ig strand A' [structural motif]

cd05759
Location:116 → 213

IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05898
Location:385 → 482

IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:302 → 383

Ig; Immunoglobulin domain
XM_030244529.2 → XP_030100389.1 kin of IRRE-like protein 3 isoform X8

UniProtKB/TrEMBL

A0A087WNM9, Q3TAG1

Related

ENSMUSP00000139418.2, ENSMUST00000188933.7

Conserved Domains (5) summary

smart00410
Location:21 → 110

IG_like; Immunoglobulin like

cd00096
Location:310 → 314

Ig; Ig strand A' [structural motif]

cd05759
Location:116 → 213

IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05898
Location:385 → 482

IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:302 → 383

Ig; Immunoglobulin domain
XM_036155214.1 → XP_036011107.1 kin of IRRE-like protein 3 isoform X9

UniProtKB/TrEMBL

G5E8B6, Q3TAG1

Conserved Domains (5) summary

smart00410
Location:21 → 110

IG_like; Immunoglobulin like

cd00096
Location:310 → 314

Ig; Ig strand A' [structural motif]

cd05759
Location:116 → 213

IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05898
Location:385 → 482

IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:302 → 383

Ig; Immunoglobulin domain
XM_036155209.1 → XP_036011102.1 kin of IRRE-like protein 3 isoform X5

UniProtKB/TrEMBL

Q3TAG1

Conserved Domains (5) summary

smart00410
Location:21 → 110

IG_like; Immunoglobulin like

cd00096
Location:310 → 314

Ig; Ig strand A' [structural motif]

cd05759
Location:116 → 213

IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05898
Location:385 → 482

IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:302 → 383

Ig; Immunoglobulin domain
XM_017313538.3 → XP_017169027.1 kin of IRRE-like protein 3 isoform X5

UniProtKB/TrEMBL

Q3TAG1

Conserved Domains (5) summary

smart00410
Location:21 → 110

IG_like; Immunoglobulin like

cd00096
Location:310 → 314

Ig; Ig strand A' [structural motif]

cd05759
Location:116 → 213

IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05898
Location:385 → 482

IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:302 → 383

Ig; Immunoglobulin domain
XM_017313539.3 → XP_017169028.1 kin of IRRE-like protein 3 isoform X9

UniProtKB/TrEMBL

G5E8B6, Q3TAG1

Conserved Domains (5) summary

smart00410
Location:21 → 110

IG_like; Immunoglobulin like

cd00096
Location:310 → 314

Ig; Ig strand A' [structural motif]

cd05759
Location:116 → 213

IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05898
Location:385 → 482

IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:302 → 383

Ig; Immunoglobulin domain
XM_036155212.1 → XP_036011105.1 kin of IRRE-like protein 3 isoform X8

UniProtKB/TrEMBL

A0A087WNM9, Q3TAG1

Conserved Domains (5) summary

smart00410
Location:21 → 110

IG_like; Immunoglobulin like

cd00096
Location:310 → 314

Ig; Ig strand A' [structural motif]

cd05759
Location:116 → 213

IgI_2_KIRREL3-like; Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3, and similar domains; member of the I-set of Ig superfamily (IgSF) domains

cd05898
Location:385 → 482

IgI_5_KIRREL3; Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein; member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:302 → 383

Ig; Immunoglobulin domain