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SRX7443224: GSM4233266: WT-P6-1; Mus musculus; RNA-Seq
1 ILLUMINA (Illumina HiSeq 3000) run: 33.1M spots, 1.6G bases, 633.8Mb downloads

Submitted by: NCBI (GEO)
Study: Transcriptome of Immortalized Mouse Corneal Endothelial Cells with SLC4A11 deficiency
show Abstracthide Abstract
Mutations in the solute-linked carrier family 4 member 11 (SLC4A11) gene are associated with several corneal endothelial dystrophies, in all of which visually significant cornea edema may require corneal transplantation. To elucidate the pathogenesis of SLC4A11 associated corneal endothelial dystrophies, we analyzed the transcriptome of immortalized mouse corneal endothelial cells (Slc4a11-/- MCEnC) and Slc4a11+/+ MCEnC as controls. Overall design: Slc4a11-/- MCEnC P7 (n=3) vs Slc4a11+/+ MCEnC P6 (n=3); Slc4a11-/- MCEnC P40 (n=3) vs Slc4a11+/+ MCEnC P39 (n=3).
Sample: WT-P6-1
SAMN13683651 • SRS5887522 • All experiments • All runs
Organism: Mus musculus
Instrument: Illumina HiSeq 3000
Strategy: RNA-Seq
Selection: cDNA
Layout: SINGLE
Construction protocol: Total RNA from cultured MCEnC was isolated and purified using the RNeasy Plus Mini Kit (Qiagen). UCLA TCGB protocol
Experiment attributes:
GEO Accession: GSM4233266
Runs: 1 run, 33.1M spots, 1.6G bases, 633.8Mb
Run# of Spots# of BasesSizePublished


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