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    MYD88 MYD88 innate immune signal transduction adaptor [ Cercocebus atys (sooty mangabey) ]

    Gene ID: 105573904, updated on 13-Mar-2024

    Summary

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    Gene symbol
    MYD88
    Gene description
    MYD88 innate immune signal transduction adaptor
    See related
    Ensembl:ENSCATG00000044210
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Cercocebus atys
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012003613.1 (6312022..6316569, complement)

    NW_012003613.1Genomic Context describing neighboring genes Neighboring gene cell division control protein 42 homolog Neighboring gene solute carrier family 22 member 13 Neighboring gene oxidative stress responsive kinase 1 Neighboring gene acetyl-CoA acyltransferase 1 Neighboring gene DLEC1 cilia and flagella associated protein Neighboring gene serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform pseudogene

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_012003613.1 Unplaced Scaffold Reference Caty_1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections. Mandl JN, et al. Nat Med, 2008 Oct. PMID 18806803

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables TIR domain binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables Toll-like receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in MyD88-dependent toll-like receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in Toll signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to Gram-positive bacterium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myeloid differentiation primary response protein MyD88
    Names
    myeloid differentiation primary response 88
    myeloid differentiation primary response protein 88

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001305949.1 → NP_001292878.1  myeloid differentiation primary response protein MyD88

      See identical proteins and their annotated locations for NP_001292878.1

      Status: PROVISIONAL

      Source sequence(s)
      EU204915
      UniProtKB/Swiss-Prot
      B6CJX2
      Conserved Domains (2) summary
      smart00255
      Location:160 → 296
      TIR; Toll - interleukin 1 - resistance
      cd08312
      Location:29 → 106
      Death_MyD88; Death domain of Myeloid Differentation primary response protein MyD88

    RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Caty_1.0

    Genomic

    1. NW_012003613.1 Reference Caty_1.0

      Range
      6312022..6316569 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012034270.1 → XP_011889660.1  myeloid differentiation primary response protein MyD88 isoform X3

      UniProtKB/TrEMBL
      A0A2K5P0S0
      Related
      ENSCATP00000043338.1, ENSCATT00000067777.1
      Conserved Domains (1) summary
      cd08312
      Location:42 → 119
      Death_MyD88; Death domain of Myeloid Differentation primary response protein MyD88

    2. XM_012034269.1 → XP_011889659.1  myeloid differentiation primary response protein MyD88 isoform X2

      UniProtKB/TrEMBL
      A0A2K5P0X3
      Related
      ENSCATP00000043337.1, ENSCATT00000067776.1
      Conserved Domains (1) summary
      cd08312
      Location:42 → 119
      Death_MyD88; Death domain of Myeloid Differentation primary response protein MyD88

    3. XM_012034268.1 → XP_011889658.1  myeloid differentiation primary response protein MyD88 isoform X1

      Related
      ENSCATP00000043331.1, ENSCATT00000067770.1
      Conserved Domains (2) summary
      smart00255
      Location:173 → 309
      TIR; Toll - interleukin 1 - resistance
      cd08312
      Location:42 → 119
      Death_MyD88; Death domain of Myeloid Differentation primary response protein MyD88
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B6CJX2.1 GenPept UniProtKB/Swiss-Prot:B6CJX2

    Gene LinkOut

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