show Abstracthide AbstractMicrosatellite instability (MSI) and tumor mutational burden (TMB) are indicators of the tumor mutational load, which can lead to immune cell recruitment. By contrast, the number of tumor-infiltrating T cells (TITs) is indicative of the host immune response to tumor cells. The present study evaluated if the expression of mismatch repair (MMR) proteins can be used as a precise tool to assess immunogenicity in the tumor microenvironment, which was performed using TIT (counting CD3+ and CD8+ cells in a tumor ) analyses and TMB tests (the total number of variants found in the DNA of cancer cells)