Illumina HiSeq 2000 paired end sequencing of SAMD00425690 - SRA

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DRX320668: Illumina HiSeq 2000 paired end sequencing of SAMD00425690
1 ILLUMINA (Illumina HiSeq 2000) run: 21.9M spots, 4.3G bases, 1.9Gb downloads

Submitted by: OSAKA_WPI

Study: sCTLA-4 and mCTLA-4 functions in immune homeostasis

PRJDB12679 • DRP007957 • All experiments • All runs

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CTLA-4 is the immunosuppressive molecule to prevent autoimmune and immunopathological diseases. Both soluble (sCTLA-4) and membrane (mCTLA-4) forms bind to the same ligands (CD80/86) on antigen presenting cells to regulate a quantity of the CD80/86 co-stimulation for T cells. The mCTLA-4 function has been extensively investigated in the field of autoimmunity and cancer immunotherapy. In this study, we characterized the sCTLA-4 function during chronic inflammation, distinguishing it from the function of mCTLA-4 using sCTLA-4-intact mCTLA-4-deficient (S+M-) mice compared with double-deficient mice (S-M-).

Sample: RNA-seq of macrophage (S+M+) replicate 1

SAMD00425690 • DRS212572 • All experiments • All runs

Organism: Mus musculus

Library:

Name: RNAseq_macrophage_S+M+_rep1

Instrument: Illumina HiSeq 2000

Strategy: RNA-Seq

Source: TRANSCRIPTOMIC

Selection: cDNA

Layout: PAIRED

Construction protocol: Illumina TruSeq RNA Sample Preparation Kit

Spot descriptor:

1 forward101 reverse

Runs: 1 run, 21.9M spots, 4.3G bases, 1.9Gb

Run	# of Spots	# of Bases	Size	Published
DRR331664	21,936,469	4.3G	1.9Gb	2021-12-05

ID:: 18247081

SRA

Sequence Read Archive

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