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    HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 702553, updated on 5-Mar-2024

    Summary

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    Official Symbol
    HMGCS1provided by VGNC
    Official Full Name
    3-hydroxy-3-methylglutaryl-CoA synthase 1provided by VGNC
    Primary source
    VGNC:VGNC:73485
    Locus tag
    EGK_21191
    See related
    Ensembl:ENSMMUG00000001226
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See HMGCS1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (43297245..43321487, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (44074478..44099004, complement)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene spermine synthase pseudogene Neighboring gene NIM1 serine/threonine protein kinase Neighboring gene tubulin alpha-1C chain pseudogene Neighboring gene 60S acidic ribosomal protein P1 pseudogene Neighboring gene uncharacterized LOC106998744 Neighboring gene C-C motif chemokine ligand 28

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables hydroxymethylglutaryl-CoA synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in acetyl-CoA metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hydroxymethylglutaryl-CoA synthase, cytoplasmic
    Names
    3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
    3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)
    NP_001247798.1
    XP_014995459.1
    XP_014995460.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001260869.1 → NP_001247798.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

      See identical proteins and their annotated locations for NP_001247798.1

      Status: PROVISIONAL

      Source sequence(s)
      JV045478
      UniProtKB/TrEMBL
      F7HQ90, G8F1C3, H9ETD6
      Related
      ENSMMUP00000034768.1, ENSMMUT00000041755.3
      Conserved Domains (1) summary
      TIGR01833
      Location:13 → 469
      HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      43297245..43321487 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015139973.2 → XP_014995459.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X1

      UniProtKB/TrEMBL
      F7HQ90, G8F1C3, H9ETD6
      Related
      ENSMMUP00000062864.1, ENSMMUT00000097092.1
      Conserved Domains (1) summary
      TIGR01833
      Location:13 → 469
      HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

    2. XM_015139974.2 → XP_014995460.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X1

      UniProtKB/TrEMBL
      F7HQ90, G8F1C3, H9ETD6
      Conserved Domains (1) summary
      TIGR01833
      Location:13 → 469
      HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
    Nucleotide Protein
    Heading Accession and Version

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