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nef Nef [ Human immunodeficiency virus 1 ]

Gene ID: 156110, updated on 4-Apr-2024

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Summary

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Gene symbol: nef
Gene description: Nef
Locus tag: HIV1gp9
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Human immunodeficiency virus 1
Lineage: Viruses; Retro-transcribing viruses; Retroviridae; Orthoretrovirinae; Lentivirus; Primate lentivirus group
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Genomic context

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Sequence:: NC_001802.1 (8343..8963)

NC_001802.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_001802.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Cellular HSF1 expression is induced during HIV-1 infection by activation of its promoter mediated through the cooperative interaction of HSF1 and viral Nef protein.
Title: Cellular HSF1 expression is induced during HIV-1 infection by activation of its promoter mediated through the cooperative interaction of HSF1 and viral Nef protein.
NEF-Induced HIV-Associated Nephropathy Through HCK/LYN Tyrosine Kinases.
Title: NEF-Induced HIV-Associated Nephropathy Through HCK/LYN Tyrosine Kinases.
A Conserved Acidic Residue in the C-Terminal Flexible Loop of HIV-1 Nef Contributes to the Activity of SERINC5 and CD4 Downregulation.
Title: A Conserved Acidic Residue in the C-Terminal Flexible Loop of HIV-1 Nef Contributes to the Activity of SERINC5 and CD4 Downregulation.
Novel role of HIV-1 Nef in regulating the ubiquitination of cellular proteins.
Title: Novel role of HIV-1 Nef in regulating the ubiquitination of cellular proteins.
AP-2 Adaptor Complex-Dependent Enhancement of HIV-1 Replication by Nef in the Absence of the Nef/AP-2 Targets SERINC5 and CD4.
Title: AP-2 Adaptor Complex-Dependent Enhancement of HIV-1 Replication by Nef in the Absence of the Nef/AP-2 Targets SERINC5 and CD4.
Nef enhances HIV-1 replication and infectivity independently of SERINC5 in CEM T cells.
Title: Nef enhances HIV-1 replication and infectivity independently of SERINC5 in CEM T cells.
Nef inhibits HIV transcription and gene expression in astrocytes and HIV transmission from astrocytes to CD4[+] T cells.
Title: Nef inhibits HIV transcription and gene expression in astrocytes and HIV transmission from astrocytes to CD4(+) T cells.
Abundance of Nef and p-Tau217 in Brains of Individuals Diagnosed with HIV-Associated Neurocognitive Disorders Correlate with Disease Severance.
Title: Abundance of Nef and p-Tau217 in Brains of Individuals Diagnosed with HIV-Associated Neurocognitive Disorders Correlate with Disease Severance.
HIV-1 Nef Protein Affects Cytokine and Extracellular Vesicles Production in the GEN2.2 Plasmacytoid Dendritic Cell Line.
Title: HIV-1 Nef Protein Affects Cytokine and Extracellular Vesicles Production in the GEN2.2 Plasmacytoid Dendritic Cell Line.
Molecular and Genetic Characterization of Natural Variants of HIV-1 Nef Gene from North India and its Functional Implication in Down-Regulation of MHC-I and CD-4.
Title: Molecular and Genetic Characterization of Natural Variants of HIV-1 Nef Gene from North India and its Functional Implication in Down-Regulation of MHC-I and CD-4.

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HIV-1 interactions

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Protein interactions

Protein	Gene	Interaction	Pubs
AP2-associated protein kinase 1 isoform 1	AAK1	requires	PubMed
alanyl-tRNA editing protein Aarsd1	AARSD1	interacts with	PubMed
serine/threonine-protein kinase LMTK1 isoform 2	AATK	interacts with	PubMed
phospholipid-transporting ATPase ABCA1	ABCA1	downregulates	PubMed
	ABCA1	inhibits	PubMed
	ABCA1	interacts with	PubMed
	ABCA1	inhibited by	PubMed
	ABCA1	interacts with	PubMed
	ABCA1	downregulates	PubMed
arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1	ACAP1	requires	PubMed
acetylcholinesterase isoform E4-E6 precursor	ACHE	interacts with	PubMed
	ACHE	upregulates	PubMed
	ACHE	co-localizes with	PubMed
ATP-citrate synthase isoform 1	ACLY	complexes with	PubMed
acyl-coenzyme A thioesterase 8	ACOT8	interacts with	PubMed
	ACOT8	interacts with	PubMed
	ACOT8	binds	PubMed
	ACOT8	binds	PubMed
fatty acid CoA ligase Acsl3	ACSL3	complexes with	PubMed
actin, alpha skeletal muscle	ACTA1	relocalizes	PubMed
	ACTA1	enhances	PubMed
	ACTA1	downregulates	PubMed
	ACTA1	co-localizes with	PubMed
	ACTA1	inhibits	PubMed
	ACTA1	interacts with	PubMed
	ACTA1	inhibits	PubMed
	ACTA1	disrupts	PubMed
actin, aortic smooth muscle isoform 1	ACTA2	relocalizes	PubMed
	ACTA2	co-localizes with	PubMed
	ACTA2	downregulates	PubMed
	ACTA2	inhibits	PubMed
	ACTA2	inhibits	PubMed
actin, cytoplasmic 1	ACTB	relocalizes	PubMed
	ACTB	co-localizes with	PubMed
	ACTB	complexes with	PubMed
	ACTB	downregulates	PubMed
	ACTB	inhibits	PubMed
	ACTB	inhibits	PubMed
	ACTB	interacts with	PubMed
	ACTB	interacts with	PubMed
	ACTB	induces rearrangement of	PubMed
	ACTB	associates with	PubMed
actin, alpha cardiac muscle 1 isoform 1	ACTC1	downregulates	PubMed
	ACTC1	inhibits	PubMed
	ACTC1	inhibits	PubMed
actin, cytoplasmic 2	ACTG1	downregulates	PubMed
	ACTG1	inhibits	PubMed
	ACTG1	inhibits	PubMed
	ACTG1	induces rearrangement of	PubMed
	ACTG1	associates with	PubMed
actin, gamma-enteric smooth muscle isoform 1 precursor	ACTG2	downregulates	PubMed
	ACTG2	inhibits	PubMed
	ACTG2	inhibits	PubMed
disintegrin and metalloproteinase domain-containing protein 10 isoform 1 preproprotein	ADAM10	associates with	PubMed
disintegrin and metalloproteinase domain-containing protein 17 isoform 1 preproprotein	ADAM17	incorporates	PubMed
	ADAM17	activates	PubMed
	ADAM17	interacts with	PubMed
	ADAM17	interacts with	PubMed
	ADAM17	activates	PubMed
double-stranded RNA-specific adenosine deaminase isoform a	ADAR	complexes with	PubMed
	ADAR	upregulates	PubMed
adenylate cyclase type 1 isoform 1	ADCY1	activates	PubMed
adenylate cyclase type 2	ADCY2	activates	PubMed
adenylate cyclase type 3 isoform 2	ADCY3	activates	PubMed
adenylate cyclase type 4	ADCY4	activates	PubMed
adenylate cyclase type 5 isoform 1	ADCY5	activates	PubMed
adenylate cyclase type 6 isoform 1	ADCY6	activates	PubMed
adenylate cyclase type 7 isoform 1	ADCY7	activates	PubMed
adenylate cyclase type 8	ADCY8	activates	PubMed
adenylate cyclase type 9	ADCY9	activates	PubMed
arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform 2	AGAP1	requires	PubMed
arf-GAP domain and FG repeat-containing protein 2	AGFG2	requires	PubMed
protein argonaute-2 isoform 1	AGO2	inhibits	PubMed
	AGO2	interacts with	PubMed
	AGO2	co-localizes with	PubMed
apoptosis-inducing factor 1, mitochondrial isoform AIF precursor	AIFM1	complexes with	PubMed
RAC-alpha serine/threonine-protein kinase	AKT1	upregulates	PubMed
	AKT1	interacts with	PubMed
	AKT1	increases phosphorylation of	PubMed
	AKT1	activates	PubMed
	AKT1	activates	PubMed
	AKT1	activates	PubMed
	AKT1	interacts with	PubMed
	AKT1	activates	PubMed
	AKT1	activates	PubMed
	AKT1	induces phosphorylation of	PubMed
	AKT1	decreases phosphorylation of	PubMed
RAC-beta serine/threonine-protein kinase isoform 1	AKT2	activates	PubMed
	AKT2	interacts with	PubMed
	AKT2	interacts with	PubMed
	AKT2	activates	PubMed
	AKT2	activates	PubMed
	AKT2	induces phosphorylation of	PubMed
	AKT2	decreases phosphorylation of	PubMed
RAC-gamma serine/threonine-protein kinase isoform 1	AKT3	activates	PubMed
	AKT3	interacts with	PubMed
	AKT3	interacts with	PubMed
	AKT3	activates	PubMed
	AKT3	activates	PubMed
	AKT3	induces phosphorylation of	PubMed
	AKT3	decreases phosphorylation of	PubMed
delta-1-pyrroline-5-carboxylate synthase isoform 1	ALDH18A1	complexes with	PubMed
ALK tyrosine kinase receptor isoform 1 precursor	ALK	interacts with	PubMed
	ALK	interacts with	PubMed
	ALK	interacts with	PubMed
	ALK	upregulates	PubMed
THO complex subunit 4	ALYREF	complexes with	PubMed
annexin A2 isoform 2	ANXA2	co-localizes with	PubMed
AP-1 complex subunit beta-1 isoform a	AP1B1	inhibits	PubMed
	AP1B1	activates	PubMed
	AP1B1	stabilizes	PubMed
	AP1B1	binds	PubMed
	AP1B1	interacts with	PubMed
AP-1 complex subunit gamma-1 isoform b	AP1G1	inhibits	PubMed
	AP1G1	interacts with	PubMed
	AP1G1	activates	PubMed
	AP1G1	interacts with	PubMed
	AP1G1	interacts with	PubMed
	AP1G1	binds	PubMed
	AP1G1	stabilizes	PubMed
AP-1 complex subunit gamma-like 2 isoform 1	AP1G2	inhibits	PubMed
	AP1G2	activates	PubMed
	AP1G2	stabilizes	PubMed
	AP1G2	binds	PubMed
	AP1G2	interacts with	PubMed
AP-1 complex subunit mu-1 isoform 2	AP1M1	interacts with	PubMed
	AP1M1	interacts with	PubMed
	AP1M1	interacts with	PubMed
	AP1M1	inhibits	PubMed
	AP1M1	complexes with	PubMed
	AP1M1	interacts with	PubMed
	AP1M1	complexes with	PubMed
	AP1M1	activates	PubMed
	AP1M1	interacts with	PubMed
	AP1M1	interacts with	PubMed
	AP1M1	interacts with	PubMed
	AP1M1	interacts with	PubMed
	AP1M1	binds	PubMed
	AP1M1	binds	PubMed
	AP1M1	stabilizes	PubMed
AP-1 complex subunit sigma-1A	AP1S1	inhibits	PubMed
	AP1S1	activates	PubMed
	AP1S1	stabilizes	PubMed
	AP1S1	binds	PubMed
	AP1S1	interacts with	PubMed
AP-1 complex subunit sigma-2 isoform 2	AP1S2	inhibits	PubMed
	AP1S2	activates	PubMed
	AP1S2	binds	PubMed
	AP1S2	stabilizes	PubMed
	AP1S2	interacts with	PubMed
AP-1 complex subunit sigma-3	AP1S3	requires	PubMed
	AP1S3	inhibits	PubMed
	AP1S3	stabilizes	PubMed
	AP1S3	binds	PubMed
	AP1S3	interacts with	PubMed
AP-2 complex subunit alpha-1 isoform 1	AP2A1	binds	PubMed
	AP2A1	binds	PubMed
	AP2A1	binds	PubMed
	AP2A1	binds	PubMed
	AP2A1	inhibited by	PubMed
	AP2A1	binds	PubMed
AP-2 complex subunit alpha-2 isoform 2	AP2A2	requires	PubMed
	AP2A2	inhibited by	PubMed
	AP2A2	binds	PubMed
	AP2A2	binds	PubMed
AP-2 complex subunit beta isoform b	AP2B1	interacts with	PubMed
	AP2B1	binds	PubMed
	AP2B1	co-localizes with	PubMed
	AP2B1	co-localizes with	PubMed
AP-2 complex subunit mu isoform a	AP2M1	interacts with	PubMed
	AP2M1	requires	PubMed
	AP2M1	complexes with	PubMed
	AP2M1	interacts with	PubMed
	AP2M1	requires	PubMed
AP-2 complex subunit sigma isoform AP17	AP2S1	binds	PubMed
	AP2S1	binds	PubMed
	AP2S1	binds	PubMed
AP-3 complex subunit delta-1 isoform 2	AP3D1	complexes with	PubMed
	AP3D1	co-localizes with	PubMed
	AP3D1	binds	PubMed
AP-3 complex subunit mu-1 isoform a	AP3M1	interacts with	PubMed
AP-3 complex subunit sigma-1 isoform 1	AP3S1	complexes with	PubMed
apolipoprotein A-I isoform 1 preproprotein	APOA1	inhibits	PubMed
	APOA1	inhibits	PubMed
apolipoprotein L1 isoform a precursor	APOL1	downregulated by	PubMed
ADP-ribosylation factor 1	ARF1	requires	PubMed
	ARF1	complexes with	PubMed
	ARF1	binds	PubMed
ADP-ribosylation factor 4	ARF4	complexes with	PubMed
ADP-ribosylation factor 5	ARF5	complexes with	PubMed
ADP-ribosylation factor 6	ARF6	complexes with	PubMed
	ARF6	inhibited by	PubMed
	ARF6	activates	PubMed
	ARF6	regulated by	PubMed
ADP-ribosylation factor GTPase-activating protein 2 isoform 1	ARFGAP2	requires	PubMed
rho GDP-dissociation inhibitor 1 isoform a	ARHGDIA	downregulates	PubMed
rho guanine nucleotide exchange factor 6 isoform 1	ARHGEF6	induces phosphorylation of	PubMed
rho guanine nucleotide exchange factor 7 isoform a	ARHGEF7	induces complex with	PubMed
ADP-ribosylation factor-like protein 1 isoform 1	ARL1	complexes with	PubMed
ADP-ribosylation factor-like protein 5A isoform 1	ARL5A	requires	PubMed
ADP-ribosylation factor-like protein 5B	ARL5B	requires	PubMed
actin-related protein 2/3 complex subunit 4 isoform a	ARPC4	complexes with	PubMed
cyclic AMP-dependent transcription factor ATF-2 isoform 1	ATF2	interacts with	PubMed
	ATF2	inhibits	PubMed
cyclic AMP-dependent transcription factor ATF-3 isoform 1	ATF3	upregulates	PubMed
autophagy-related protein 16-1 isoform 2	ATG16L1	interacts with	PubMed
protein Atg16l2 isoform 1	ATG16L2	interacts with	PubMed
sodium/potassium-transporting ATPase subunit alpha-1 isoform a	ATP1A1	complexes with	PubMed
ATP synthase subunit alpha, mitochondrial isoform a precursor	ATP5F1A	complexes with	PubMed
ATP synthase subunit gamma, mitochondrial isoform H (heart) precursor	ATP5F1C	complexes with	PubMed
ATP synthase subunit O, mitochondrial precursor	ATP5PO	complexes with	PubMed
V-type proton ATPase subunit S1 precursor	ATP6AP1	requires	PubMed
V-type proton ATPase subunit d 1	ATP6V0D1	complexes with	PubMed
V-type proton ATPase subunit B, kidney isoform	ATP6V1B1	requires	PubMed
V-type proton ATPase subunit H isoform 2	ATP6V1H	cooperates with	PubMed
	ATP6V1H	binds	PubMed
all-trans retinoic acid-induced differentiation factor isoform a	ATRAID	interacts with	PubMed
beta-2-microglobulin precursor	B2M	downregulates	PubMed
beta-1,4-glucuronyltransferase 1	B4GAT1	interacts with	PubMed
bcl2-associated agonist of cell death	BAD	induces phosphorylation of	PubMed
B-cell receptor-associated protein 31 isoform b	BCAP31	interacts with	PubMed
apoptosis regulator Bcl-2 isoform alpha	BCL2	upregulates	PubMed
	BCL2	downregulates	PubMed
bcl-2-like protein 1 isoform Bcl-X(L)	BCL2L1	downregulates	PubMed
	BCL2L1	upregulates	PubMed
beclin-1 isoform a	BECN1	interacts with	PubMed
	BECN1	requires	PubMed
	BECN1	interacts with	PubMed
bone morphogenetic protein receptor type-1A isoform 3 precursor	BMPR1A	downregulates	PubMed
bone morphogenetic protein receptor type-1B isoform b precursor	BMPR1B	downregulates	PubMed
bone morphogenetic protein receptor type-2 precursor	BMPR2	downregulates	PubMed
cytoplasmic tyrosine-protein kinase BMX isoform 1	BMX	interacts with	PubMed
bone marrow stromal antigen 2 precursor	BST2	downregulates	PubMed
	BST2	downregulates	PubMed
	BST2	binds	PubMed
	BST2	downregulates	PubMed
	BST2	downregulates	PubMed
	BST2	downregulates	PubMed
	BST2	interacts with	PubMed
	BST2	upregulates	PubMed
	BST2	upregulates	PubMed
tyrosine-protein kinase BTK isoform 1	BTK	interacts with	PubMed
complement C3 preproprotein	C3	upregulates	PubMed
C5a anaphylatoxin chemotactic receptor 1	C5AR1	upregulates	PubMed
multifunctional protein CAD isoform 1	CAD	complexes with	PubMed
calmodulin-1 isoform 2	CALM1	interacts with	PubMed
	CALM1	requires	PubMed
	CALM1	binds	PubMed
	CALM1	interacts with	PubMed
calmodulin-2 isoform 2	CALM2	interacts with	PubMed
	CALM2	requires	PubMed
	CALM2	interacts with	PubMed
calmodulin-3 isoform 1	CALM3	interacts with	PubMed
	CALM3	requires	PubMed
	CALM3	interacts with	PubMed
calmodulin-regulated spectrin-associated protein 3 isoform 1	CAMSAP3	affected by	PubMed
calnexin isoform d precursor	CANX	interacts with	PubMed
	CANX	interacts with	PubMed
	CANX	complexes with	PubMed
caprin-1 isoform 1	CAPRIN1	complexes with	PubMed
caspase-3 isoform a preproprotein	CASP3	activates	PubMed
	CASP3	inactivates	PubMed
	CASP3	requires	PubMed
caspase-8 isoform 1 precursor	CASP8	inactivates	PubMed
caspase-9 isoform alpha precursor	CASP9	inhibits	PubMed
	CASP9	upregulates	PubMed
caveolin-1 isoform alpha	CAV1	induces phosphorylation of	PubMed
	CAV1	redistributes	PubMed
	CAV1	interacts with	PubMed
E3 ubiquitin-protein ligase CBL	CBL	induces complex with	PubMed
	CBL	induces phosphorylation of	PubMed
C-C motif chemokine 19 precursor	CCL19	inhibits	PubMed
C-C motif chemokine 2 precursor	CCL2	induces release of	PubMed
	CCL2	inhibits	PubMed
	CCL2	upregulates	PubMed
C-C motif chemokine 20 isoform 1 precursor	CCL20	upregulates	PubMed
C-C motif chemokine 24 precursor	CCL24	upregulates	PubMed
C-C motif chemokine 3 precursor	CCL3	upregulates	PubMed
	CCL3	upregulates	PubMed
	CCL3	inhibits	PubMed
	CCL3	upregulates	PubMed
C-C motif chemokine 3-like 1 precursor	CCL3L1	upregulates	PubMed
C-C motif chemokine 4 precursor	CCL4	upregulates	PubMed
	CCL4	upregulates	PubMed
	CCL4	interacts with	PubMed
	CCL4	interacts with	PubMed
	CCL4	upregulates	PubMed
	CCL4	downregulates	PubMed
	CCL4	upregulates	PubMed
C-C motif chemokine 5 isoform 1 precursor	CCL5	incorporates	PubMed
	CCL5	upregulates	PubMed
	CCL5	upregulates	PubMed
	CCL5	upregulates	PubMed
	CCL5	upregulates	PubMed
	CCL5	upregulates	PubMed
	CCL5	downregulates	PubMed
	CCL5	upregulates	PubMed
G1/S-specific cyclin-D1	CCND1	upregulates	PubMed
	CCND1	upregulates	PubMed
G1/S-specific cyclin-E1 isoform 1	CCNE1	downregulates	PubMed
cyclin-K	CCNK	interacts with	PubMed
	CCNK	interacts with	PubMed
C-C chemokine receptor type 1	CCR1	downregulates	PubMed
C-C chemokine receptor type 2 isoform A	CCR2	downregulates	PubMed
C-C chemokine receptor type 3 isoform 1	CCR3	downregulates	PubMed
C-C chemokine receptor type 5	CCR5	downregulates	PubMed
	CCR5	downregulates	PubMed
	CCR5	downregulates	PubMed
C-C chemokine receptor type 7 isoform a precursor	CCR7	downregulates	PubMed
	CCR7	upregulates	PubMed
C-C chemokine receptor type 9 isoform B	CCR9	downregulates	PubMed
T-complex protein 1 subunit beta isoform 1	CCT2	complexes with	PubMed
T-complex protein 1 subunit delta isoform a	CCT4	complexes with	PubMed
CD109 antigen isoform 1 preproprotein	CD109	downregulates	PubMed
monocyte differentiation antigen CD14 precursor	CD14	downregulates	PubMed
	CD14	upregulates	PubMed
CD151 antigen	CD151	downregulates	PubMed
scavenger receptor cysteine-rich type 1 protein M130 isoform a precursor	CD163	downregulates	PubMed
sialomucin core protein 24 isoform 1 precursor	CD164	downregulates	PubMed
T-cell surface glycoprotein CD1a isoform 1 precursor	CD1A	interacts with	PubMed
	CD1A	downregulates	PubMed
antigen-presenting glycoprotein CD1d isoform 1 precursor	CD1D	downregulates	PubMed
	CD1D	inhibits	PubMed
	CD1D	downregulates	PubMed
	CD1D	downregulates	PubMed
CD209 antigen isoform 1	CD209	interacts with	PubMed
	CD209	upregulates	PubMed
	CD209	upregulates	PubMed
	CD209	upregulates	PubMed
B-cell receptor CD22 isoform 1 precursor	CD22	upregulates	PubMed
CD226 antigen isoform a precursor	CD226	interacts with	PubMed
T-cell surface glycoprotein CD3 zeta chain isoform 1 precursor	CD247	upregulates	PubMed
	CD247	interacts with	PubMed
	CD247	co-localizes with	PubMed
	CD247	interacts with	PubMed
CD27 antigen precursor	CD27	downregulates	PubMed
T-cell-specific surface glycoprotein CD28 isoform 1 precursor	CD28	downregulates	PubMed
	CD28	downregulates	PubMed
	CD28	co-localizes with	PubMed
	CD28	downregulates	PubMed
	CD28	downregulates	PubMed
	CD28	upregulates	PubMed
	CD28	downregulates	PubMed
CD320 antigen isoform 1 precursor	CD320	interacts with	PubMed
platelet glycoprotein 4 isoform 1	CD36	downregulates	PubMed
	CD36	downregulates	PubMed
leukocyte antigen CD37 isoform A	CD37	relocalizes	PubMed
	CD37	downregulates	PubMed
T-cell surface glycoprotein CD3 delta chain isoform A precursor	CD3D	downregulates	PubMed
	CD3D	interacts with	PubMed
T-cell surface glycoprotein CD3 epsilon chain precursor	CD3E	antagonizes	PubMed
	CD3E	downregulates	PubMed
	CD3E	interacts with	PubMed
	CD3E	interacts with	PubMed
T-cell surface glycoprotein CD3 gamma chain precursor	CD3G	downregulates	PubMed
	CD3G	downregulates	PubMed
	CD3G	interacts with	PubMed
	CD3G	cooperates with	PubMed
	CD3G	interacts with	PubMed
T-cell surface glycoprotein CD4 isoform 1 precursor	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	interacts with	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	degrades	PubMed
	CD4	downregulates	PubMed
	CD4	interacts with	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	enhances	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	interacts with	PubMed
	CD4	downregulates	PubMed
	CD4	interacts with	PubMed
	CD4	degrades	PubMed
	CD4	complexes with	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	modulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	binds	PubMed
	CD4	binds	PubMed
	CD4	binds	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	interacts with	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	degrades	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
	CD4	downregulates	PubMed
CD40 ligand	CD40LG	upregulates	PubMed
	CD40LG	inhibits	PubMed
membrane cofactor protein isoform 1 precursor	CD46	downregulates	PubMed
CD48 antigen isoform 1 precursor	CD48	downregulates	PubMed
T-cell surface glycoprotein CD5 isoform 1 precursor	CD5	interacts with	PubMed
leukocyte surface antigen CD53 isoform 1	CD53	relocalizes	PubMed
	CD53	downregulates	PubMed
lymphocyte function-associated antigen 3 isoform 1	CD58	upregulates	PubMed
CD59 glycoprotein preproprotein	CD59	enhances release of	PubMed
CD63 antigen isoform A	CD63	enhances release of	PubMed
	CD63	downregulates	PubMed
	CD63	co-localizes with	PubMed
	CD63	co-localizes with	PubMed
	CD63	co-localizes with	PubMed
early activation antigen CD69	CD69	enhances	PubMed
	CD69	enhances	PubMed
	CD69	upregulates	PubMed
	CD69	downregulates	PubMed
	CD69	downregulates	PubMed
T-cell antigen CD7 precursor	CD7	downregulates	PubMed
HLA class II histocompatibility antigen gamma chain isoform b	CD74	upregulates	PubMed
	CD74	upregulates	PubMed
	CD74	upregulates	PubMed
	CD74	upregulates	PubMed
	CD74	upregulates	PubMed
	CD74	upregulates	PubMed
	CD74	upregulates	PubMed
	CD74	upregulates	PubMed
	CD74	upregulates	PubMed
T-lymphocyte activation antigen CD80 precursor	CD80	upregulates	PubMed
	CD80	binds	PubMed
	CD80	downregulates	PubMed
	CD80	interacts with	PubMed
	CD80	binds	PubMed
	CD80	downregulates	PubMed
	CD80	downregulates	PubMed
CD81 antigen isoform 1	CD81	interacts with	PubMed
	CD81	downregulates	PubMed
	CD81	co-localizes with	PubMed
CD83 antigen isoform a precursor	CD83	downregulates	PubMed
	CD83	upregulates	PubMed
T-lymphocyte activation antigen CD86 isoform 1 precursor	CD86	downregulates	PubMed
	CD86	binds	PubMed
	CD86	binds	PubMed
	CD86	downregulates	PubMed
	CD86	downregulates	PubMed
T-cell surface glycoprotein CD8 alpha chain isoform 1 precursor	CD8A	co-localizes with	PubMed
	CD8A	downregulates	PubMed
	CD8A	downregulates	PubMed
T-cell surface glycoprotein CD8 beta chain isoform 2 precursor	CD8B	downregulates	PubMed
	CD8B	downregulates	PubMed
	CD8B	downregulates	PubMed
	CD8B	co-localizes with	PubMed
cell division control protein 42 homolog isoform 1 precursor	CDC42	enhances	PubMed
	CDC42	interacts with	PubMed
	CDC42	inhibits	PubMed
	CDC42	upregulates	PubMed
cell division cycle 5-like protein	CDC5L	complexes with	PubMed
CDP-diacylglycerol--inositol 3-phosphatidyltransferase isoform 1	CDIPT	complexes with	PubMed
cyclin-dependent kinase 13 isoform 1	CDK13	upregulated by	PubMed
cyclin-dependent kinase 9	CDK9	interacts with	PubMed
	CDK9	upregulates	PubMed
	CDK9	interacts with	PubMed
threonylcarbamoyladenosine tRNA methylthiotransferase	CDKAL1	interacts with	PubMed
cyclin-dependent kinase inhibitor 1 isoform 1	CDKN1A	upregulates	PubMed
cyclin-dependent kinase inhibitor 2A isoform p16INK4a	CDKN2A	interacts with	PubMed
CCAAT/enhancer-binding protein alpha isoform a	CEBPA	interacts with	PubMed
CCAAT/enhancer-binding protein gamma	CEBPG	interacts with	PubMed
cofilin-1	CFL1	induces phosphorylation of	PubMed
	CFL1	induces phosphorylation of	PubMed
	CFL1	induces phosphorylation of	PubMed
cofilin-2 isoform 1	CFL2	induces phosphorylation of	PubMed
charged multivesicular body protein 7 isoform 1	CHMP7	requires	PubMed
N-chimaerin isoform 1	CHN1	interacts with	PubMed
inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1	CHUK	induces phosphorylation of	PubMed
	CHUK	activates	PubMed
	CHUK	induces phosphorylation of	PubMed
	CHUK	induces phosphorylation of	PubMed
	CHUK	induces phosphorylation of	PubMed
claudin-10 isoform b	CLDN10	interacts with	PubMed
clathrin interactor 1 isoform 2	CLINT1	requires	PubMed
battenin isoform a	CLN3	requires	PubMed
clathrin light chain A isoform a	CLTA	complexes with	PubMed
	CLTA	complexes with	PubMed
	CLTA	interacts with	PubMed
clathrin light chain B isoform a	CLTB	complexes with	PubMed
	CLTB	complexes with	PubMed
	CLTB	interacts with	PubMed
clathrin heavy chain 1 isoform 1	CLTC	complexes with	PubMed
	CLTC	complexes with	PubMed
	CLTC	interacts with	PubMed
	CLTC	interacts with	PubMed
clathrin heavy chain 2 isoform 1	CLTCL1	requires	PubMed
coatomer subunit alpha isoform 2	COPA	complexes with	PubMed
coatomer subunit beta	COPB1	cooperates with	PubMed
	COPB1	cooperates with	PubMed
	COPB1	interacts with	PubMed
	COPB1	binds	PubMed
	COPB1	co-localizes with	PubMed
coatomer subunit beta' isoform 1	COPB2	interacts with	PubMed
coatomer subunit zeta-1 isoform 1	COPZ1	complexes with	PubMed
copine-3	CPNE3	complexes with	PubMed
cleavage and polyadenylation specificity factor subunit 1	CPSF1	complexes with	PubMed
cleavage and polyadenylation specificity factor subunit 7 isoform 1	CPSF7	complexes with	PubMed
macrophage colony-stimulating factor 1 receptor isoform a precursor	CSF1R	downregulates	PubMed
	CSF1R	deglycosylates	PubMed
	CSF1R	disrupts	PubMed
	CSF1R	inhibits	PubMed
granulocyte-macrophage colony-stimulating factor precursor	CSF2	incorporates	PubMed
	CSF2	upregulates	PubMed
	CSF2	interacts with	PubMed
cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor	CTLA4	downregulates	PubMed
	CTLA4	downregulates	PubMed
	CTLA4	co-localizes with	PubMed
	CTLA4	upregulates	PubMed
catenin beta-1 isoform 1	CTNNB1	binds	PubMed
	CTNNB1	interacts with	PubMed
cathepsin D preproprotein	CTSD	induces release of	PubMed
growth-regulated alpha protein precursor	CXCL1	incorporates	PubMed
C-X-C motif chemokine 10 precursor	CXCL10	upregulates	PubMed
stromal cell-derived factor 1 isoform beta precursor	CXCL12	inhibits	PubMed
	CXCL12	modulates	PubMed
	CXCL12	inhibits	PubMed
interleukin-8 isoform 1 precursor	CXCL8	induces	PubMed
	CXCL8	induces	PubMed
	CXCL8	induces	PubMed
	CXCL8	induces release of	PubMed
	CXCL8	upregulates	PubMed
C-X-C chemokine receptor type 1	CXCR1	downregulates	PubMed
C-X-C chemokine receptor type 2	CXCR2	downregulates	PubMed
C-X-C chemokine receptor type 3 isoform 1	CXCR3	downregulates	PubMed
	CXCR3	interacts with	PubMed
C-X-C chemokine receptor type 4 isoform b	CXCR4	downregulates	PubMed
	CXCR4	downregulates	PubMed
	CXCR4	downregulates	PubMed
	CXCR4	co-localizes with	PubMed
	CXCR4	downregulates	PubMed
	CXCR4	enhances	PubMed
	CXCR4	downregulates	PubMed
	CXCR4	interacts with	PubMed
	CXCR4	interacts with	PubMed
	CXCR4	upregulates	PubMed
	CXCR4	downregulates	PubMed
	CXCR4	modulates	PubMed
	CXCR4	inhibits	PubMed
	CXCR4	interacts with	PubMed
	CXCR4	interacts with	PubMed
C-X-C chemokine receptor type 5 isoform 1	CXCR5	downregulates	PubMed
cytochrome b5 type B	CYB5B	interacts with	PubMed
cytochrome b-245 light chain	CYBA	associates with	PubMed
cytochrome b-245 heavy chain	CYBB	requires	PubMed
cytochrome c	CYCS	interacts with	PubMed
lanosterol 14-alpha demethylase isoform 1	CYP51A1	upregulates	PubMed
disabled homolog 2 isoform 1	DAB2	requires	PubMed
aspartate--tRNA ligase, cytoplasmic isoform 1	DARS1	complexes with	PubMed
dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit precursor	DDOST	complexes with	PubMed
ATP-dependent RNA helicase DDX1	DDX1	complexes with	PubMed
probable ATP-dependent RNA helicase DDX17 isoform 1 precursor	DDX17	complexes with	PubMed
nucleolar RNA helicase 2 isoform 1	DDX21	complexes with	PubMed
probable ATP-dependent RNA helicase DDX23	DDX23	complexes with	PubMed
probable ATP-dependent RNA helicase DDX27 isoform 2	DDX27	complexes with	PubMed
spliceosome RNA helicase DDX39B	DDX39B	complexes with	PubMed
ATP-dependent RNA helicase DDX3X isoform 1	DDX3X	complexes with	PubMed
probable ATP-dependent RNA helicase DDX5 isoform a	DDX5	complexes with	PubMed
7-dehydrocholesterol reductase isoform 1	DHCR7	complexes with	PubMed
ATP-dependent RNA helicase DHX15	DHX15	complexes with	PubMed
ATP-dependent RNA helicase DHX30 isoform 2	DHX30	complexes with	PubMed
ATP-dependent RNA helicase A	DHX9	regulated by	PubMed
	DHX9	complexes with	PubMed
dnaJ homolog subfamily B member 1 isoform 1	DNAJB1	upregulates	PubMed
	DNAJB1	interacts with	PubMed
	DNAJB1	interacts with	PubMed
dynamin-2 isoform 3	DNM2	complexes with	PubMed
	DNM2	requires	PubMed
	DNM2	binds	PubMed
	DNM2	regulated by	PubMed
dedicator of cytokinesis protein 2	DOCK2	interacts with	PubMed
dermatopontin precursor	DPT	upregulates	PubMed
developmentally-regulated GTP-binding protein 1	DRG1	complexes with	PubMed
dual specificity protein phosphatase 1	DUSP1	enhances	PubMed
endothelin-1 isoform 1 preproprotein	EDN1	inhibits	PubMed
polycomb protein EED isoform a	EED	inhibits	PubMed
	EED	binds	PubMed
	EED	relocalizes	PubMed
elongation factor 1-alpha 1	EEF1A1	complexes with	PubMed
	EEF1A1	complexes with	PubMed
	EEF1A1	binds	PubMed
	EEF1A1	interacts with	PubMed
	EEF1A1	complexes with	PubMed
elongation factor 1-delta isoform 1	EEF1D	complexes with	PubMed
	EEF1D	interacts with	PubMed
elongation factor 1-gamma	EEF1G	interacts with	PubMed
	EEF1G	complexes with	PubMed
EH domain-containing protein 4	EHD4	cooperates with	PubMed
interferon-induced, double-stranded RNA-activated protein kinase isoform a	EIF2AK2	regulated by	PubMed
	EIF2AK2	interacts with	PubMed
eukaryotic translation initiation factor 3 subunit A	EIF3A	complexes with	PubMed
eukaryotic translation initiation factor 3 subunit D	EIF3D	complexes with	PubMed
eukaryotic translation initiation factor 3 subunit E	EIF3E	complexes with	PubMed
eukaryotic initiation factor 4A-I isoform 1	EIF4A1	complexes with	PubMed
eukaryotic initiation factor 4A-III isoform 1	EIF4A3	complexes with	PubMed
eukaryotic translation initiation factor 5A-1 isoform B	EIF5A	downregulates	PubMed
ELAV-like protein 1	ELAVL1	complexes with	PubMed
ETS domain-containing protein Elk-1 isoform a	ELK1	induces phosphorylation of	PubMed
engulfment and cell motility protein 1 isoform 1	ELMO1	interacts with	PubMed
elongin-A	ELOA	upregulates	PubMed
alpha-enolase isoform 1	ENO1	downregulates	PubMed
	ENO1	complexes with	PubMed
endosome-associated-trafficking regulator 1 isoform 2	ENTR1	requires	PubMed
endothelial PAS domain-containing protein 1	EPAS1	upregulates	PubMed
ephrin type-B receptor 2 isoform 2 precursor	EPHB2	inactivates	PubMed
bifunctional glutamate/proline--tRNA ligase	EPRS1	complexes with	PubMed
epidermal growth factor receptor substrate 15 isoform A	EPS15	requires	PubMed
endoplasmic reticulum-Golgi intermediate compartment protein 1	ERGIC1	interacts with	PubMed
electron transfer flavoprotein subunit beta isoform 1	ETFB	complexes with	PubMed
exocyst complex component 1 isoform 1	EXOC1	interacts with	PubMed
	EXOC1	binds	PubMed
exocyst complex component 2	EXOC2	inhibited by	PubMed
	EXOC2	interacts with	PubMed
	EXOC2	interacts with	PubMed
	EXOC2	interacts with	PubMed
	EXOC2	regulated by	PubMed
	EXOC2	binds	PubMed
exocyst complex component 3	EXOC3	interacts with	PubMed
	EXOC3	binds	PubMed
exocyst complex component 4 isoform a	EXOC4	inhibited by	PubMed
	EXOC4	interacts with	PubMed
	EXOC4	interacts with	PubMed
	EXOC4	binds	PubMed
exocyst complex component 6 isoform a	EXOC6	binds	PubMed
ezrin	EZR	enhances	PubMed
tumor necrosis factor receptor superfamily member 6 isoform 1 precursor	FAS	incorporates	PubMed
	FAS	upregulates	PubMed
	FAS	inhibits	PubMed
	FAS	inhibits	PubMed
	FAS	upregulates	PubMed
tumor necrosis factor ligand superfamily member 6 isoform 1	FASLG	upregulates	PubMed
	FASLG	upregulates	PubMed
	FASLG	upregulates	PubMed
	FASLG	upregulates	PubMed
	FASLG	upregulates	PubMed
	FASLG	upregulates	PubMed
fatty acid synthase	FASN	complexes with	PubMed
low affinity immunoglobulin epsilon Fc receptor isoform a	FCER2	induces release of	PubMed
high affinity immunoglobulin gamma Fc receptor I isoform 2 precursor	FCGR1A	downregulates	PubMed
high affinity immunoglobulin gamma Fc receptor IB isoform 1 precursor	FCGR1BP	downregulates	PubMed
low affinity immunoglobulin gamma Fc region receptor II-a isoform 2 precursor	FCGR2A	downregulates	PubMed
low affinity immunoglobulin gamma Fc region receptor II-b isoform 1 precursor	FCGR2B	downregulates	PubMed
low affinity immunoglobulin gamma Fc region receptor III-A isoform a	FCGR3A	antagonizes	PubMed
fibroblast growth factor 2 isoform 34 kDa	FGF2	upregulates	PubMed
pre-mRNA 3'-end-processing factor FIP1 isoform 1	FIP1L1	complexes with	PubMed
filamin-A isoform 1	FLNA	complexes with	PubMed
filamin-B isoform 2	FLNB	interacts with	PubMed
vascular endothelial growth factor receptor 1 isoform 1 precursor	FLT1	upregulates	PubMed
fibronectin isoform 1 precursor	FN1	upregulates	PubMed
protein c-Fos	FOS	interacts with	PubMed
	FOS	activates	PubMed
	FOS	downregulates	PubMed
ferritin heavy chain	FTH1	induces release of	PubMed
ferritin light chain	FTL	induces release of	PubMed
tyrosine-protein kinase Fyn isoform a	FYN	binds	PubMed
	FYN	binds	PubMed
	FYN	binds	PubMed
gamma-aminobutyric acid receptor-associated protein	GABARAP	downregulates	PubMed
glyceraldehyde-3-phosphate dehydrogenase isoform 1	GAPDH	complexes with	PubMed
GAS2-like protein 1 isoform a	GAS2L1	requires	PubMed
erythroid transcription factor	GATA1	binds	PubMed
trans-acting T-cell-specific transcription factor GATA-3 isoform 2	GATA3	binds	PubMed
guanylate-binding protein 5 isoform 1	GBP5	antagonizes	PubMed
GRIP and coiled-coil domain-containing protein 2	GCC2	binds	PubMed
glial fibrillary acidic protein isoform 1	GFAP	downregulates	PubMed
	GFAP	co-localizes with	PubMed
	GFAP	upregulates	PubMed
ADP-ribosylation factor-binding protein GGA1 isoform 1	GGA1	requires	PubMed
ADP-ribosylation factor-binding protein GGA2	GGA2	requires	PubMed
guanine nucleotide-binding protein G(i) subunit alpha-2 isoform 1	GNAI2	degrades	PubMed
	GNAI2	interacts with	PubMed
guanine nucleotide-binding protein G(o) subunit alpha isoform a	GNAO1	binds	PubMed
golgin subfamily A member 2	GOLGA2	requires	PubMed
	GOLGA2	relocalizes	PubMed
golgin subfamily A member 4 isoform 2	GOLGA4	requires	PubMed
Golgi reassembly-stacking protein 1 isoform 1	GORASP1	activates	PubMed
neuronal membrane glycoprotein M6-a isoform 1	GPM6A	interacts with	PubMed
neuronal membrane glycoprotein M6-b isoform 3	GPM6B	interacts with	PubMed
growth factor receptor-bound protein 2 isoform 1	GRB2	upregulates	PubMed
glycogen synthase kinase-3 alpha	GSK3A	induces phosphorylation of	PubMed
glycogen synthase kinase-3 beta isoform 1	GSK3B	induces phosphorylation of	PubMed
glycophorin-A isoform 1 precursor	GYPA	downregulates	PubMed
granzyme A precursor	GZMA	upregulates	PubMed
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 isoform 1	HACD3	complexes with	PubMed
tyrosine-protein kinase HCK isoform a	HCK	binds	PubMed
	HCK	activates	PubMed
	HCK	binds	PubMed
	HCK	interacts with	PubMed
	HCK	binds	PubMed
	HCK	binds	PubMed
	HCK	binds	PubMed
	HCK	interacts with	PubMed
	HCK	activates	PubMed
	HCK	activates	PubMed
	HCK	binds	PubMed
	HCK	induces accumulation of	PubMed
	HCK	associates with	PubMed
	HCK	activates	PubMed
	HCK	activates	PubMed
	HCK	complexes with	PubMed
	HCK	stabilized by	PubMed
	HCK	binds	PubMed
	HCK	associates with	PubMed
	HCK	complexes with	PubMed
	HCK	complexes with	PubMed
	HCK	induces accumulation of	PubMed
	HCK	binds	PubMed
	HCK	complexes with	PubMed
	HCK	complexes with	PubMed
	HCK	binds	PubMed
	HCK	binds	PubMed
	HCK	activates	PubMed
	HCK	activates	PubMed
	HCK	activates	PubMed
	HCK	binds	PubMed
	HCK	binds	PubMed
	HCK	binds	PubMed
	HCK	interacts with	PubMed
	HCK	binds	PubMed
	HCK	Inhibits	PubMed
	HCK	activates	PubMed
	HCK	activates	PubMed
	HCK	requires	PubMed
beta-hexosaminidase subunit alpha isoform 1 precursor	HEXA	increases secretion of	PubMed
beta-hexosaminidase subunit beta isoform 1 preproprotein	HEXB	increases secretion of	PubMed
hexosaminidase D isoform 1	HEXD	increases secretion of	PubMed
hereditary hemochromatosis protein isoform 1 precursor	HFE	downregulates	PubMed
	HFE	downregulates	PubMed
hepatocyte growth factor-regulated tyrosine kinase substrate	HGS	co-localizes with	PubMed
huntingtin-interacting protein 1 isoform 1	HIP1	requires	PubMed
HLA class I histocompatibility antigen, A alpha chain isoform A*03:01:01:01 precursor	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	interacts with	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	inhibits	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	complexes with	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	interacts with	PubMed
	HLA-A	interacts with	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	binds	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	inhibits	PubMed
	HLA-A	inhibits	PubMed
	HLA-A	modulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	complexes with	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	interacts with	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	interacts with	PubMed
	HLA-A	degrades	PubMed
	HLA-A	relocalizes	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	modulates	PubMed
	HLA-A	binds	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	binds	PubMed
	HLA-A	co-localizes with	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
	HLA-A	downregulates	PubMed
major histocompatibility complex, class I, B precursor	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	interacts with	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	interacts with	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	modulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	binds	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	complexes with	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	interacts with	PubMed
	HLA-B	degrades	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	modulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	co-localizes with	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
	HLA-B	downregulates	PubMed
HLA class I histocompatibility antigen, C alpha chain precursor	HLA-C	downregulates	PubMed
	HLA-C	downregulates	PubMed
	HLA-C	binds	PubMed
	HLA-C	downregulates	PubMed
	HLA-C	downregulates	PubMed
	HLA-C	downregulates	PubMed
	HLA-C	downregulates	PubMed
	HLA-C	interacts with	PubMed
	HLA-C	downregulates	PubMed
	HLA-C	downregulates	PubMed
	HLA-C	complexes with	PubMed
	HLA-C	downregulates	PubMed
	HLA-C	downregulates	PubMed
	HLA-C	downregulates	PubMed
	HLA-C	downregulates	PubMed
	HLA-C	downregulates	PubMed
	HLA-C	downregulates	PubMed
	HLA-C	downregulates	PubMed
	HLA-C	interacts with	PubMed
	HLA-C	downregulates	PubMed
	HLA-C	downregulates	PubMed
	HLA-C	degrades	PubMed
	HLA-C	downregulates	PubMed
HLA class II histocompatibility antigen, DM alpha chain precursor	HLA-DMA	downregulates	PubMed
	HLA-DMA	downregulates	PubMed
	HLA-DMA	inhibits	PubMed
	HLA-DMA	downregulates	PubMed
HLA class II histocompatibility antigen, DM beta chain precursor	HLA-DMB	downregulates	PubMed
	HLA-DMB	downregulates	PubMed
	HLA-DMB	inhibits	PubMed
	HLA-DMB	downregulates	PubMed
HLA class II histocompatibility antigen, DO alpha chain precursor	HLA-DOA	downregulates	PubMed
	HLA-DOA	downregulates	PubMed
	HLA-DOA	inhibits	PubMed
	HLA-DOA	downregulates	PubMed
HLA class II histocompatibility antigen, DO beta chain precursor	HLA-DOB	downregulates	PubMed
	HLA-DOB	downregulates	PubMed
	HLA-DOB	inhibits	PubMed
	HLA-DOB	downregulates	PubMed
HLA class II histocompatibility antigen, DP alpha 1 chain precursor	HLA-DPA1	downregulates	PubMed
	HLA-DPA1	downregulates	PubMed
	HLA-DPA1	inhibits	PubMed
	HLA-DPA1	downregulates	PubMed
HLA class II histocompatibility antigen, DP beta 1 chain precursor	HLA-DPB1	downregulates	PubMed
	HLA-DPB1	downregulates	PubMed
	HLA-DPB1	inhibits	PubMed
	HLA-DPB1	downregulates	PubMed
HLA class II histocompatibility antigen, DQ alpha 1 chain precursor	HLA-DQA1	downregulates	PubMed
	HLA-DQA1	downregulates	PubMed
	HLA-DQA1	inhibits	PubMed
	HLA-DQA1	downregulates	PubMed
HLA class II histocompatibility antigen, DQ alpha 2 chain precursor	HLA-DQA2	downregulates	PubMed
	HLA-DQA2	downregulates	PubMed
	HLA-DQA2	inhibits	PubMed
	HLA-DQA2	downregulates	PubMed
HLA class II histocompatibility antigen, DQ beta 1 chain isoform 1 precursor	HLA-DQB1	downregulates	PubMed
	HLA-DQB1	downregulates	PubMed
	HLA-DQB1	inhibits	PubMed
	HLA-DQB1	downregulates	PubMed
HLA class II histocompatibility antigen, DQ beta 2 chain isoform 2 precursor	HLA-DQB2	downregulates	PubMed
	HLA-DQB2	downregulates	PubMed
	HLA-DQB2	inhibits	PubMed
	HLA-DQB2	downregulates	PubMed
HLA class II histocompatibility antigen, DR alpha chain precursor	HLA-DRA	downregulates	PubMed
	HLA-DRA	downregulates	PubMed
	HLA-DRA	inhibits	PubMed
	HLA-DRA	downregulates	PubMed
	HLA-DRA	binds	PubMed
	HLA-DRA	downregulates	PubMed
	HLA-DRA	inhibits	PubMed
	HLA-DRA	downregulates	PubMed
major histocompatibility complex, class II, DR beta 1 precursor	HLA-DRB1	downregulates	PubMed
	HLA-DRB1	inhibits	PubMed
	HLA-DRB1	downregulates	PubMed
	HLA-DRB1	downregulates	PubMed
	HLA-DRB1	binds	PubMed
	HLA-DRB1	interacts with	PubMed
major histocompatibility complex, class II, DR beta 3 precursor	HLA-DRB3	inhibits	PubMed
	HLA-DRB3	binds	PubMed
	HLA-DRB3	downregulates	PubMed
	HLA-DRB3	downregulates	PubMed
major histocompatibility complex, class II, DR beta 4 precursor	HLA-DRB4	inhibits	PubMed
	HLA-DRB4	binds	PubMed
	HLA-DRB4	downregulates	PubMed
	HLA-DRB4	downregulates	PubMed
major histocompatibility complex, class II, DR beta 5 precursor	HLA-DRB5	inhibits	PubMed
	HLA-DRB5	downregulates	PubMed
	HLA-DRB5	downregulates	PubMed
	HLA-DRB5	binds	PubMed
HLA class I histocompatibility antigen, alpha chain E precursor	HLA-E	downregulates	PubMed
	HLA-E	downregulates	PubMed
	HLA-E	downregulates	PubMed
	HLA-E	downregulates	PubMed
	HLA-E	binds	PubMed
	HLA-E	downregulates	PubMed
	HLA-E	downregulates	PubMed
	HLA-E	interacts with	PubMed
	HLA-E	downregulates	PubMed
	HLA-E	degrades	PubMed
	HLA-E	downregulates	PubMed
HLA class I histocompatibility antigen, alpha chain F isoform 2 precursor	HLA-F	downregulates	PubMed
	HLA-F	downregulates	PubMed
	HLA-F	downregulates	PubMed
	HLA-F	downregulates	PubMed
	HLA-F	downregulates	PubMed
	HLA-F	downregulates	PubMed
	HLA-F	downregulates	PubMed
	HLA-F	downregulates	PubMed
	HLA-F	binds	PubMed
	HLA-F	interacts with	PubMed
	HLA-F	degrades	PubMed
HLA class I histocompatibility antigen, alpha chain G isoform 2 precursor	HLA-G	downregulates	PubMed
	HLA-G	downregulates	PubMed
	HLA-G	downregulates	PubMed
	HLA-G	downregulates	PubMed
	HLA-G	downregulates	PubMed
	HLA-G	downregulates	PubMed
	HLA-G	downregulates	PubMed
	HLA-G	binds	PubMed
	HLA-G	interacts with	PubMed
	HLA-G	degrades	PubMed
	HLA-G	downregulates	PubMed
	HLA-G	downregulates	PubMed
helicase-like transcription factor isoform 1	HLTF	upregulates	PubMed
3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform 1	HMGCR	modulates	PubMed
heme oxygenase 1	HMOX1	interacts with	PubMed
heterogeneous nuclear ribonucleoprotein A0	HNRNPA0	complexes with	PubMed
heterogeneous nuclear ribonucleoprotein A1 isoform a	HNRNPA1	complexes with	PubMed
heterogeneous nuclear ribonucleoproteins A2/B1 isoform A2	HNRNPA2B1	complexes with	PubMed
heterogeneous nuclear ribonucleoprotein A3 isoform a	HNRNPA3	complexes with	PubMed
heterogeneous nuclear ribonucleoprotein A/B isoform b	HNRNPAB	complexes with	PubMed
heterogeneous nuclear ribonucleoproteins C1/C2 isoform b	HNRNPC	complexes with	PubMed
heterogeneous nuclear ribonucleoprotein D0 isoform c	HNRNPD	complexes with	PubMed
heterogeneous nuclear ribonucleoprotein F	HNRNPF	complexes with	PubMed
heterogeneous nuclear ribonucleoprotein H isoform a	HNRNPH1	complexes with	PubMed
heterogeneous nuclear ribonucleoprotein H2	HNRNPH2	complexes with	PubMed
heterogeneous nuclear ribonucleoprotein H3 isoform a	HNRNPH3	complexes with	PubMed
heterogeneous nuclear ribonucleoprotein K isoform a	HNRNPK	complexes with	PubMed
	HNRNPK	complexes with	PubMed
	HNRNPK	complexes with	PubMed
	HNRNPK	interacts with	PubMed
heterogeneous nuclear ribonucleoprotein M isoform a	HNRNPM	complexes with	PubMed
heterogeneous nuclear ribonucleoprotein R isoform 2	HNRNPR	complexes with	PubMed
heterogeneous nuclear ribonucleoprotein U isoform b	HNRNPU	complexes with	PubMed
GTPase HRas isoform 1	HRAS	activates	PubMed
	HRAS	synergizes with	PubMed
peroxisomal multifunctional enzyme type 2 isoform 2	HSD17B4	complexes with	PubMed
heat shock factor protein 1	HSF1	interacts with	PubMed
heat shock protein HSP 90-alpha isoform 2	HSP90AA1	cooperates with	PubMed
endoplasmin precursor	HSP90B1	requires	PubMed
	HSP90B1	cooperates with	PubMed
heat shock 70 kDa protein 1A	HSPA1A	complexes with	PubMed
	HSPA1A	interacts with	PubMed
	HSPA1A	inhibits	PubMed
heat shock 70 kDa protein 1B	HSPA1B	complexes with	PubMed
	HSPA1B	interacts with	PubMed
	HSPA1B	inhibits	PubMed
heat shock 70 kDa protein 1-like	HSPA1L	complexes with	PubMed
heat shock-related 70 kDa protein 2	HSPA2	interacts with	PubMed
heat shock 70 kDa protein 4	HSPA4	interacts with	PubMed
endoplasmic reticulum chaperone BiP precursor	HSPA5	complexes with	PubMed
	HSPA5	interacts with	PubMed
heat shock 70 kDa protein 6	HSPA6	interacts with	PubMed
heat shock cognate 71 kDa protein isoform 1	HSPA8	complexes with	PubMed
	HSPA8	interacts with	PubMed
	HSPA8	co-localizes with	PubMed
stress-70 protein, mitochondrial precursor	HSPA9	binds	PubMed
	HSPA9	interacts with	PubMed
	HSPA9	complexes with	PubMed
	HSPA9	interacts with	PubMed
60 kDa heat shock protein, mitochondrial	HSPD1	interacts with	PubMed
	HSPD1	complexes with	PubMed
17S U2 SnRNP complex component HTATSF1	HTATSF1	upregulates	PubMed
isoleucine--tRNA ligase, cytoplasmic isoform 1	IARS1	complexes with	PubMed
intercellular adhesion molecule 1 precursor	ICAM1	stimulates	PubMed
	ICAM1	induces release of	PubMed
	ICAM1	co-localizes with	PubMed
	ICAM1	upregulates	PubMed
	ICAM1	interacts with	PubMed
intercellular adhesion molecule 2 precursor	ICAM2	downregulates	PubMed
isocitrate dehydrogenase	IDH3A	complexes with	PubMed
	IDH3G	requires	PubMed
gamma-interferon-inducible protein 16 isoform 1	IFI16	antagonizes	PubMed
interferon-induced transmembrane protein 1	IFITM1	downregulated by	PubMed
interferon-induced transmembrane protein 2	IFITM2	downregulated by	PubMed
interferon-induced transmembrane protein 3	IFITM3	downregulated by	PubMed
	IFITM3	downregulated by	PubMed
interferon alpha-1/13 precursor	IFNA1	disrupts	PubMed
	IFNA1	induces release of	PubMed
	IFNA1	induces release of	PubMed
interferon alpha-10 precursor	IFNA10	induces release of	PubMed
	IFNA10	induces release of	PubMed
	IFNA13	induces release of	PubMed
	IFNA13	induces release of	PubMed
interferon alpha-14 precursor	IFNA14	induces release of	PubMed
	IFNA14	induces release of	PubMed
interferon alpha-16 precursor	IFNA16	induces release of	PubMed
	IFNA16	induces release of	PubMed
interferon alpha-17 precursor	IFNA17	induces release of	PubMed
	IFNA17	induces release of	PubMed
interferon alpha-2 precursor	IFNA2	induces release of	PubMed
	IFNA2	induces release of	PubMed
interferon alpha-21 precursor	IFNA21	induces release of	PubMed
	IFNA21	induces release of	PubMed
interferon alpha-4 precursor	IFNA4	induces release of	PubMed
	IFNA4	induces release of	PubMed
interferon alpha-5 precursor	IFNA5	induces release of	PubMed
	IFNA5	induces release of	PubMed
interferon alpha-6 precursor	IFNA6	induces release of	PubMed
	IFNA6	induces release of	PubMed
interferon alpha-7 precursor	IFNA7	induces release of	PubMed
	IFNA7	induces release of	PubMed
interferon alpha-8 precursor	IFNA8	induces release of	PubMed
	IFNA8	induces release of	PubMed
interferon beta precursor	IFNB1	upregulates	PubMed
	IFNB1	upregulates	PubMed
interferon gamma precursor	IFNG	upregulates	PubMed
	IFNG	interacts with	PubMed
	IFNG	interacts with	PubMed
	IFNG	inhibits	PubMed
	IFNG	inhibits	PubMed
	IFNG	upregulates	PubMed
	IFNG	downregulates	PubMed
	IFNG	upregulates	PubMed
interferon gamma receptor 1 isoform 1 precursor	IFNGR1	downregulates	PubMed
insulin-like growth factor 2 mRNA-binding protein 1 isoform 1	IGF2BP1	complexes with	PubMed
insulin-like growth factor 2 mRNA-binding protein 3	IGF2BP3	complexes with	PubMed
cation-independent mannose-6-phosphate receptor precursor	IGF2R	sequesters	PubMed
inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1	IKBKB	induces phosphorylation of	PubMed
	IKBKB	enhances	PubMed
	IKBKB	activates	PubMed
	IKBKB	induces phosphorylation of	PubMed
	IKBKB	induces phosphorylation of	PubMed
interleukin-10 isoform 1 precursor	IL10	induces release of	PubMed
	IL10	upregulates	PubMed
	IL10	inhibited by	PubMed
	IL10	downregulates	PubMed
	IL10	inhibits	PubMed
	IL10	upregulates	PubMed
	IL10	upregulates	PubMed
interleukin-12 subunit alpha isoform 1 precursor	IL12A	interacts with	PubMed
	IL12A	interacts with	PubMed
	IL12A	upregulates	PubMed
interleukin-12 subunit beta precursor	IL12B	incorporates	PubMed
	IL12B	interacts with	PubMed
	IL12B	upregulates	PubMed
	IL12B	interacts with	PubMed
interleukin-15 isoform 1 preproprotein	IL15	interacts with	PubMed
	IL15	upregulates	PubMed
interleukin-18 isoform 1 precursor	IL18	downregulates	PubMed
interleukin-1 beta proprotein	IL1B	upregulates	PubMed
	IL1B	interacts with	PubMed
	IL1B	upregulates	PubMed
	IL1B	upregulates	PubMed
interleukin-2 precursor	IL2	upregulates	PubMed
	IL2	upregulates	PubMed
	IL2	induces release of	PubMed
	IL2	upregulates	PubMed
	IL2	upregulates	PubMed
	IL2	inhibits	PubMed
	IL2	upregulates	PubMed
	IL2	inhibits	PubMed
	IL2	interacts with	PubMed
	IL2	downregulates	PubMed
	IL2	inhibits	PubMed
interleukin-21 isoform 1 precursor	IL21	upregulates	PubMed
interleukin-2 receptor subunit alpha isoform 1 precursor	IL2RA	enhances	PubMed
	IL2RA	downregulates	PubMed
	IL2RA	upregulates	PubMed
interleukin-32 isoform B	IL32	inhibited by	PubMed
interleukin-4 isoform 1 precursor	IL4	inhibits	PubMed
interleukin-6 isoform 1 precursor	IL6	induces	PubMed
	IL6	induces	PubMed
	IL6	induces	PubMed
	IL6	induces release of	PubMed
	IL6	upregulates	PubMed
	IL6	induces release of	PubMed
	IL6	induces release of	PubMed
	IL6	synergizes with	PubMed
	IL6	synergizes with	PubMed
	IL6	synergizes with	PubMed
	IL6	upregulates	PubMed
	IL6	upregulates	PubMed
	IL6	upregulates	PubMed
	IL6	upregulates	PubMed
	IL6	upregulates	PubMed
interleukin-6 receptor subunit beta isoform 1 precursor	IL6ST	downregulates	PubMed
interleukin enhancer-binding factor 2 isoform 1	ILF2	complexes with	PubMed
interleukin enhancer-binding factor 3 isoform b	ILF3	complexes with	PubMed
alpha-internexin	INA	complexes with	PubMed
importin-7	IPO7	complexes with	PubMed
	IPO7	interacts with	PubMed
ras GTPase-activating-like protein IQGAP1	IQGAP1	complexes with	PubMed
interferon regulatory factor 1 isoform 1	IRF1	upregulates	PubMed
interferon regulatory factor 2	IRF2	upregulates	PubMed
interferon regulatory factor 3 isoform 1	IRF3	activates	PubMed
	IRF3	activates	PubMed
immunity-related GTPase family M protein isoform 2	IRGM	interacts with	PubMed
	IRGM	interacts with	PubMed
E3 ubiquitin-protein ligase Itchy homolog isoform 2	ITCH	co-localizes with	PubMed
	ITCH	mediated by	PubMed
	ITCH	enhances	PubMed
	ITCH	mediated by	PubMed
	ITCH	co-localizes with	PubMed
integrin alpha-L isoform a precursor	ITGAL	downregulates	PubMed
	ITGAL	interacts with	PubMed
integrin alpha-M isoform 2 precursor	ITGAM	interacts with	PubMed
integrin alpha-X isoform 2 precursor	ITGAX	inhibits	PubMed
	ITGAX	downregulates	PubMed
integrin beta-1 isoform 1A precursor	ITGB1	interacts with	PubMed
tyrosine-protein kinase ITK/TSK	ITK	interacts with	PubMed
	ITK	interacts with	PubMed
inositol 1,4,5-trisphosphate receptor type 1 isoform 2	ITPR1	interacts with	PubMed
intersectin-1 isoform ITSN-l	ITSN1	requires	PubMed
transcription factor Jun	JUN	increases phosphorylation of	PubMed
	JUN	enhanced by	PubMed
	JUN	interacts with	PubMed
	JUN	activates	PubMed
	JUN	downregulates	PubMed
BTB/POZ domain-containing protein KCTD19	KCTD19	affected by	PubMed
vascular endothelial growth factor receptor 2 precursor	KDR	upregulates	PubMed
KH domain-containing, RNA-binding, signal transduction-associated protein 1 isoform 1	KHDRBS1	inhibited by	PubMed
far upstream element-binding protein 2 isoform 1	KHSRP	complexes with	PubMed
killer cell immunoglobulin-like receptor 2DL2 precursor	KIR2DL2	inhibits	PubMed
mast/stem cell growth factor receptor Kit isoform 1 precursor	KIT	upregulates	PubMed
NKG2-D type II integral membrane protein	KLRK1	downregulates	PubMed
importin subunit beta-1 isoform 1	KPNB1	complexes with	PubMed
KRR1 small subunit processome component homolog	KRR1	complexes with	PubMed
leukocyte-associated immunoglobulin-like receptor 1 isoform a precursor	LAIR1	downregulates	PubMed
lysosome-associated membrane glycoprotein 1 precursor	LAMP1	co-localizes with	PubMed
	LAMP1	downregulates	PubMed
	LAMP1	interacts with	PubMed
	LAMP1	co-localizes with	PubMed
lysosome-associated membrane glycoprotein 2 isoform A precursor	LAMP2	downregulates	PubMed
	LAMP2	co-localizes with	PubMed
leucine--tRNA ligase, cytoplasmic isoform 1	LARS1	complexes with	PubMed
linker for activation of T-cells family member 1 isoform a	LAT	inhibits	PubMed
	LAT	induces accumulation of	PubMed
tyrosine-protein kinase Lck isoform a	LCK	recruits	PubMed
	LCK	relocalizes	PubMed
	LCK	relocalizes	PubMed
	LCK	upregulates	PubMed
	LCK	interacts with	PubMed
	LCK	complexes with	PubMed
	LCK	inactivates	PubMed
	LCK	binds	PubMed
	LCK	relocalizes	PubMed
	LCK	inhibits	PubMed
	LCK	relocalizes	PubMed
	LCK	induces accumulation of	PubMed
	LCK	interacts with	PubMed
	LCK	activates	PubMed
	LCK	complexes with	PubMed
	LCK	complexes with	PubMed
	LCK	activates	PubMed
	LCK	modulated by	PubMed
	LCK	co-localizes with	PubMed
	LCK	interacts with	PubMed
	LCK	binds	PubMed
	LCK	interacts with	PubMed
	LCK	binds	PubMed
	LCK	requires	PubMed
lymphocyte cytosolic protein 2	LCP2	associates with	PubMed
	LCP2	inhibits	PubMed
	LCP2	inhibits	PubMed
L-lactate dehydrogenase A chain isoform 1	LDHA	complexes with	PubMed
L-lactate dehydrogenase B chain isoform LDHB	LDHB	complexes with	PubMed
low-density lipoprotein receptor isoform 1 precursor	LDLR	upregulates	PubMed
LIM domain kinase 1 isoform 1	LIMK1	activates	PubMed
leucine-rich PPR motif-containing protein, mitochondrial precursor	LRPPRC	complexes with	PubMed
leucine-rich repeat-containing protein 59	LRRC59	complexes with	PubMed
putative RNA-binding protein Luc7-like 2 isoform 1	LUC7L2	complexes with	PubMed
tyrosine-protein kinase Lyn isoform A	LYN	activates	PubMed
	LYN	activates	PubMed
	LYN	interacts with	PubMed
lysosomal-trafficking regulator	LYST	regulated by	PubMed
lysozyme C precursor	LYZ	complexes with	PubMed
myelin and lymphocyte protein isoform a	MAL	interacts with	PubMed
MAL-like protein isoform 1	MALL	requires	PubMed
microtubule-associated proteins 1A/1B light chain 3A isoform a	MAP1LC3A	downregulates	PubMed
microtubule-associated proteins 1A/1B light chain 3B	MAP1LC3B	downregulates	PubMed
microtubule-associated proteins 1A/1B light chain 3C	MAP1LC3C	downregulates	PubMed
dual specificity mitogen-activated protein kinase kinase 1 isoform 1	MAP2K1	induces phosphorylation of	PubMed
	MAP2K1	activates	PubMed
	MAP2K1	upregulates	PubMed
dual specificity mitogen-activated protein kinase kinase 2	MAP2K2	upregulates	PubMed
mitogen-activated protein kinase kinase kinase 5	MAP3K5	inhibits	PubMed
	MAP3K5	interacts with	PubMed
	MAP3K5	binds	PubMed
	MAP3K5	inhibits	PubMed
	MAP3K5	inhibits	PubMed
	MAP3K5	inhibits	PubMed
	MAP3K5	binds	PubMed
mitogen-activated protein kinase kinase kinase 7 isoform A	MAP3K7	activates	PubMed
	MAP3K7	interacts with	PubMed
	MAP3K7	induces phosphorylation of	PubMed
mitogen-activated protein kinase 1	MAPK1	activates	PubMed
	MAPK1	induces phosphorylation of	PubMed
	MAPK1	inhibits	PubMed
	MAPK1	activates	PubMed
	MAPK1	activates	PubMed
	MAPK1	induces phosphorylation of	PubMed
	MAPK1	activates	PubMed
	MAPK1	activates	PubMed
	MAPK1	induces phosphorylation of	PubMed
	MAPK1	activates	PubMed
	MAPK1	binds	PubMed
	MAPK1	activates	PubMed
	MAPK1	activates	PubMed
	MAPK1	activates	PubMed
	MAPK1	regulated by	PubMed
	MAPK1	upregulates	PubMed
	MAPK1	activates	PubMed
	MAPK1	activates	PubMed
	MAPK1	inhibits	PubMed
mitogen-activated protein kinase 11	MAPK11	involves	PubMed
mitogen-activated protein kinase 13	MAPK13	involves	PubMed
	MAPK13	interacts with	PubMed
mitogen-activated protein kinase 14 isoform 1	MAPK14	activates	PubMed
	MAPK14	induces phosphorylation of	PubMed
	MAPK14	interacts with	PubMed
	MAPK14	regulated by	PubMed
	MAPK14	inhibits	PubMed
	MAPK14	activates	PubMed
mitogen-activated protein kinase 3 isoform 1	MAPK3	activates	PubMed
	MAPK3	induces phosphorylation of	PubMed
	MAPK3	activates	PubMed
	MAPK3	induces phosphorylation of	PubMed
	MAPK3	activates	PubMed
	MAPK3	induces phosphorylation of	PubMed
	MAPK3	activates	PubMed
	MAPK3	activates	PubMed
mitogen-activated protein kinase 8 isoform alpha2	MAPK8	activates	PubMed
	MAPK8	inhibits	PubMed
	MAPK8	activates	PubMed
	MAPK8	activates	PubMed
	MAPK8	activates	PubMed
matrin-3 isoform a	MATR3	complexes with	PubMed
mitochondrial antiviral-signaling protein isoform 2	MAVS	degrades	PubMed
	MAVS	blocks	PubMed
DNA replication licensing factor MCM7 isoform 1	MCM7	complexes with	PubMed
methyl-CpG-binding protein 2 isoform 1	MECP2	interacts with	PubMed
microfibrillar-associated protein 2 isoform a precursor	MFAP2	binds	PubMed
MHC class I polypeptide-related sequence A isoform 1 (MICA*001) precursor	MICA	downregulates	PubMed
	MICA	downregulates	PubMed
macrophage migration inhibitory factor	MIF	incorporates	PubMed
migration and invasion-inhibitory protein	MIIP	affected by	PubMed
proliferation marker protein Ki-67 isoform 1	MKI67	upregulates	PubMed
72 kDa type IV collagenase isoform 1 preproprotein	MMP2	activates	PubMed
matrix metalloproteinase-9 preproprotein	MMP9	activates	PubMed
	MMP9	activates	PubMed
mannosyl-oligosaccharide glucosidase isoform 1	MOGS	complexes with	PubMed
helicase MOV-10 isoform 1	MOV10	complexes with	PubMed
macrophage mannose receptor 1 precursor	MRC1	downregulates	PubMed
mitochondrial carrier homolog 1 isoform PSAP-LS	MTCH1	interacts with	PubMed
bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform A precursor	MTHFD2	interacts with	PubMed
serine/threonine-protein kinase mTOR isoform 1	MTOR	activates	PubMed
mucin-1 isoform 1 precursor	MUC1	downregulates	PubMed
myb-binding protein 1A isoform 2	MYBBP1A	complexes with	PubMed
myosin-9	MYH9	downregulates	PubMed
SH2/SH3 adapter protein NCK1 isoform 1	NCK1	associates with	PubMed
nucleolin	NCL	complexes with	PubMed
E3 ubiquitin-protein ligase NEDD4 isoform 1	NEDD4	co-localizes with	PubMed
	NEDD4	co-localizes with	PubMed
merlin isoform 1	NF2	induces phosphorylation of	PubMed
nuclear factor of activated T-cells 5 isoform c	NFAT5	regulates	PubMed
nuclear factor of activated T-cells, cytoplasmic 1 isoform B	NFATC1	regulates	PubMed
	NFATC1	upregulates	PubMed
	NFATC1	activates	PubMed
	NFATC1	inhibits	PubMed
nuclear factor of activated T-cells, cytoplasmic 2 isoform B	NFATC2	regulates	PubMed
	NFATC2	inhibits	PubMed
	NFATC2	activates	PubMed
nuclear factor of activated T-cells, cytoplasmic 3 isoform 2	NFATC3	regulates	PubMed
nuclear factor of activated T-cells, cytoplasmic 4 isoform 2	NFATC4	regulates	PubMed
nuclear factor NF-kappa-B p105 subunit isoform 1	NFKB1	modulates	PubMed
	NFKB1	enhances	PubMed
	NFKB1	activates	PubMed
	NFKB1	activates	PubMed
	NFKB1	interacts with	PubMed
	NFKB1	downregulates	PubMed
	NFKB1	activates	PubMed
	NFKB1	activates	PubMed
	NFKB1	activates	PubMed
	NFKB1	binds	PubMed
	NFKB1	activates	PubMed
	NFKB1	inhibits	PubMed
	NFKB1	inhibits	PubMed
	NFKB1	inhibits	PubMed
	NFKB1	inhibits	PubMed
NF-kappa-B inhibitor alpha	NFKBIA	activates	PubMed
	NFKBIA	induces phosphorylation of	PubMed
	NFKBIA	degrades	PubMed
	NFKBIA	upregulates	PubMed
	NFKBIA	degrades	PubMed
NF-kappa-B-repressing factor isoform 2	NKRF	complexes with	PubMed
nucleoside diphosphate kinase 6 isoform 1	NME6	requires	PubMed
glycylpeptide N-tetradecanoyltransferase 1	NMT1	interacts with	PubMed
	NMT1	myristoylated by	PubMed
	NMT1	interacts with	PubMed
glycylpeptide N-tetradecanoyltransferase 2 isoform 1	NMT2	myristoylated by	PubMed
non-POU domain-containing octamer-binding protein isoform 1	NONO	complexes with	PubMed
nitric oxide synthase 3 isoform 1	NOS3	downregulates	PubMed
NADPH oxidase 1 isoform 1	NOX1	requires	PubMed
	NOX1	inhibits	PubMed
	NOX1	phosphorylates	PubMed
	NOX1	activates	PubMed
NADPH oxidase 3	NOX3	requires	PubMed
NADPH oxidase 4 isoform a	NOX4	requires	PubMed
nucleophosmin isoform 1	NPM1	complexes with	PubMed
GTPase NRas	NRAS	activates	PubMed
neuropilin-1 isoform a precursor	NRP1	upregulates	PubMed
vesicle-fusing ATPase	NSF	complexes with	PubMed
cleavage and polyadenylation specificity factor subunit 5	NUDT21	complexes with	PubMed
nuclear pore complex protein Nup155 isoform 2	NUP155	complexes with	PubMed
2'-5'-oligoadenylate synthase 1 isoform 3	OAS1	antagonizes	PubMed
ornithine aminotransferase, mitochondrial isoform 1 precursor	OAT	complexes with	PubMed
OCIA domain-containing protein 1 isoform 1	OCIAD1	interacts with	PubMed
occludin isoform a	OCLN	downregulates	PubMed
oncostatin-M isoform 1 preproprotein	OSM	incorporates	PubMed
ubiquitin thioesterase OTUB1	OTUB1	downregulates	PubMed
transmembrane prolyl 4-hydroxylase isoform a	P4HTM	interacts with	PubMed
polyadenylate-binding protein 1	PABPC1	complexes with	PubMed
polyadenylate-binding protein 4 isoform 2	PABPC4	complexes with	PubMed
polyadenylate-binding protein 2 isoform 1	PABPN1	complexes with	PubMed
phosphofurin acidic cluster sorting protein 1	PACS1	interacts with	PubMed
	PACS1	binds	PubMed
	PACS1	binds	PubMed
	PACS1	binds	PubMed
	PACS1	interacts with	PubMed
phosphofurin acidic cluster sorting protein 2 isoform 2	PACS2	binds	PubMed
	PACS2	binds	PubMed
serine/threonine-protein kinase PAK 1 isoform 2	PAK1	inhibits	PubMed
	PAK1	interacts with	PubMed
	PAK1	interacts with	PubMed
	PAK1	activates	PubMed
	PAK1	activates	PubMed
	PAK1	activates	PubMed
	PAK1	activates	PubMed
	PAK1	activates	PubMed
	PAK1	associates with	PubMed
	PAK1	associates with	PubMed
serine/threonine-protein kinase PAK 2	PAK2	requires	PubMed
	PAK2	requires	PubMed
	PAK2	activates	PubMed
	PAK2	activates	PubMed
	PAK2	associates with	PubMed
	PAK2	associates with	PubMed
	PAK2	activates	PubMed
	PAK2	induces phosphorylation of	PubMed
	PAK2	interacts with	PubMed
	PAK2	associates with	PubMed
	PAK2	complexes with	PubMed
	PAK2	associates with	PubMed
	PAK2	associates with	PubMed
	PAK2	associates with	PubMed
	PAK2	associates with	PubMed
	PAK2	activates	PubMed
	PAK2	regulates	PubMed
	PAK2	interacts with	PubMed
	PAK2	binds	PubMed
	PAK2	binds	PubMed
	PAK2	co-localizes with	PubMed
poly	PARP1	induces cleavage of	PubMed
	PARP1	induces cleavage of	PubMed
poly(rC)-binding protein 1	PCBP1	complexes with	PubMed
protein piccolo isoform 2	PCLO	requires	PubMed
programmed cell death protein 1 precursor	PDCD1	upregulates	PubMed
programmed cell death 6-interacting protein isoform 1	PDCD6IP	interacts with	PubMed
	PDCD6IP	interacts with	PubMed
	PDCD6IP	binds	PubMed
	PDCD6IP	co-localizes with	PubMed
pyruvate dehydrogenase E1 component subunit beta, mitochondrial isoform 1 precursor	PDHB	complexes with	PubMed
phosphatidylethanolamine-binding protein 1	PEBP1	interacts with	PubMed
prohibitin 1 isoform 1	PHB1	complexes with	PubMed
prohibitin-2 isoform 1	PHB2	complexes with	PubMed
phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform 1	PIK3C2A	interacts with	PubMed
	PIK3C2A	complexes with	PubMed
	PIK3C2A	upregulates	PubMed
	PIK3C2A	downregulates	PubMed
phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform 1	PIK3C2B	interacts with	PubMed
	PIK3C2B	complexes with	PubMed
	PIK3C2B	upregulates	PubMed
	PIK3C2B	downregulates	PubMed
phosphatidylinositol 3-kinase C2 domain-containing subunit gamma isoform 3	PIK3C2G	interacts with	PubMed
	PIK3C2G	complexes with	PubMed
	PIK3C2G	upregulates	PubMed
	PIK3C2G	downregulates	PubMed
phosphatidylinositol 3-kinase catalytic subunit type 3 isoform 1	PIK3C3	interacts with	PubMed
	PIK3C3	complexes with	PubMed
	PIK3C3	upregulates	PubMed
	PIK3C3	downregulates	PubMed
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	PIK3CA	interacts with	PubMed
	PIK3CA	mediated by	PubMed
	PIK3CA	involves	PubMed
	PIK3CA	activates	PubMed
	PIK3CA	complexes with	PubMed
	PIK3CA	upregulates	PubMed
	PIK3CA	interacts with	PubMed
	PIK3CA	downregulates	PubMed
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform 1	PIK3CB	interacts with	PubMed
	PIK3CB	mediated by	PubMed
	PIK3CB	involves	PubMed
	PIK3CB	activates	PubMed
	PIK3CB	interacts with	PubMed
	PIK3CB	complexes with	PubMed
	PIK3CB	upregulates	PubMed
	PIK3CB	downregulates	PubMed
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform 1	PIK3CD	involves	PubMed
	PIK3CD	activates	PubMed
	PIK3CD	interacts with	PubMed
	PIK3CD	complexes with	PubMed
	PIK3CD	upregulates	PubMed
	PIK3CD	downregulates	PubMed
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	PIK3CG	interacts with	PubMed
	PIK3CG	mediated by	PubMed
	PIK3CG	involves	PubMed
	PIK3CG	activates	PubMed
	PIK3CG	interacts with	PubMed
	PIK3CG	downregulates	PubMed
	PIK3CG	complexes with	PubMed
	PIK3CG	upregulates	PubMed
phosphatidylinositol 3-kinase regulatory subunit alpha isoform 1	PIK3R1	activates	PubMed
	PIK3R1	associates with	PubMed
	PIK3R1	complexes with	PubMed
	PIK3R1	upregulates	PubMed
	PIK3R1	interacts with	PubMed
	PIK3R1	downregulates	PubMed
	PIK3R1	binds	PubMed
phosphatidylinositol 3-kinase regulatory subunit beta	PIK3R2	activates	PubMed
	PIK3R2	associates with	PubMed
	PIK3R2	interacts with	PubMed
	PIK3R2	complexes with	PubMed
	PIK3R2	upregulates	PubMed
	PIK3R2	downregulates	PubMed
pyruvate kinase PKM isoform a	PKM	complexes with	PubMed
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform a	PLCG1	inhibits	PubMed
plastin-3 isoform 1	PLS3	complexes with	PubMed
protein TMEPAI isoform a	PMEPA1	interacts with	PubMed
peroxisome proliferator-activated receptor gamma isoform 1	PPARG	downregulates	PubMed
platelet basic protein preproprotein	PPBP	incorporates	PubMed
peptidyl-prolyl cis-trans isomerase A isoform 1	PPIA	downregulates	PubMed
	PPIA	binds	PubMed
peroxiredoxin-6	PRDX6	complexes with	PubMed
perforin-1 precursor	PRF1	upregulates	PubMed
cAMP-dependent protein kinase catalytic subunit alpha isoform Calpha1	PRKACA	phosphorylated by	PubMed
cAMP-dependent protein kinase catalytic subunit beta isoform 2	PRKACB	phosphorylated by	PubMed
cAMP-dependent protein kinase catalytic subunit gamma	PRKACG	phosphorylated by	PubMed
cAMP-dependent protein kinase type I-alpha regulatory subunit isoform a	PRKAR1A	phosphorylated by	PubMed
cAMP-dependent protein kinase type I-beta regulatory subunit	PRKAR1B	phosphorylated by	PubMed
cAMP-dependent protein kinase type II-alpha regulatory subunit isoform a	PRKAR2A	phosphorylated by	PubMed
cAMP-dependent protein kinase type II-beta regulatory subunit	PRKAR2B	phosphorylated by	PubMed
protein kinase C alpha type	PRKCA	requires	PubMed
	PRKCA	phosphorylated by	PubMed
	PRKCA	phosphorylated by	PubMed
protein kinase C beta type isoform 2	PRKCB	downregulates	PubMed
protein kinase C delta type isoform c	PRKCD	complexes with	PubMed
	PRKCD	complexes with	PubMed
	PRKCD	complexes with	PubMed
protein kinase C epsilon type	PRKCE	involves	PubMed
	PRKCE	downregulates	PubMed
protein kinase C eta type	PRKCH	associates with	PubMed
protein kinase C theta type isoform 1	PRKCQ	complexes with	PubMed
	PRKCQ	complexes with	PubMed
	PRKCQ	interacts with	PubMed
DNA-dependent protein kinase catalytic subunit isoform 1	PRKDC	complexes with	PubMed
pre-mRNA-processing factor 40 homolog A isoform 1	PRPF40A	complexes with	PubMed
pre-mRNA-processing-splicing factor 8	PRPF8	complexes with	PubMed
proteasome subunit beta type-4	PSMB4	downregulates	PubMed
	PSMB4	binds	PubMed
26S proteasome regulatory subunit 10B	PSMC6	complexes with	PubMed
26S proteasome non-ATPase regulatory subunit 2 isoform 1	PSMD2	complexes with	PubMed
small ribosomal subunit protein mS39 precursor	PTCD3	complexes with	PubMed
phosphatidylserine synthase 1 isoform 1	PTDSS1	complexes with	PubMed
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform PTEN	PTEN	interacts with	PubMed
prostaglandin G/H synthase 2 precursor	PTGS2	downregulates	PubMed
protein-tyrosine kinase 2-beta isoform a	PTK2B	upregulates	PubMed
receptor-type tyrosine-protein phosphatase C isoform 1 precursor	PTPRC	upregulates	PubMed
poliovirus receptor isoform alpha precursor	PVR	downregulates	PubMed
	PVR	downregulates	PubMed
	PVR	downregulates	PubMed
	PVR	relocalizes	PubMed
	PVR	interacts with	PubMed
paxillin isoform 1	PXN	induces phosphorylation of	PubMed
	PXN	induces phosphorylation of	PubMed
glycogen phosphorylase, liver form isoform 1	PYGL	complexes with	PubMed
ras-related protein Rab-10	RAB10	complexes with	PubMed
ras-related protein Rab-11A isoform 1	RAB11A	co-localizes with	PubMed
	RAB11A	inhibited by	PubMed
ras-related protein Rab-11B	RAB11B	inhibited by	PubMed
	RAB11B	co-localizes with	PubMed
ras-related protein Rab-40A	RAB40A	requires	PubMed
ras-related protein Rab-5A isoform 1	RAB5A	localizes with	PubMed
	RAB5A	interacts with	PubMed
	RAB5A	requires	PubMed
	RAB5A	regulated by	PubMed
ras-related protein Rab-5C isoform a	RAB5C	complexes with	PubMed
ras-related protein Rab-7a	RAB7A	requires	PubMed
	RAB7A	interacts with	PubMed
ras-related protein Rab-8A	RAB8A	complexes with	PubMed
ras-related protein Rab-9A	RAB9A	disrupts	PubMed
rab GTPase-binding effector protein 1 isoform 1	RABEP1	requires	PubMed
ras-related C3 botulinum toxin substrate 1 isoform Rac1	RAC1	interacts with	PubMed
	RAC1	enhances	PubMed
	RAC1	inhibited by	PubMed
	RAC1	interacts with	PubMed
	RAC1	activates	PubMed
ras-related C3 botulinum toxin substrate 2	RAC2	interacts with	PubMed
small ribosomal subunit protein RACK1	RACK1	complexes with	PubMed
	RACK1	binds	PubMed
UL-16 binding protein 5 preproprotein	RAET1G	downregulates	PubMed
UL16-binding protein 6 precursor	RAET1L	downregulates	PubMed
RAF proto-oncogene serine/threonine-protein kinase isoform b	RAF1	binds	PubMed
GTP-binding nuclear protein Ran isoform 1	RAN	complexes with	PubMed
retinoic acid receptor alpha isoform 1	RARA	inhibits	PubMed
retinoic acid receptor beta isoform 1	RARB	inhibits	PubMed
retinoic acid receptor gamma isoform 1	RARG	inhibits	PubMed
ras association domain-containing protein 9	RASSF9	requires	PubMed
ribonucleoprotein PTB-binding 1	RAVER1	complexes with	PubMed
retinoblastoma-associated protein isoform 1	RB1	upregulates	PubMed
RNA-binding motif protein, X chromosome isoform 1	RBMX	complexes with	PubMed
transcription factor p65 isoform 1	RELA	induces	PubMed
	RELA	enhances	PubMed
	RELA	interacts with	PubMed
transforming protein RhoA isoform 1 precursor	RHOA	downregulates	PubMed
rho-related GTP-binding protein RhoF	RHOF	enhances	PubMed
E3 ubiquitin-protein ligase BRE1A	RNF20	complexes with	PubMed
large ribosomal subunit protein uL16 isoform a	RPL10	complexes with	PubMed
large ribosomal subunit protein eL13 isoform 1	RPL13	complexes with	PubMed
large ribosomal subunit protein eL14	RPL14	complexes with	PubMed
large ribosomal subunit protein uL22 isoform a	RPL17	complexes with	PubMed
large ribosomal subunit protein eL18 isoform 1	RPL18	complexes with	PubMed
large ribosomal subunit protein eL19 isoform 1	RPL19	complexes with	PubMed
large ribosomal subunit protein eL24	RPL24	complexes with	PubMed
large ribosomal subunit protein eL29	RPL29	complexes with	PubMed
large ribosomal subunit protein uL3 isoform a	RPL3	complexes with	PubMed
large ribosomal subunit protein uL4	RPL4	complexes with	PubMed
large ribosomal subunit protein uL18	RPL5	complexes with	PubMed
large ribosomal subunit protein eL6 isoform 1	RPL6	complexes with	PubMed
large ribosomal subunit protein uL30 isoform 1	RPL7	complexes with	PubMed
large ribosomal subunit protein eL8	RPL7A	complexes with	PubMed
large ribosomal subunit protein uL2	RPL8	complexes with	PubMed
large ribosomal subunit protein uL6	RPL9	complexes with	PubMed
large ribosomal subunit protein uL10	RPLP0	complexes with	PubMed
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 precursor	RPN1	complexes with	PubMed
small ribosomal subunit protein eS10	RPS10	interacts with	PubMed
small ribosomal subunit protein uS5	RPS2	complexes with	PubMed
small ribosomal subunit protein uS10 isoform 2	RPS20	binds	PubMed
small ribosomal subunit protein uS3 isoform 1	RPS3	complexes with	PubMed
small ribosomal subunit protein eS4, X isoform	RPS4X	complexes with	PubMed
small ribosomal subunit protein eS6	RPS6	complexes with	PubMed
small ribosomal subunit protein eS8	RPS8	complexes with	PubMed
small ribosomal subunit protein uS4 isoform a	RPS9	complexes with	PubMed
ras-related GTP-binding protein A	RRAGA	complexes with	PubMed
runt-related transcription factor 2 isoform b	RUNX2	downregulates	PubMed
retinoic acid receptor RXR-alpha isoform a	RXRA	inhibits	PubMed
retinoic acid receptor RXR-beta isoform 2	RXRB	inhibits	PubMed
retinoic acid receptor RXR-gamma isoform a	RXRG	inhibits	PubMed
scaffold attachment factor B1 isoform 3	SAFB	complexes with	PubMed
U4/U6.U5 tri-snRNP-associated protein 1	SART1	complexes with	PubMed
SCY1-like protein 2 isoform 1	SCYL2	requires	PubMed
syndecan-3	SDC3	inhibits	PubMed
syndecan-4 precursor	SDC4	enhances	PubMed
syntenin-1 isoform 1	SDCBP	inhibits	PubMed
syntenin-2 isoform b	SDCBP2	inhibits	PubMed
succinate dehydrogenase	SDHA	interacts with	PubMed
protein transport protein Sec61 subunit alpha isoform 1 isoform 1	SEC61A1	complexes with	PubMed
L-selectin precursor	SELL	downregulates	PubMed
	SELL	downregulates	PubMed
semaphorin-3A precursor	SEMA3A	downregulates	PubMed
semaphorin-4D isoform 1 precursor	SEMA4D	downregulates	PubMed
semaphorin-7A isoform 1 preproprotein	SEMA7A	downregulates	PubMed
serine incorporator 3	SERINC3	counteracts	PubMed
	SERINC3	downregulates	PubMed
	SERINC3	downregulates	PubMed
serine incorporator 5 isoform 3	SERINC5	antagonizes	PubMed
	SERINC5	antagonizes	PubMed
	SERINC5	counteracts	PubMed
	SERINC5	relocalizes	PubMed
	SERINC5	downregulates	PubMed
	SERINC5	antagonizes	PubMed
	SERINC5	downregulates	PubMed
serpin H1 precursor	SERPINH1	complexes with	PubMed
splicing factor 3B subunit 1 isoform 1	SF3B1	complexes with	PubMed
splicing factor 3B subunit 2	SF3B2	complexes with	PubMed
splicing factor 3B subunit 4	SF3B4	complexes with	PubMed
splicing factor, proline- and glutamine-rich	SFPQ	complexes with	PubMed
sideroflexin-1 isoform 1	SFXN1	complexes with	PubMed
SH2B adapter protein 2 isoform 1	SH2B2	requires	PubMed
SH3 domain-binding protein 4	SH3BP4	requires	PubMed
SH3 domain-containing kinase-binding protein 1 isoform a	SH3KBP1	requires	PubMed
SLAM family member 6 isoform 1 precursor	SLAMF6	downregulates	PubMed
mitochondrial 2-oxoglutarate/malate carrier protein isoform 1	SLC25A11	complexes with	PubMed
ADP/ATP translocase 2	SLC25A5	complexes with	PubMed
long-chain fatty acid transport protein 1	SLC27A1	interacts with	PubMed
solute carrier family 2, facilitated glucose transporter member 4	SLC2A4	inhibits	PubMed
sodium-dependent dopamine transporter	SLC6A3	affected by	PubMed
sodium/hydrogen exchanger 1	SLC9A1	imported by	PubMed
sodium/hydrogen exchanger 2 precursor	SLC9A2	imported by	PubMed
sodium/hydrogen exchanger 3 isoform 1 precursor	SLC9A3	imported by	PubMed
sodium/hydrogen exchanger 4 precursor	SLC9A4	imported by	PubMed
sodium/hydrogen exchanger 5 isoform 1 precursor	SLC9A5	imported by	PubMed
sodium/hydrogen exchanger 6 isoform b precursor	SLC9A6	imported by	PubMed
sodium/hydrogen exchanger 7 isoform 2	SLC9A7	imported by	PubMed
sodium/hydrogen exchanger 8 isoform 2	SLC9A8	imported by	PubMed
sodium/hydrogen exchanger 9	SLC9A9	imported by	PubMed
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 isoform a	SMARCB1	interacts with	PubMed
	SMARCB1	binds	PubMed
structural maintenance of chromosomes protein 1A isoform 1	SMC1A	complexes with	PubMed
sphingomyelin phosphodiesterase isoform 1 precursor	SMPD1	inhibits	PubMed
	SMPD1	modulates	PubMed
sphingomyelin phosphodiesterase 2	SMPD2	inhibits	PubMed
sphingomyelin phosphodiesterase 3	SMPD3	inhibits	PubMed
U5 small nuclear ribonucleoprotein 200 kDa helicase	SNRNP200	complexes with	PubMed
U1 small nuclear ribonucleoprotein A	SNRPA	upregulates	PubMed
alpha-1-syntrophin isoform 1	SNTA1	interacts with	PubMed
beta-1-syntrophin	SNTB1	interacts with	PubMed
beta-2-syntrophin	SNTB2	interacts with	PubMed
gamma-2-syntrophin	SNTG2	interacts with	PubMed
sorting nexin-18 isoform b	SNX18	associates with	PubMed
sorting nexin-22	SNX22	requires	PubMed
sorting nexin-29 isoform 1	SNX29	requires	PubMed
sorting nexin-31 isoform 1	SNX31	requires	PubMed
sorting nexin-6 isoform a	SNX6	requires	PubMed
suppressor of cytokine signaling 1	SOCS1	upregulates	PubMed
leukosialin precursor	SPN	antagonizes	PubMed
protein sprouty homolog 2	SPRY2	inhibited by	PubMed
spectrin alpha chain, non-erythrocytic 1 isoform 2	SPTAN1	complexes with	PubMed
sequestosome-1 isoform 1	SQSTM1	upregulates	PubMed
proto-oncogene tyrosine-protein kinase Src	SRC	activates	PubMed
	SRC	binds	PubMed
	SRC	interacts with	PubMed
	SRC	interacts with	PubMed
	SRC	binds	PubMed
sterol regulatory element-binding protein 2	SREBF2	upregulates	PubMed
signal recognition particle subunit SRP68 isoform 1	SRP68	complexes with	PubMed
signal recognition particle subunit SRP72 isoform 1	SRP72	complexes with	PubMed
signal recognition particle receptor subunit beta	SRPRB	complexes with	PubMed
serine/arginine-rich splicing factor 1 isoform 1	SRSF1	complexes with	PubMed
serine/arginine-rich splicing factor 10 isoform 1	SRSF10	complexes with	PubMed
serine/arginine-rich splicing factor 4	SRSF4	complexes with	PubMed
serine/arginine-rich splicing factor 5 isoform 1	SRSF5	regulated by	PubMed
serine/arginine-rich splicing factor 6	SRSF6	inhibited by	PubMed
serine/arginine-rich splicing factor 7 isoform 1	SRSF7	complexes with	PubMed
signal transducer and activator of transcription 1-alpha/beta isoform alpha	STAT1	induces phosphorylation of	PubMed
	STAT1	induces phosphorylation of	PubMed
	STAT1	induces phosphorylation of	PubMed
	STAT1	activates	PubMed
signal transducer and activator of transcription 2 isoform 1	STAT2	induces phosphorylation of	PubMed
signal transducer and activator of transcription 3 isoform 1	STAT3	interacts with	PubMed
	STAT3	induces phosphorylation of	PubMed
	STAT3	induces phosphorylation of	PubMed
	STAT3	interacts with	PubMed
	STAT3	activates	PubMed
	STAT3	activates	PubMed
	STAT3	upregulates	PubMed
	STAT3	activates	PubMed
	STAT3	activates	PubMed
double-stranded RNA-binding protein Staufen homolog 1 isoform a	STAU1	complexes with	PubMed
syntaxin-6 isoform 1	STX6	requires	PubMed
syntaxin-8	STX8	interacts with	PubMed
syntaxin-binding protein 1 isoform a	STXBP1	requires	PubMed
syntaxin-binding protein 4 isoform 1	STXBP4	requires	PubMed
tyrosine-protein kinase SYK isoform Syk(L)	SYK	recruits	PubMed
heterogeneous nuclear ribonucleoprotein Q isoform 1	SYNCRIP	complexes with	PubMed
synaptopodin isoform A	SYNPO	downregulates	PubMed
TAR DNA-binding protein 43	TARDBP	complexes with	PubMed
TBC1 domain family member 4 isoform 1	TBC1D4	decreases phosphorylation of	PubMed
T-complex protein 1 subunit alpha isoform a	TCP1	complexes with	PubMed
tyrosine-protein kinase Tec	TEC	interacts with	PubMed
serotransferrin isoform 1 precursor	TF	co-localizes with	PubMed
transcription factor AP-2-alpha isoform b	TFAP2A	enhanced by	PubMed
transcription factor EB isoform 2	TFEB	inhibits	PubMed
transferrin receptor protein 1 isoform 1	TFRC	downregulates	PubMed
	TFRC	modulates	PubMed
	TFRC	downregulates	PubMed
THO complex subunit 2	THOC2	complexes with	PubMed
tight junction protein ZO-1 isoform a	TJP1	downregulates	PubMed
toll-like receptor 2 precursor	TLR2	upregulates	PubMed
	TLR2	upregulates	PubMed
tumor necrosis factor	TNF	incorporates	PubMed
	TNF	enhances	PubMed
	TNF	upregulates	PubMed
	TNF	upregulates	PubMed
	TNF	induces release of	PubMed
	TNF	interacts with	PubMed
	TNF	inhibits	PubMed
	TNF	induces release of	PubMed
	TNF	induces cleavage of	PubMed
	TNF	upregulates	PubMed
	TNF	upregulates	PubMed
	TNF	upregulates	PubMed
	TNF	inhibits	PubMed
	TNF	activates	PubMed
	TNF	disrupts	PubMed
	TNF	upregulates	PubMed
	TNF	upregulates	PubMed
	TNF	upregulates	PubMed
	TNF	upregulates	PubMed
	TNF	upregulates	PubMed
	TNF	inhibits	PubMed
	TNF	upregulates	PubMed
	TNF	upregulates	PubMed
tumor necrosis factor receptor superfamily member 1A isoform 1 precursor	TNFRSF1A	downregulates	PubMed
tumor necrosis factor receptor superfamily member 1B precursor	TNFRSF1B	downregulates	PubMed
tumor necrosis factor receptor superfamily member 8 isoform 1 precursor	TNFRSF8	downregulates	PubMed
tumor necrosis factor receptor superfamily member 9 precursor	TNFRSF9	upregulates	PubMed
tumor necrosis factor ligand superfamily member 13B isoform 1	TNFSF13B	upregulates	PubMed
tumor necrosis factor ligand superfamily member 14 isoform 1	TNFSF14	upregulates	PubMed
TNFAIP3-interacting protein 1 isoform 3	TNIP1	binds	PubMed
trinucleotide repeat-containing gene 6A protein isoform 1	TNRC6A	inhibits	PubMed
cellular tumor antigen p53 isoform a	TP53	interacts with	PubMed
	TP53	binds	PubMed
TNF receptor-associated factor 2	TRAF2	interacts with	PubMed
	TRAF2	interacts with	PubMed
	TRAF2	binds	PubMed
	TRAF2	requires	PubMed
TNF receptor-associated factor 5 isoform b	TRAF5	interacts with	PubMed
	TRAF5	interacts with	PubMed
TNF receptor-associated factor 6	TRAF6	interacts with	PubMed
	TRAF6	interacts with	PubMed
	TRAF6	requires	PubMed
	TRAF6	binds	PubMed
transcription intermediary factor 1-beta	TRIM28	complexes with	PubMed
tumor susceptibility gene 101 protein	TSG101	enhances release of	PubMed
	TSG101	interacts with	PubMed
	TSG101	associates with	PubMed
tetraspanin-7	TSPAN7	downregulates	PubMed
	TSPAN7	interacts with	PubMed
tubulin alpha-1A chain isoform 1	TUBA1A	complexes with	PubMed
tubulin alpha-4A chain isoform 1	TUBA4A	complexes with	PubMed
thioredoxin isoform 1	TXN	stabilizes	PubMed
ubiquitin-conjugating enzyme E2 L3 isoform 1	UBE2L3	relocalizes	PubMed
	UBE2L3	relocalizes	PubMed
UL16-binding protein 1 isoform 1 precursor	ULBP1	downregulates	PubMed
UL16-binding protein 2 preproprotein	ULBP2	downregulates	PubMed
	ULBP2	downregulates	PubMed
serine/threonine-protein kinase ULK1	ULK1	downregulates	PubMed
protein unc-119 homolog A isoform a	UNC119	regulated by	PubMed
regulator of nonsense transcripts 1 isoform 2	UPF1	complexes with	PubMed
regulator of nonsense transcripts 3B isoform 2	UPF3B	complexes with	PubMed
vesicle-associated membrane protein 3	VAMP3	inhibits	PubMed
proto-oncogene vav isoform 1	VAV1	associates with	PubMed
	VAV1	recruits	PubMed
	VAV1	binds	PubMed
	VAV1	binds	PubMed
guanine nucleotide exchange factor VAV2 isoform 2	VAV2	binds	PubMed
	VAV2	binds	PubMed
vinculin isoform VCL	VCL	co-localizes with	PubMed
	VCL	polarizes	PubMed
voltage-dependent anion-selective channel protein 1 isoform 1	VDAC1	downregulates	PubMed
vascular endothelial growth factor A, long form isoform b	VEGFA	enhances	PubMed
	VEGFA	upregulates	PubMed
vimentin	VIM	complexes with	PubMed
vacuolar protein sorting-associated protein 4A	VPS4A	requires	PubMed
vacuolar protein sorting-associated protein 4B	VPS4B	requires	PubMed
V-set and immunoglobulin domain-containing protein 4 isoform 1 precursor	VSIG4	interacts with	PubMed
actin-binding protein WASF1	WASF1	induces phosphorylation of	PubMed
actin-binding protein WASF2 isoform 1	WASF2	induces phosphorylation of	PubMed
actin-binding protein WASF3 isoform 1	WASF3	induces phosphorylation of	PubMed
actin nucleation-promoting factor WASL	WASL	inhibits	PubMed
Wilms tumor protein isoform A	WT1	downregulates	PubMed
lymphotactin precursor	XCL1	upregulates	PubMed
E3 ubiquitin-protein ligase XIAP	XIAP	increases	PubMed
exportin-T	XPOT	relocalized by	PubMed
Y-box-binding protein 1	YBX1	complexes with	PubMed
tyrosine-protein kinase ZAP-70 isoform 1	ZAP70	activates	PubMed
	ZAP70	inhibits	PubMed
	ZAP70	induces phosphorylation of	PubMed
zinc finger E-box-binding homeobox 1 isoform b	ZEB1	upregulates	PubMed
zinc finger RNA-binding protein	ZFR	complexes with	PubMed
zinc finger FYVE domain-containing protein 9 isoform 3	ZFYVE9	requires	PubMed
zyxin isoform 1	ZYX	interacts with	PubMed

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

General protein information

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Preferred Names: Nef

NP_057857.2

This particular nucleotide sequence has a premature stop codon in place of a well-conserved tryptophan codon at position 8712-8714 that truncates the HIV1 Nef protein sequence to a 123 amino acids-long N-terminal portion (not shown).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001802.1 Reference assembly

Range

8343..8963

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mRNA and Protein(s)

NP_057857.2 Nef [Human immunodeficiency virus 1]

See identical proteins and their annotated locations for NP_057857.2

Status: REVIEWED

UniProtKB/Swiss-Prot

O09780, P03406, P04601, Q85587

UniProtKB/TrEMBL

A0A6B9L1Z2

Conserved Domains (1) summary

pfam00469
Location:2 → 205

F-protein; Negative factor, (F-Protein) or Nef

Nucleotide		Protein
Heading	Accession and Version	Protein

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iRefWeb - iRefIndex release 9.0 - Consolidated Interactome

iRefWeb - iRefIndex release 9.0 - Consolidated Interactome

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nef Nef [ Human immunodeficiency virus 1 ]

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Genomic regions, transcripts, and products

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GeneRIFs: Gene References Into Functions

HIV-1 interactions

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Genes and mapped phenotypes

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nef Nef [ Human immunodeficiency virus 1 ]

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