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dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs2072661

Current Build 155

Released April 9, 2021

Organism
Homo sapiens
Position
chr1:154576404 (GRCh38.p13) Help

The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.

Alleles
G>A
Variation Type
SNV Single Nucleotide Variation
Frequency
A=0.250739 (66368/264690, TOPMED)
A=0.254952 (35705/140046, GnomAD)
A=0.27199 (21315/78366, PAGE_STUDY) (+ 16 more)
A=0.24719 (7083/28654, ALFA)
A=0.27160 (4552/16760, 8.3KJPN)
A=0.2646 (1325/5008, 1000G)
A=0.2098 (940/4480, Estonian)
A=0.2439 (940/3854, ALSPAC)
A=0.2330 (864/3708, TWINSUK)
A=0.2679 (785/2930, KOREAN)
A=0.2942 (539/1832, Korea1K)
A=0.253 (252/998, GoNL)
A=0.285 (225/790, PRJEB37584)
A=0.312 (187/600, NorthernSweden)
G=0.367 (83/226, SGDP_PRJ)
A=0.241 (52/216, Qatari)
A=0.290 (62/214, Vietnamese)
A=0.23 (9/40, GENOME_DK)
G=0.38 (12/32, Siberian)
Clinical Significance
Reported in ClinVar
Gene : Consequence
CHRNB2 : Non Coding Transcript Variant
Publications
25 citations
Genomic View
See rs on genome
Help

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements
Sequence name Change
GRCh38.p13 chr 1 NC_000001.11:g.154576404G>A
GRCh37.p13 chr 1 NC_000001.10:g.154548880G>A
CHRNB2 RefSeqGene NG_008027.1:g.13624G>A
Gene: CHRNB2, cholinergic receptor nicotinic beta 2 subunit (plus strand)
Molecule type Change Amino acid[Codon] SO Term
CHRNB2 transcript NM_000748.3:c.*472= N/A 3 Prime UTR Variant
CHRNB2 transcript variant X2 XM_017000180.2:c.*472= N/A 3 Prime UTR Variant
CHRNB2 transcript variant X1 XR_001736952.2:n.2233G>A N/A Non Coding Transcript Variant
Help

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Allele: A (allele ID: 362494 )
ClinVar Accession Disease Names Clinical Significance
RCV000417150.1 nicotine response - Efficacy, Toxicity/ADR Drug-Response

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20201027095038
Population Group Sample Size Ref Allele Alt Allele
Total Global 28654 G=0.75281 A=0.24719
European Sub 20536 G=0.76539 A=0.23461
African Sub 6012 G=0.7101 A=0.2899
African Others Sub 198 G=0.722 A=0.278
African American Sub 5814 G=0.7097 A=0.2903
Asian Sub 146 G=0.671 A=0.329
East Asian Sub 120 G=0.658 A=0.342
Other Asian Sub 26 G=0.73 A=0.27
Latin American 1 Sub 146 G=0.788 A=0.212
Latin American 2 Sub 610 G=0.775 A=0.225
South Asian Sub 104 G=0.808 A=0.192
Other Sub 1100 G=0.7400 A=0.2600


Help

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

Download
Study Population Group Sample Size Ref Allele Alt Allele
TopMed Global Study-wide 264690 G=0.749261 A=0.250739
gnomAD - Genomes Global Study-wide 140046 G=0.745048 A=0.254952
gnomAD - Genomes European Sub 75858 G=0.75263 A=0.24737
gnomAD - Genomes African Sub 41954 G=0.71972 A=0.28028
gnomAD - Genomes American Sub 13642 G=0.76858 A=0.23142
gnomAD - Genomes Ashkenazi Jewish Sub 3322 G=0.8116 A=0.1884
gnomAD - Genomes East Asian Sub 3122 G=0.7268 A=0.2732
gnomAD - Genomes Other Sub 2148 G=0.7463 A=0.2537
The PAGE Study Global Study-wide 78366 G=0.72801 A=0.27199
The PAGE Study AfricanAmerican Sub 32376 G=0.72279 A=0.27721
The PAGE Study Mexican Sub 10762 G=0.79047 A=0.20953
The PAGE Study Asian Sub 8276 G=0.7466 A=0.2534
The PAGE Study PuertoRican Sub 7890 G=0.7349 A=0.2651
The PAGE Study NativeHawaiian Sub 4510 G=0.4958 A=0.5042
The PAGE Study Cuban Sub 4218 G=0.7572 A=0.2428
The PAGE Study Dominican Sub 3814 G=0.7336 A=0.2664
The PAGE Study CentralAmerican Sub 2444 G=0.7778 A=0.2222
The PAGE Study SouthAmerican Sub 1972 G=0.7429 A=0.2571
The PAGE Study NativeAmerican Sub 1256 G=0.7444 A=0.2556
The PAGE Study SouthAsian Sub 848 G=0.751 A=0.249
Allele Frequency Aggregator Total Global 28654 G=0.75281 A=0.24719
Allele Frequency Aggregator European Sub 20536 G=0.76539 A=0.23461
Allele Frequency Aggregator African Sub 6012 G=0.7101 A=0.2899
Allele Frequency Aggregator Other Sub 1100 G=0.7400 A=0.2600
Allele Frequency Aggregator Latin American 2 Sub 610 G=0.775 A=0.225
Allele Frequency Aggregator Latin American 1 Sub 146 G=0.788 A=0.212
Allele Frequency Aggregator Asian Sub 146 G=0.671 A=0.329
Allele Frequency Aggregator South Asian Sub 104 G=0.808 A=0.192
8.3KJPN JAPANESE Study-wide 16760 G=0.72840 A=0.27160
1000Genomes Global Study-wide 5008 G=0.7354 A=0.2646
1000Genomes African Sub 1322 G=0.7179 A=0.2821
1000Genomes East Asian Sub 1008 G=0.6825 A=0.3175
1000Genomes Europe Sub 1006 G=0.7326 A=0.2674
1000Genomes South Asian Sub 978 G=0.798 A=0.202
1000Genomes American Sub 694 G=0.762 A=0.238
Genetic variation in the Estonian population Estonian Study-wide 4480 G=0.7902 A=0.2098
The Avon Longitudinal Study of Parents and Children PARENT AND CHILD COHORT Study-wide 3854 G=0.7561 A=0.2439
UK 10K study - Twins TWIN COHORT Study-wide 3708 G=0.7670 A=0.2330
KOREAN population from KRGDB KOREAN Study-wide 2930 G=0.7321 A=0.2679
Korean Genome Project KOREAN Study-wide 1832 G=0.7058 A=0.2942
Genome of the Netherlands Release 5 Genome of the Netherlands Study-wide 998 G=0.747 A=0.253
CNV burdens in cranial meningiomas Global Study-wide 790 G=0.715 A=0.285
CNV burdens in cranial meningiomas CRM Sub 790 G=0.715 A=0.285
Northern Sweden ACPOP Study-wide 600 G=0.688 A=0.312
SGDP_PRJ Global Study-wide 226 G=0.367 A=0.633
Qatari Global Study-wide 216 G=0.759 A=0.241
A Vietnamese Genetic Variation Database Global Study-wide 214 G=0.710 A=0.290
The Danish reference pan genome Danish Study-wide 40 G=0.78 A=0.23
Siberian Global Study-wide 32 G=0.38 A=0.62
Help

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement G= A
GRCh38.p13 chr 1 NC_000001.11:g.154576404= NC_000001.11:g.154576404G>A
GRCh37.p13 chr 1 NC_000001.10:g.154548880= NC_000001.10:g.154548880G>A
CHRNB2 RefSeqGene NG_008027.1:g.13624= NG_008027.1:g.13624G>A
CHRNB2 transcript NM_000748.3:c.*472= NM_000748.3:c.*472G>A
CHRNB2 transcript NM_000748.2:c.*472= NM_000748.2:c.*472G>A
CHRNB2 transcript variant X2 XM_017000180.2:c.*472= XM_017000180.2:c.*472G>A
CHRNB2 transcript variant X1 XR_001736952.2:n.2233= XR_001736952.2:n.2233G>A
Help

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

79 SubSNP, 19 Frequency, 1 ClinVar submissions
No Submitter Submission ID Date (Build)
1 YUSUKE ss2986746 Jun 15, 2001 (96)
2 HGBASE ss3187719 Aug 15, 2001 (98)
3 WI_SSAHASNP ss6693695 Feb 20, 2003 (111)
4 ABI ss43847675 Mar 13, 2006 (126)
5 TAPPERS ss69371818 May 16, 2007 (127)
6 SI_EXO ss71641908 May 16, 2007 (127)
7 UUGC ss76901691 Dec 06, 2007 (129)
8 HGSV ss78839079 Dec 06, 2007 (129)
9 HUMANGENOME_JCVI ss99251112 Feb 05, 2009 (130)
10 SHGC ss99307547 Feb 05, 2009 (130)
11 1000GENOMES ss111154447 Jan 25, 2009 (130)
12 ILLUMINA-UK ss119032247 Feb 15, 2009 (130)
13 ENSEMBL ss131695553 Dec 01, 2009 (131)
14 GMI ss155752759 Dec 01, 2009 (131)
15 PERLEGEN ss161151673 Dec 01, 2009 (131)
16 COMPLETE_GENOMICS ss164120040 Jul 04, 2010 (132)
17 COMPLETE_GENOMICS ss167133563 Jul 04, 2010 (132)
18 BUSHMAN ss199086367 Jul 04, 2010 (132)
19 1000GENOMES ss218651248 Jul 14, 2010 (132)
20 1000GENOMES ss230731931 Jul 14, 2010 (132)
21 1000GENOMES ss238379843 Jul 15, 2010 (132)
22 GMI ss276051214 May 04, 2012 (137)
23 GMI ss284152643 Apr 25, 2013 (138)
24 PJP ss290637059 May 09, 2011 (134)
25 ILLUMINA ss482106421 May 04, 2012 (137)
26 ILLUMINA ss483384405 May 04, 2012 (137)
27 GSK-GENETICS ss491235561 May 04, 2012 (137)
28 ILLUMINA ss535597172 Sep 08, 2015 (146)
29 TISHKOFF ss554693768 Apr 25, 2013 (138)
30 SSMP ss648413996 Apr 25, 2013 (138)
31 ILLUMINA ss782135377 Sep 08, 2015 (146)
32 ILLUMINA ss834975894 Sep 08, 2015 (146)
33 EVA-GONL ss975682560 Aug 21, 2014 (142)
34 JMKIDD_LAB ss1068269623 Aug 21, 2014 (142)
35 1000GENOMES ss1292925502 Aug 21, 2014 (142)
36 DDI ss1425978967 Apr 01, 2015 (144)
37 EVA_GENOME_DK ss1574392085 Apr 01, 2015 (144)
38 EVA_DECODE ss1585063978 Apr 01, 2015 (144)
39 EVA_UK10K_ALSPAC ss1601213929 Apr 01, 2015 (144)
40 EVA_UK10K_TWINSUK ss1644207962 Apr 01, 2015 (144)
41 HAMMER_LAB ss1795092188 Sep 08, 2015 (146)
42 WEILL_CORNELL_DGM ss1918916464 Feb 12, 2016 (147)
43 ILLUMINA ss1958317578 Feb 12, 2016 (147)
44 JJLAB ss2019973770 Sep 14, 2016 (149)
45 USC_VALOUEV ss2147998284 Dec 20, 2016 (150)
46 HUMAN_LONGEVITY ss2166540960 Dec 20, 2016 (150)
47 TOPMED ss2329045880 Dec 20, 2016 (150)
48 ILLUMINA ss2632576062 Nov 08, 2017 (151)
49 GRF ss2697971175 Nov 08, 2017 (151)
50 GNOMAD ss2761315616 Nov 08, 2017 (151)
51 AFFY ss2984879305 Nov 08, 2017 (151)
52 AFFY ss2985525066 Nov 08, 2017 (151)
53 SWEGEN ss2987752072 Nov 08, 2017 (151)
54 ILLUMINA ss3021136273 Nov 08, 2017 (151)
55 BIOINF_KMB_FNS_UNIBA ss3023744053 Nov 08, 2017 (151)
56 TOPMED ss3092142273 Nov 08, 2017 (151)
57 CSHL ss3343710532 Nov 08, 2017 (151)
58 ILLUMINA ss3626208406 Oct 11, 2018 (152)
59 ILLUMINA ss3630608957 Oct 11, 2018 (152)
60 OMUKHERJEE_ADBS ss3646246101 Oct 11, 2018 (152)
61 URBANLAB ss3646791325 Oct 11, 2018 (152)
62 ILLUMINA ss3651470517 Oct 11, 2018 (152)
63 ILLUMINA ss3653648500 Oct 11, 2018 (152)
64 EGCUT_WGS ss3655692287 Jul 12, 2019 (153)
65 EVA_DECODE ss3687782305 Jul 12, 2019 (153)
66 ILLUMINA ss3725065373 Jul 12, 2019 (153)
67 ACPOP ss3727485706 Jul 12, 2019 (153)
68 EVA ss3746808075 Jul 12, 2019 (153)
69 PAGE_CC ss3770840931 Jul 12, 2019 (153)
70 KHV_HUMAN_GENOMES ss3799809812 Jul 12, 2019 (153)
71 EVA ss3825575807 Apr 25, 2020 (154)
72 EVA ss3826424136 Apr 25, 2020 (154)
73 SGDP_PRJ ss3850006603 Apr 25, 2020 (154)
74 KRGDB ss3895212941 Apr 25, 2020 (154)
75 KOGIC ss3945651170 Apr 25, 2020 (154)
76 FSA-LAB ss3983947187 Apr 25, 2021 (155)
77 EVA ss3984464755 Apr 25, 2021 (155)
78 TOPMED ss4468301372 Apr 25, 2021 (155)
79 TOMMO_GENOMICS ss5146483013 Apr 25, 2021 (155)
80 1000Genomes NC_000001.10 - 154548880 Oct 11, 2018 (152)
81 The Avon Longitudinal Study of Parents and Children NC_000001.10 - 154548880 Oct 11, 2018 (152)
82 Genetic variation in the Estonian population NC_000001.10 - 154548880 Oct 11, 2018 (152)
83 The Danish reference pan genome NC_000001.10 - 154548880 Apr 25, 2020 (154)
84 gnomAD - Genomes NC_000001.11 - 154576404 Apr 25, 2021 (155)
85 Genome of the Netherlands Release 5 NC_000001.10 - 154548880 Apr 25, 2020 (154)
86 KOREAN population from KRGDB NC_000001.10 - 154548880 Apr 25, 2020 (154)
87 Korean Genome Project NC_000001.11 - 154576404 Apr 25, 2020 (154)
88 Northern Sweden NC_000001.10 - 154548880 Jul 12, 2019 (153)
89 The PAGE Study NC_000001.11 - 154576404 Jul 12, 2019 (153)
90 CNV burdens in cranial meningiomas NC_000001.10 - 154548880 Apr 25, 2021 (155)
91 Qatari NC_000001.10 - 154548880 Apr 25, 2020 (154)
92 SGDP_PRJ NC_000001.10 - 154548880 Apr 25, 2020 (154)
93 Siberian NC_000001.10 - 154548880 Apr 25, 2020 (154)
94 8.3KJPN NC_000001.10 - 154548880 Apr 25, 2021 (155)
95 TopMed NC_000001.11 - 154576404 Apr 25, 2021 (155)
96 UK 10K study - Twins NC_000001.10 - 154548880 Oct 11, 2018 (152)
97 A Vietnamese Genetic Variation Database NC_000001.10 - 154548880 Jul 12, 2019 (153)
98 ALFA NC_000001.11 - 154576404 Apr 25, 2021 (155)
99 ClinVar RCV000417150.1 Oct 11, 2018 (152)
Help

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Added to this RefSNP Cluster:
Submission IDs Observation SPDI Canonical SPDI Source RSIDs
ss78839079 NC_000001.8:151361952:G:A NC_000001.11:154576403:G:A (self)
ss111154447, ss119032247, ss164120040, ss167133563, ss199086367, ss276051214, ss284152643, ss290637059, ss482106421, ss491235561, ss1585063978 NC_000001.9:152815503:G:A NC_000001.11:154576403:G:A (self)
3717555, 2021158, 1430535, 1708642, 878201, 2390335, 770571, 14069, 958394, 2023583, 514638, 4452320, 2021158, 434386, ss218651248, ss230731931, ss238379843, ss483384405, ss535597172, ss554693768, ss648413996, ss782135377, ss834975894, ss975682560, ss1068269623, ss1292925502, ss1425978967, ss1574392085, ss1601213929, ss1644207962, ss1795092188, ss1918916464, ss1958317578, ss2019973770, ss2147998284, ss2329045880, ss2632576062, ss2697971175, ss2761315616, ss2984879305, ss2985525066, ss2987752072, ss3021136273, ss3343710532, ss3626208406, ss3630608957, ss3646246101, ss3651470517, ss3653648500, ss3655692287, ss3727485706, ss3746808075, ss3825575807, ss3826424136, ss3850006603, ss3895212941, ss3983947187, ss3984464755, ss5146483013 NC_000001.10:154548879:G:A NC_000001.11:154576403:G:A (self)
RCV000417150.1, 27050457, 2029171, 62400, 20031770, 31907707, 579534791, ss2166540960, ss3023744053, ss3092142273, ss3646791325, ss3687782305, ss3725065373, ss3770840931, ss3799809812, ss3945651170, ss4468301372 NC_000001.11:154576403:G:A NC_000001.11:154576403:G:A (self)
ss2986746, ss3187719, ss6693695, ss43847675, ss69371818, ss71641908, ss76901691, ss99251112, ss99307547, ss131695553, ss155752759, ss161151673 NT_004487.19:6037521:G:A NC_000001.11:154576403:G:A (self)
Help

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

25 citations for rs2072661
PMID Title Author Year Journal
15154117 A common haplotype of the nicotine acetylcholine receptor alpha 4 subunit gene is associated with vulnerability to nicotine addiction in men. Feng Y et al. 2004 American journal of human genetics
17503330 A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence. Lou XY et al. 2007 American journal of human genetics
18165968 Identification of pharmacogenetic markers in smoking cessation therapy. Heitjan DF et al. 2008 American journal of medical genetics. Part B, Neuropsychiatric genetics
18534558 Gene-gene interactions among CHRNA4, CHRNB2, BDNF, and NTRK2 in nicotine dependence. Li MD et al. 2008 Biological psychiatry
18593715 Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation. Conti DV et al. 2008 Human molecular genetics
19238175 New insights into the genetics of addiction. Li MD et al. 2009 Nature reviews. Genetics
19482438 Association of genes coding for the alpha-4, alpha-5, beta-2 and beta-3 subunits of nicotinic receptors with cigarette smoking and nicotine dependence. Etter JF et al. 2009 Addictive behaviors
19755656 Nicotinic acetylcholine receptor beta2 subunit (CHRNB2) gene and short-term ability to quit smoking in response to nicotine patch. Perkins KA et al. 2009 Cancer epidemiology, biomarkers & prevention
19859904 Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans. Li MD et al. 2010 American journal of medical genetics. Part B, Neuropsychiatric genetics
20736995 Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerström test for nicotine dependence. Wessel J et al. 2010 Neuropsychopharmacology
20854418 CHRNB2 promoter region: association with subjective effects to nicotine and gene expression differences. Hoft NR et al. 2011 Genes, brain, and behavior
20981002 Breaking barriers in the genomics and pharmacogenetics of drug addiction. Ho MK et al. 2010 Clinical pharmacology and therapeutics
21606948 Varenicline for smoking cessation: nausea severity and variation in nicotinic receptor genes. Swan GE et al. 2012 The pharmacogenomics journal
21808284 Gender-stratified gene and gene-treatment interactions in smoking cessation. Lee W et al. 2012 The pharmacogenomics journal
22103610 Biomarkers to optimize the treatment of nicotine dependence. Schnoll RA et al. 2011 Biomarkers in medicine
22180580 Association between nicotinic acetylcholine receptor single nucleotide polymorphisms and smoking cessation. Spruell T et al. 2012 Nicotine & tobacco research
22290489 Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes. Gold AB et al. 2012 Human genetics
22992668 Pharmacogenomics knowledge for personalized medicine. Whirl-Carrillo M et al. 2012 Clinical pharmacology and therapeutics
23249876 Nicotinic acetylcholine receptor variation and response to smoking cessation therapies. Bergen AW et al. 2013 Pharmacogenetics and genomics
23691092 Associations of prenatal nicotine exposure and the dopamine related genes ANKK1 and DRD2 to verbal language. Eicher JD et al. 2013 PloS one
23943838 Effect of neuronal nicotinic acetylcholine receptor genes (CHRN) on longitudinal cigarettes per day in adolescents and young adults. Cannon DS et al. 2014 Nicotine & tobacco research
24667010 Nicotine dependence as a moderator of genetic influences on smoking cessation treatment outcome. Leventhal AM et al. 2014 Drug and alcohol dependence
25036316 Joint association of nicotinic acetylcholine receptor variants with abdominal obesity in American Indians: the Strong Heart Family Study. Zhu Y et al. 2014 PloS one
25778907 The DYX2 locus and neurochemical signaling genes contribute to speech sound disorder and related neurocognitive domains. Eicher JD et al. 2015 Genes, brain, and behavior
25819021 A review of pharmacogenetic studies of substance-related disorders. Jones JD et al. 2015 Drug and alcohol dependence
Help

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:
Select flank length:

Genomic regions, transcripts, and products
Top Help

NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

Software version is: 2.0.1.post596+ae089ad