GSM4233265: KO-P40-3; Mus musculus; RNA-Seq - SRA

SRX7443223: GSM4233265: KO-P40-3; Mus musculus; RNA-Seq
1 ILLUMINA (Illumina HiSeq 3000) run: 26M spots, 1.3G bases, 497.6Mb downloads

Submitted by: NCBI (GEO)

Study: Transcriptome of Immortalized Mouse Corneal Endothelial Cells with SLC4A11 deficiency

PRJNA597783 • SRP238853 • All experiments • All runs

show Abstracthide Abstract

Mutations in the solute-linked carrier family 4 member 11 (SLC4A11) gene are associated with several corneal endothelial dystrophies, in all of which visually significant cornea edema may require corneal transplantation. To elucidate the pathogenesis of SLC4A11 associated corneal endothelial dystrophies, we analyzed the transcriptome of immortalized mouse corneal endothelial cells (Slc4a11-/- MCEnC) and Slc4a11+/+ MCEnC as controls. Overall design: Slc4a11-/- MCEnC P7 (n=3) vs Slc4a11+/+ MCEnC P6 (n=3); Slc4a11-/- MCEnC P40 (n=3) vs Slc4a11+/+ MCEnC P39 (n=3).

Sample: KO-P40-3

SAMN13683652 • SRS5887521 • All experiments • All runs

Organism: Mus musculus

Library:

Instrument: Illumina HiSeq 3000

Strategy: RNA-Seq

Source: TRANSCRIPTOMIC

Selection: cDNA

Layout: SINGLE

Construction protocol: Total RNA from cultured MCEnC was isolated and purified using the RNeasy Plus Mini Kit (Qiagen). UCLA TCGB protocol

Experiment attributes:

GEO Accession: GSM4233265

Links:

NCBI link: NCBI Entrez (gds)

Runs: 1 run, 26M spots, 1.3G bases, 497.6Mb

Run	# of Spots	# of Bases	Size	Published
SRR10769305	26,009,270	1.3G	497.6Mb	2020-08-13

ID:: 9735112

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