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    AT5G40910 Disease resistance protein (TIR-NBS-LRR class) family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834092, updated on 15-Feb-2024

    Summary

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    Gene symbol
    AT5G40910
    Gene description
    Disease resistance protein (TIR-NBS-LRR class) family
    Primary source
    Araport:AT5G40910
    Locus tag
    AT5G40910
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MHK7.14; MHK7_14
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (16394462..16400489)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Nucleotide-diphospho-sugar transferase family protein Neighboring gene ncRNA Neighboring gene miscRNA Neighboring gene translocase of outer membrane 20-4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714
    2. Multi-omics network-based functional annotation of unknown Arabidopsis genes. Depuydt T, et al. Plant J, 2021 Nov. PMID 34562334

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_001344366.1
    NM_001344373.1
    NM_123456.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Disease resistance protein (TIR-NBS-LRR class) family
    NP_001318718.1
    • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: signal transduction, apoptosis, defense response, innate immune response; LOCATED IN: intrinsic to membrane; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT5G41550.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      16394462..16400489
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001344367.1 → NP_001330754.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBT0, Q8GZA0

    2. NM_001344368.1 → NP_001330755.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBT0, Q8GZA0

    3. NM_001344369.1 → NP_001330752.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBS3, Q8GZA0

    4. NM_001344370.1 → NP_001330753.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBT0, Q8GZA0

    5. NM_001344371.1 → NP_001330750.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBS3, Q8GZA0

    6. NM_001344372.1 → NP_001330751.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBT0, Q8GZA0

    7. NM_001344366.1 → NP_001318718.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178U7P4, Q9FKR7
      Conserved Domains (6) summary
      PLN03210
      Location:1 → 968
      PLN03210; Resistant to P. syringae 6; Provisional
      sd00033
      Location:588 → 610
      LRR_RI; leucine-rich repeat [structural motif]
      pfam01582
      Location:12 → 177
      TIR; TIR domain
      pfam07725
      Location:587 → 606
      LRR_3; Leucine Rich Repeat
      pfam13191
      Location:186 → 230
      AAA_16; AAA ATPase domain
      pfam13401
      Location:211 → 299
      AAA_22; AAA domain

    8. NM_001344373.1 → NP_001330749.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBT0, Q8GZA0

    9. NM_123456.1 → NP_198907.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_198907.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178U7P4, Q9FKR7
      Conserved Domains (6) summary
      PLN03210
      Location:1 → 968
      PLN03210; Resistant to P. syringae 6; Provisional
      sd00033
      Location:588 → 610
      LRR_RI; leucine-rich repeat [structural motif]
      pfam01582
      Location:12 → 177
      TIR; TIR domain
      pfam07725
      Location:587 → 606
      LRR_3; Leucine Rich Repeat
      pfam13191
      Location:186 → 230
      AAA_16; AAA ATPase domain
      pfam13401
      Location:211 → 299
      AAA_22; AAA domain
    Nucleotide Protein
    Heading Accession and Version

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