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    CD36 CD36 molecule (CD36 blood group) [ Bos taurus (cattle) ]

    Gene ID: 281052, updated on 3-Apr-2024

    Summary

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    Gene symbol
    CD36
    Gene description
    CD36 molecule (CD36 blood group)
    See related
    BGD:BT10335; Ensembl:ENSBTAG00000017866
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    GPIV; PAS-4; GPIIIB
    Orthologs
    human mouse all
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    Genomic context

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    See CD36 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (40380301..40474070, complement)

    Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene platelet glycoprotein 4-like Neighboring gene CD36 molecule (thrombospondin receptor) Neighboring gene G protein subunit alpha transducin 3 Neighboring gene cullin-1-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. LTA recognition by bovine gammadelta T cells involves CD36. Lubick K, et al. J Leukoc Biol, 2006 Jun. PMID 16551677
    2. Assignment of disulfide bridges in bovine CD36. Rasmussen JT, et al. Eur J Biochem, 1998 Oct 15. PMID 9826197
    3. PAS IV, an integral membrane protein of mammary epithelial cells, is related to platelet and endothelial cell CD36 (GP IV). Greenwalt DE, et al. Biochemistry, 1990 Jul 31. PMID 1699598
    4. Structural, functional, and antigenic differences between bovine heart endothelial CD36 and human platelet CD36. Greenwalt DE, et al. J Biol Chem, 1990 Sep 25. PMID 1697855
    5. Obesity-driven prepartal hepatic lipid accumulation in dairy cows is associated with increased CD36 and SREBP-1 expression. Prodanović R, et al. Res Vet Sci, 2016 Aug. PMID 27473969

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables low-density lipoprotein particle binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables low-density lipoprotein particle receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables scavenger receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in amyloid-beta clearance by cellular catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid storage IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipoprotein transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in long-chain fatty acid import into cell IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in low-density lipoprotein particle clearance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in receptor-mediated endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in caveola IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    platelet glycoprotein 4
    Names
    CD36 antigen
    cluster of differentiation 36
    collagen type I receptor, thrombospondin receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001278621.1 → NP_001265550.1  platelet glycoprotein 4

      See identical proteins and their annotated locations for NP_001265550.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) resents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      BC103112, DV801272, NKLS02000004
      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7
      UniProtKB/TrEMBL
      G3MY21
      Conserved Domains (1) summary
      pfam01130
      Location:16 → 461
      CD36; CD36 family

    2. NM_174010.3 → NP_776435.2  platelet glycoprotein 4

      See identical proteins and their annotated locations for NP_776435.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      BC103112, DV842657, NKLS02000004
      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7
      UniProtKB/TrEMBL
      G3MY21
      Conserved Domains (1) summary
      pfam01130
      Location:16 → 461
      CD36; CD36 family

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      40380301..40474070 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059885384.1 → XP_059741367.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7

    2. XM_059885382.1 → XP_059741365.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7

    3. XM_005205326.5 → XP_005205383.1  platelet glycoprotein 4 isoform X1

      See identical proteins and their annotated locations for XP_005205383.1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7
      UniProtKB/TrEMBL
      G3MY21
      Related
      ENSBTAP00000023750.5, ENSBTAT00000023750.7
      Conserved Domains (1) summary
      pfam01130
      Location:16 → 461
      CD36; CD36 family

    4. XM_015468818.3 → XP_015324304.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7
      UniProtKB/TrEMBL
      G3MY21
      Conserved Domains (1) summary
      pfam01130
      Location:16 → 461
      CD36; CD36 family

    5. XM_024990428.2 → XP_024846196.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7
      UniProtKB/TrEMBL
      G3MY21
      Conserved Domains (1) summary
      pfam01130
      Location:16 → 461
      CD36; CD36 family

    6. XM_059885388.1 → XP_059741371.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7

    7. XM_059885389.1 → XP_059741372.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7

    8. XM_024990418.2 → XP_024846186.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7
      UniProtKB/TrEMBL
      G3MY21
      Conserved Domains (1) summary
      pfam01130
      Location:16 → 461
      CD36; CD36 family

    9. XM_059885381.1 → XP_059741364.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7

    10. XM_024990431.2 → XP_024846199.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7
      UniProtKB/TrEMBL
      G3MY21
      Conserved Domains (1) summary
      pfam01130
      Location:16 → 461
      CD36; CD36 family

    11. XM_015468812.3 → XP_015324298.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7
      UniProtKB/TrEMBL
      G3MY21
      Conserved Domains (1) summary
      pfam01130
      Location:16 → 461
      CD36; CD36 family

    12. XM_024990427.2 → XP_024846195.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7
      UniProtKB/TrEMBL
      G3MY21
      Conserved Domains (1) summary
      pfam01130
      Location:16 → 461
      CD36; CD36 family

    13. XM_024990421.2 → XP_024846189.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7
      UniProtKB/TrEMBL
      G3MY21
      Conserved Domains (1) summary
      pfam01130
      Location:16 → 461
      CD36; CD36 family

    14. XM_024990433.2 → XP_024846201.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7
      UniProtKB/TrEMBL
      G3MY21
      Conserved Domains (1) summary
      pfam01130
      Location:16 → 461
      CD36; CD36 family

    15. XM_024990419.2 → XP_024846187.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7
      UniProtKB/TrEMBL
      G3MY21
      Conserved Domains (1) summary
      pfam01130
      Location:16 → 461
      CD36; CD36 family

    16. XM_024990429.2 → XP_024846197.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7
      UniProtKB/TrEMBL
      G3MY21
      Conserved Domains (1) summary
      pfam01130
      Location:16 → 461
      CD36; CD36 family

    17. XM_059885383.1 → XP_059741366.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7

    18. XM_024990434.2 → XP_024846202.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7
      UniProtKB/TrEMBL
      G3MY21
      Conserved Domains (1) summary
      pfam01130
      Location:16 → 461
      CD36; CD36 family

    19. XM_059885386.1 → XP_059741369.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7

    20. XM_024990417.2 → XP_024846185.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7
      UniProtKB/TrEMBL
      G3MY21
      Conserved Domains (1) summary
      pfam01130
      Location:16 → 461
      CD36; CD36 family

    21. XM_024990430.2 → XP_024846198.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7
      UniProtKB/TrEMBL
      G3MY21
      Conserved Domains (1) summary
      pfam01130
      Location:16 → 461
      CD36; CD36 family

    22. XM_015468815.3 → XP_015324301.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7
      UniProtKB/TrEMBL
      G3MY21
      Conserved Domains (1) summary
      pfam01130
      Location:16 → 461
      CD36; CD36 family

    23. XM_059885387.1 → XP_059741370.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7

    24. XM_059885385.1 → XP_059741368.1  platelet glycoprotein 4 isoform X1

      UniProtKB/Swiss-Prot
      P26201, P79111, Q28154, Q3ZBT7
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P26201.5 GenPept UniProtKB/Swiss-Prot:P26201

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