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dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs1805411

Current Build 155

Released April 9, 2021

Organism
Homo sapiens
Position
chr1:226390346 (GRCh38.p13) Help

The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.

Alleles
G>C / G>T
Variation Type
SNV Single Nucleotide Variation
Frequency
T=0.152583 (29714/194740, ALFA)
T=0.40137 (6727/16760, 8.3KJPN)
T=0.2103 (1053/5008, 1000G) (+ 16 more)
T=0.1819 (815/4480, Estonian)
T=0.1583 (610/3854, ALSPAC)
T=0.1467 (544/3708, TWINSUK)
T=0.4505 (1320/2930, KOREAN)
T=0.2601 (542/2084, HGDP_Stanford)
T=0.2035 (385/1892, HapMap)
T=0.4552 (834/1832, Korea1K)
T=0.191 (191/998, GoNL)
T=0.268 (161/600, NorthernSweden)
T=0.112 (60/534, MGP)
G=0.384 (96/250, SGDP_PRJ)
T=0.162 (35/216, Qatari)
T=0.410 (87/212, Vietnamese)
T=0.08 (6/76, Ancient Sardinia)
T=0.25 (10/40, GENOME_DK)
G=0.46 (11/24, Siberian)
Clinical Significance
Not Reported in ClinVar
Gene : Consequence
PARP1 : Intron Variant
Publications
1 citation
Genomic View
See rs on genome
Help

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements
Sequence name Change
GRCh38.p13 chr 1 NC_000001.11:g.226390346G>C
GRCh38.p13 chr 1 NC_000001.11:g.226390346G>T
GRCh37.p13 chr 1 NC_000001.10:g.226578047G>C
GRCh37.p13 chr 1 NC_000001.10:g.226578047G>T
Gene: PARP1, poly(ADP-ribose) polymerase 1 (minus strand)
Molecule type Change Amino acid[Codon] SO Term
PARP1 transcript NM_001618.4:c.617+64C>G N/A Intron Variant
Help

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20201027095038
Population Group Sample Size Ref Allele Alt Allele
Total Global 194740 G=0.847417 C=0.000000, T=0.152583
European Sub 172758 G=0.847179 C=0.000000, T=0.152821
African Sub 6578 G=0.9386 C=0.0000, T=0.0614
African Others Sub 248 G=0.972 C=0.000, T=0.028
African American Sub 6330 G=0.9373 C=0.0000, T=0.0627
Asian Sub 630 G=0.611 C=0.000, T=0.389
East Asian Sub 496 G=0.613 C=0.000, T=0.387
Other Asian Sub 134 G=0.604 C=0.000, T=0.396
Latin American 1 Sub 748 G=0.846 C=0.000, T=0.154
Latin American 2 Sub 2472 G=0.6820 C=0.0000, T=0.3180
South Asian Sub 5028 G=0.8866 C=0.0000, T=0.1134
Other Sub 6526 G=0.8172 C=0.0000, T=0.1828


Help

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

Download
Study Population Group Sample Size Ref Allele Alt Allele
Allele Frequency Aggregator Total Global 194740 G=0.847417 C=0.000000, T=0.152583
Allele Frequency Aggregator European Sub 172758 G=0.847179 C=0.000000, T=0.152821
Allele Frequency Aggregator African Sub 6578 G=0.9386 C=0.0000, T=0.0614
Allele Frequency Aggregator Other Sub 6526 G=0.8172 C=0.0000, T=0.1828
Allele Frequency Aggregator South Asian Sub 5028 G=0.8866 C=0.0000, T=0.1134
Allele Frequency Aggregator Latin American 2 Sub 2472 G=0.6820 C=0.0000, T=0.3180
Allele Frequency Aggregator Latin American 1 Sub 748 G=0.846 C=0.000, T=0.154
Allele Frequency Aggregator Asian Sub 630 G=0.611 C=0.000, T=0.389
8.3KJPN JAPANESE Study-wide 16760 G=0.59863 T=0.40137
1000Genomes Global Study-wide 5008 G=0.7897 T=0.2103
1000Genomes African Sub 1322 G=0.9130 T=0.0870
1000Genomes East Asian Sub 1008 G=0.5635 T=0.4365
1000Genomes Europe Sub 1006 G=0.8459 T=0.1541
1000Genomes South Asian Sub 978 G=0.900 T=0.100
1000Genomes American Sub 694 G=0.647 T=0.353
Genetic variation in the Estonian population Estonian Study-wide 4480 G=0.8181 T=0.1819
The Avon Longitudinal Study of Parents and Children PARENT AND CHILD COHORT Study-wide 3854 G=0.8417 T=0.1583
UK 10K study - Twins TWIN COHORT Study-wide 3708 G=0.8533 T=0.1467
KOREAN population from KRGDB KOREAN Study-wide 2930 G=0.5495 C=0.0000, T=0.4505
HGDP-CEPH-db Supplement 1 Global Study-wide 2084 G=0.7399 T=0.2601
HGDP-CEPH-db Supplement 1 Est_Asia Sub 470 G=0.577 T=0.423
HGDP-CEPH-db Supplement 1 Central_South_Asia Sub 414 G=0.819 T=0.181
HGDP-CEPH-db Supplement 1 Middle_Est Sub 350 G=0.886 T=0.114
HGDP-CEPH-db Supplement 1 Europe Sub 320 G=0.853 T=0.147
HGDP-CEPH-db Supplement 1 Africa Sub 242 G=0.855 T=0.145
HGDP-CEPH-db Supplement 1 America Sub 216 G=0.412 T=0.588
HGDP-CEPH-db Supplement 1 Oceania Sub 72 G=0.74 T=0.26
HapMap Global Study-wide 1892 G=0.7965 T=0.2035
HapMap American Sub 770 G=0.764 T=0.236
HapMap African Sub 692 G=0.900 T=0.100
HapMap Asian Sub 254 G=0.547 T=0.453
HapMap Europe Sub 176 G=0.892 T=0.108
Korean Genome Project KOREAN Study-wide 1832 G=0.5448 T=0.4552
Genome of the Netherlands Release 5 Genome of the Netherlands Study-wide 998 G=0.809 T=0.191
Northern Sweden ACPOP Study-wide 600 G=0.732 T=0.268
Medical Genome Project healthy controls from Spanish population Spanish controls Study-wide 534 G=0.888 T=0.112
SGDP_PRJ Global Study-wide 250 G=0.384 T=0.616
Qatari Global Study-wide 216 G=0.838 T=0.162
A Vietnamese Genetic Variation Database Global Study-wide 212 G=0.590 T=0.410
Ancient Sardinia genome-wide 1240k capture data generation and analysis Global Study-wide 76 G=0.92 T=0.08
The Danish reference pan genome Danish Study-wide 40 G=0.75 T=0.25
Siberian Global Study-wide 24 G=0.46 T=0.54
Help

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement G= C T
GRCh38.p13 chr 1 NC_000001.11:g.226390346= NC_000001.11:g.226390346G>C NC_000001.11:g.226390346G>T
GRCh37.p13 chr 1 NC_000001.10:g.226578047= NC_000001.10:g.226578047G>C NC_000001.10:g.226578047G>T
PARP1 transcript NM_001618.3:c.617+64= NM_001618.3:c.617+64C>G NM_001618.3:c.617+64C>A
PARP1 transcript NM_001618.4:c.617+64= NM_001618.4:c.617+64C>G NM_001618.4:c.617+64C>A
Help

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

107 SubSNP, 23 Frequency submissions
No Submitter Submission ID Date (Build)
1 UWGC ss2667856 Jan 12, 2001 (92)
2 HGBASE ss3182323 Aug 15, 2001 (98)
3 YUSUKE ss3236514 Sep 28, 2001 (100)
4 SC_JCM ss3609404 Sep 28, 2001 (100)
5 EGP_SNPS ss4480418 Jul 03, 2002 (106)
6 SNP500CANCER ss5586201 Mar 31, 2003 (113)
7 IMCJ-GDT ss22886552 Apr 05, 2004 (121)
8 ABI ss43937950 Mar 13, 2006 (126)
9 ILLUMINA ss66772922 Nov 30, 2006 (127)
10 ILLUMINA ss67197163 Nov 30, 2006 (127)
11 ILLUMINA ss67586300 Nov 30, 2006 (127)
12 ILLUMINA ss70675373 May 24, 2008 (130)
13 ILLUMINA ss71238396 May 17, 2007 (127)
14 ILLUMINA ss75803153 Dec 07, 2007 (129)
15 CGM_KYOTO ss76874611 Dec 07, 2007 (129)
16 ILLUMINA ss79094343 Dec 15, 2007 (130)
17 KRIBB_YJKIM ss83877973 Dec 15, 2007 (130)
18 CNG ss95213709 Mar 25, 2008 (129)
19 BGI ss106636545 Feb 05, 2009 (130)
20 1000GENOMES ss108999516 Jan 23, 2009 (130)
21 ILLUMINA ss121814835 Dec 01, 2009 (131)
22 ILLUMINA ss153737345 Dec 01, 2009 (131)
23 ILLUMINA ss159329926 Dec 01, 2009 (131)
24 ILLUMINA ss160463336 Dec 01, 2009 (131)
25 COMPLETE_GENOMICS ss167543503 Jul 04, 2010 (132)
26 ILLUMINA ss170816226 Jul 04, 2010 (132)
27 ILLUMINA ss172926753 Jul 04, 2010 (132)
28 1000GENOMES ss218916104 Jul 14, 2010 (132)
29 1000GENOMES ss230928901 Jul 14, 2010 (132)
30 1000GENOMES ss238536671 Jul 15, 2010 (132)
31 BL ss253867741 May 09, 2011 (134)
32 GMI ss276244188 May 04, 2012 (137)
33 ILLUMINA ss480301907 May 04, 2012 (137)
34 ILLUMINA ss480312974 May 04, 2012 (137)
35 ILLUMINA ss481069134 Sep 08, 2015 (146)
36 ILLUMINA ss484948743 May 04, 2012 (137)
37 ILLUMINA ss536992717 Sep 08, 2015 (146)
38 TISHKOFF ss555178924 Apr 25, 2013 (138)
39 SSMP ss648750602 Apr 25, 2013 (138)
40 ILLUMINA ss778841634 Sep 08, 2015 (146)
41 ILLUMINA ss782920678 Sep 08, 2015 (146)
42 ILLUMINA ss783883683 Sep 08, 2015 (146)
43 ILLUMINA ss825424861 Apr 01, 2015 (144)
44 ILLUMINA ss832175808 Sep 08, 2015 (146)
45 ILLUMINA ss832841935 Jul 12, 2019 (153)
46 ILLUMINA ss834302193 Sep 08, 2015 (146)
47 EVA-GONL ss976213765 Aug 21, 2014 (142)
48 JMKIDD_LAB ss1068654016 Aug 21, 2014 (142)
49 1000GENOMES ss1294912117 Aug 21, 2014 (142)
50 EVA_GENOME_DK ss1574721924 Apr 01, 2015 (144)
51 EVA_DECODE ss1585611692 Apr 01, 2015 (144)
52 EVA_UK10K_ALSPAC ss1602279440 Apr 01, 2015 (144)
53 EVA_UK10K_TWINSUK ss1645273473 Apr 01, 2015 (144)
54 EVA_MGP ss1710945844 Apr 01, 2015 (144)
55 EVA_SVP ss1712410443 Apr 01, 2015 (144)
56 ILLUMINA ss1751902330 Sep 08, 2015 (146)
57 HAMMER_LAB ss1795818643 Sep 08, 2015 (146)
58 WEILL_CORNELL_DGM ss1919435822 Feb 12, 2016 (147)
59 GENOMED ss1966989387 Jul 19, 2016 (147)
60 JJLAB ss2020242375 Sep 14, 2016 (149)
61 USC_VALOUEV ss2148276693 Dec 20, 2016 (150)
62 HUMAN_LONGEVITY ss2170629140 Dec 20, 2016 (150)
63 TOPMED ss2333270122 Dec 20, 2016 (150)
64 SYSTEMSBIOZJU ss2624632476 Nov 08, 2017 (151)
65 ILLUMINA ss2632637655 Nov 08, 2017 (151)
66 ILLUMINA ss2635007946 Nov 08, 2017 (151)
67 GRF ss2698274890 Nov 08, 2017 (151)
68 GNOMAD ss2766965716 Nov 08, 2017 (151)
69 SWEGEN ss2988559599 Nov 08, 2017 (151)
70 BIOINF_KMB_FNS_UNIBA ss3023881594 Nov 08, 2017 (151)
71 TOPMED ss3105114686 Nov 08, 2017 (151)
72 TOPMED ss3105114687 Nov 08, 2017 (151)
73 CSHL ss3343943031 Nov 08, 2017 (151)
74 ILLUMINA ss3626323427 Oct 11, 2018 (152)
75 ILLUMINA ss3630667056 Oct 11, 2018 (152)
76 ILLUMINA ss3632927916 Oct 11, 2018 (152)
77 ILLUMINA ss3633624053 Oct 11, 2018 (152)
78 ILLUMINA ss3634376197 Oct 11, 2018 (152)
79 ILLUMINA ss3635317105 Oct 11, 2018 (152)
80 ILLUMINA ss3636055064 Oct 11, 2018 (152)
81 ILLUMINA ss3637067655 Oct 11, 2018 (152)
82 ILLUMINA ss3637817930 Oct 11, 2018 (152)
83 ILLUMINA ss3638924086 Oct 11, 2018 (152)
84 ILLUMINA ss3639460980 Oct 11, 2018 (152)
85 ILLUMINA ss3640083550 Oct 11, 2018 (152)
86 ILLUMINA ss3642824014 Oct 11, 2018 (152)
87 OMUKHERJEE_ADBS ss3646254276 Oct 11, 2018 (152)
88 EGCUT_WGS ss3656518555 Jul 12, 2019 (153)
89 EVA_DECODE ss3688758575 Jul 12, 2019 (153)
90 ACPOP ss3727920092 Jul 12, 2019 (153)
91 ILLUMINA ss3744677050 Jul 12, 2019 (153)
92 EVA ss3747417455 Jul 12, 2019 (153)
93 ILLUMINA ss3772177942 Jul 12, 2019 (153)
94 KHV_HUMAN_GENOMES ss3800420297 Jul 12, 2019 (153)
95 EVA ss3825589463 Apr 25, 2020 (154)
96 EVA ss3826678117 Apr 25, 2020 (154)
97 EVA ss3836741118 Apr 25, 2020 (154)
98 EVA ss3842153381 Apr 25, 2020 (154)
99 HGDP ss3847365585 Apr 25, 2020 (154)
100 SGDP_PRJ ss3851034824 Apr 25, 2020 (154)
101 KRGDB ss3896371552 Apr 25, 2020 (154)
102 KOGIC ss3946626801 Apr 25, 2020 (154)
103 FSA-LAB ss3983965163 Apr 25, 2021 (155)
104 EVA ss3984856065 Apr 25, 2021 (155)
105 TOPMED ss4485897219 Apr 25, 2021 (155)
106 TOPMED ss4485897220 Apr 25, 2021 (155)
107 TOMMO_GENOMICS ss5148735260 Apr 25, 2021 (155)
108 1000Genomes NC_000001.10 - 226578047 Oct 11, 2018 (152)
109 The Avon Longitudinal Study of Parents and Children NC_000001.10 - 226578047 Oct 11, 2018 (152)
110 Genetic variation in the Estonian population NC_000001.10 - 226578047 Oct 11, 2018 (152)
111 The Danish reference pan genome NC_000001.10 - 226578047 Apr 25, 2020 (154)
112 gnomAD - Genomes

Submission ignored due to conflicting rows:
Row 41486974 (NC_000001.11:226390345:G:C 1/140088)
Row 41486975 (NC_000001.11:226390345:G:T 23793/140054)

- Apr 25, 2021 (155)
113 gnomAD - Genomes

Submission ignored due to conflicting rows:
Row 41486974 (NC_000001.11:226390345:G:C 1/140088)
Row 41486975 (NC_000001.11:226390345:G:T 23793/140054)

- Apr 25, 2021 (155)
114 Genome of the Netherlands Release 5 NC_000001.10 - 226578047 Apr 25, 2020 (154)
115 HGDP-CEPH-db Supplement 1 NC_000001.9 - 224644670 Apr 25, 2020 (154)
116 HapMap NC_000001.11 - 226390346 Apr 25, 2020 (154)
117 KOREAN population from KRGDB NC_000001.10 - 226578047 Apr 25, 2020 (154)
118 Korean Genome Project NC_000001.11 - 226390346 Apr 25, 2020 (154)
119 Medical Genome Project healthy controls from Spanish population NC_000001.10 - 226578047 Apr 25, 2020 (154)
120 Northern Sweden NC_000001.10 - 226578047 Jul 12, 2019 (153)
121 Ancient Sardinia genome-wide 1240k capture data generation and analysis NC_000001.10 - 226578047 Apr 25, 2021 (155)
122 Qatari NC_000001.10 - 226578047 Apr 25, 2020 (154)
123 SGDP_PRJ NC_000001.10 - 226578047 Apr 25, 2020 (154)
124 Siberian NC_000001.10 - 226578047 Apr 25, 2020 (154)
125 8.3KJPN NC_000001.10 - 226578047 Apr 25, 2021 (155)
126 TopMed

Submission ignored due to conflicting rows:
Row 49503554 (NC_000001.11:226390345:G:C 2/264690)
Row 49503555 (NC_000001.11:226390345:G:T 47181/264690)

- Apr 25, 2021 (155)
127 TopMed

Submission ignored due to conflicting rows:
Row 49503554 (NC_000001.11:226390345:G:C 2/264690)
Row 49503555 (NC_000001.11:226390345:G:T 47181/264690)

- Apr 25, 2021 (155)
128 UK 10K study - Twins NC_000001.10 - 226578047 Oct 11, 2018 (152)
129 A Vietnamese Genetic Variation Database NC_000001.10 - 226578047 Jul 12, 2019 (153)
130 ALFA NC_000001.11 - 226390346 Apr 25, 2021 (155)
Help

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID History Updated (Build)
rs58493729 May 24, 2008 (130)
Added to this RefSNP Cluster:
Submission IDs Observation SPDI Canonical SPDI Source RSIDs
3548946, ss3896371552 NC_000001.10:226578046:G:C NC_000001.11:226390345:G:C (self)
352105967, ss3105114686, ss4485897219 NC_000001.11:226390345:G:C NC_000001.11:226390345:G:C (self)
ss3638924086, ss3639460980 NC_000001.8:222884781:G:T NC_000001.11:226390345:G:T (self)
43477, ss108999516, ss167543503, ss253867741, ss276244188, ss480301907, ss825424861, ss1585611692, ss1712410443, ss2635007946, ss3642824014, ss3847365585 NC_000001.9:224644669:G:T NC_000001.11:226390345:G:T (self)
5776209, 3192355, 2256803, 1913185, 1395083, 3548946, 62596, 1204957, 81992, 1477752, 3051804, 793047, 6704567, 3192355, 693344, ss218916104, ss230928901, ss238536671, ss480312974, ss481069134, ss484948743, ss536992717, ss555178924, ss648750602, ss778841634, ss782920678, ss783883683, ss832175808, ss832841935, ss834302193, ss976213765, ss1068654016, ss1294912117, ss1574721924, ss1602279440, ss1645273473, ss1710945844, ss1751902330, ss1795818643, ss1919435822, ss1966989387, ss2020242375, ss2148276693, ss2333270122, ss2624632476, ss2632637655, ss2698274890, ss2766965716, ss2988559599, ss3343943031, ss3626323427, ss3630667056, ss3632927916, ss3633624053, ss3634376197, ss3635317105, ss3636055064, ss3637067655, ss3637817930, ss3640083550, ss3646254276, ss3656518555, ss3727920092, ss3744677050, ss3747417455, ss3772177942, ss3825589463, ss3826678117, ss3836741118, ss3851034824, ss3896371552, ss3983965163, ss3984856065, ss5148735260 NC_000001.10:226578046:G:T NC_000001.11:226390345:G:T (self)
282201, 3004802, 31109229, 352105967, ss2170629140, ss3023881594, ss3105114687, ss3688758575, ss3800420297, ss3842153381, ss3946626801, ss4485897220 NC_000001.11:226390345:G:T NC_000001.11:226390345:G:T (self)
ss2667856, ss3182323, ss3236514, ss3609404, ss4480418, ss5586201, ss22886552, ss43937950, ss66772922, ss67197163, ss67586300, ss70675373, ss71238396, ss75803153, ss76874611, ss79094343, ss83877973, ss95213709, ss106636545, ss121814835, ss153737345, ss159329926, ss160463336, ss170816226, ss172926753 NT_167186.1:20095825:G:T NC_000001.11:226390345:G:T (self)
Help

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

1 citation for rs1805411
PMID Title Author Year Journal
21487324 Genetic effects and modifiers of radiotherapy and chemotherapy on survival in pancreatic cancer. Zeng H et al. 2011 Pancreas
Help

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:
Select flank length:

Genomic regions, transcripts, and products
Top Help

NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

Software version is: 2.0.1.post596+ae089ad