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    ighv4-8 immunoglobulin heavy variable 4-8 [ Danio rerio (zebrafish) ]

    Gene ID: 777741, updated on 23-Nov-2023

    Summary

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    Official Symbol
    ighv4-8provided by ZNC
    Official Full Name
    immunoglobulin heavy variable 4-8provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040514-13
    See related
    AllianceGenome:ZFIN:ZDB-GENE-040514-13
    Gene type
    other
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Predicted to be involved in several processes, including activation of immune response; defense response to other organism; and phagocytosis. Predicted to be part of immunoglobulin complex, circulating. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Annotation information
    not in current annotation release
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    Genomic context

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    Location:
    chromosome: 3

    Bibliography

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    Related articles in PubMed

    1. The role of adaptive immunity as an ecological filter on the gut microbiota in zebrafish. Stagaman K, et al. ISME J, 2017 Jul. PMID 28304369, Free PMC Article
    2. Determinism and stochasticity during maturation of the zebrafish antibody repertoire. Jiang N, et al. Proc Natl Acad Sci U S A, 2011 Mar 29. PMID 21393572, Free PMC Article
    3. The immunoglobulin heavy-chain locus in zebrafish: identification and expression of a previously unknown isotype, immunoglobulin Z. Danilova N, et al. Nat Immunol, 2005 Mar. PMID 15685175
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables antigen binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in immunoglobulin mediated immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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