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    Fib-l silk fibroin light chain [ Bombyx mori (domestic silkworm) ]

    Gene ID: 693047, updated on 9-Feb-2024

    Summary

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    Gene symbol
    Fib-l
    Gene description
    silk fibroin light chain
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bombyx mori
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea; Bombycidae; Bombycinae; Bombyx
    Also known as
    FIBL; Fib-1; fibroin
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    Genomic context

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    See Fib-l in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_01 current ASM3026992v2 (GCF_030269925.1) 14 NC_085120.1 (9684953..9698235, complement)
    103 previous assembly Bmori_2016v1.0 (GCF_014905235.1) 14 NC_051371.1 (9685264..9698548, complement)

    Chromosome 14 - NC_085120.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105841523 Neighboring gene uncharacterized LOC101743535 Neighboring gene uncharacterized LOC105841524 Neighboring gene uncharacterized LOC134200124

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Bom-miR-2805 upregulates the expression of Bombyx mori fibroin light chain gene in vivo. Chen Y, et al. J Cell Biochem, 2019 Sep. PMID 31106458
    2. Production of a chimeric fibroin light-chain polypeptide in a fibroin secretion-deficient naked pupa mutant of the silkworm Bombyx mori. Mori K, et al. J Mol Biol, 1995 Aug 11. PMID 7643398
    3. Primary structure of the silk fibroin light chain determined by cDNA sequencing and peptide analysis. Yamaguchi K, et al. J Mol Biol, 1989 Nov 5. PMID 2585514
    4. Structure of the Bombyx mori fibroin light-chain-encoding gene: upstream sequence elements common to the light and heavy chain. Kikuchi Y, et al. Gene, 1992 Jan 15. PMID 1347033
    5. Time-resolved structural investigation of regenerated silk fibroin nanofibers treated with solvent vapor. Jeong L, et al. Int J Biol Macromol, 2006 Mar 30. PMID 16545448

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Bom-miR-2805 upregulates the expression of Bombyx mori fibroin light chain gene in vivo.
      Title: Bom-miR-2805 upregulates the expression of Bombyx mori fibroin light chain gene in vivo.
    2. At least 4 microRNAs target fibroin L chain transcripts, suggesting that miRNAs might play an important role in the regulation of silk protein production.
      Title: Identification of conserved microRNAs in Bombyx mori (silkworm) and regulation of fibroin L chain production by microRNAs in heterologous system.
    3. Structural changes of solvent-vapor-treated SF nanofibers were studied using time-resolved IR spectroscopy. Conformational transitions from random coils to beta-sheets depended on the solvent vapor used. Treatment temperatures affected transition rates.
      Title: Time-resolved structural investigation of regenerated silk fibroin nanofibers treated with solvent vapor.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    fibroin light chain
    Names
    L-fibroin
    fibroin L-chain

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044023.1 → NP_001037488.1  fibroin light chain precursor

      See identical proteins and their annotated locations for NP_001037488.1

      Status: PROVISIONAL

      Source sequence(s)
      M76430
      UniProtKB/Swiss-Prot
      P21828, Q17224
      UniProtKB/TrEMBL
      A0A8R1XET8
      Conserved Domains (1) summary
      pfam05849
      Location:18 → 256
      L-fibroin; Fibroin light chain (L-fibroin)

    RefSeqs of Annotated Genomes: GCF_030269925.1-RS_2024_01

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM3026992v2 Primary Assembly

    Genomic

    1. NC_085120.1 Reference ASM3026992v2 Primary Assembly

      Range
      9684953..9698235 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P21828.1 GenPept UniProtKB/Swiss-Prot:P21828

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials