GSM3181859: MS645_50_rep0; Homo sapiens; RNA-Seq - SRA

SRX4190668: GSM3181859: MS645_50_rep0; Homo sapiens; RNA-Seq
1 ILLUMINA (Illumina HiSeq 2000) run: 48.8M spots, 4.9G bases, 2.1Gb downloads

Submitted by: NCBI (GEO)

Study: Spatially Constrained Tandem Bromodomain Inhibition Bolsters Sustained Repression of BRD4 Transcriptional Activity for TNBC Cell Growth

PRJNA475425 • SRP150159 • All experiments • All runs

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We performed RNA-seq of MDA-MB-231 cells that were treated with MS645 or JQ1 at 50 nM and 500 nM in an effort to understand how MS645 exerts such a profound cell growth inhibition on cancer cells. Overall design: MDA-MB-231 cells were treated with DMSO and different concentrations of JQ1 and MS645 for 18 hrs to compare the compounds' effect in transcriptional regulation.

Sample: MS645_50_rep0

SAMN09389060 • SRS3401905 • All experiments • All runs

Organism: Homo sapiens

Library:

Instrument: Illumina HiSeq 2000

Strategy: RNA-Seq

Source: TRANSCRIPTOMIC

Selection: cDNA

Layout: SINGLE

Construction protocol: Total RNA was extracted using NucleoSpin® RNA (Macherey-Nagel). RNA libraries were prepared for sequencing using standard Illumina protocols by sequencing cores.

Experiment attributes:

GEO Accession: GSM3181859

Links:

NCBI link: NCBI Entrez (gds)

Runs: 1 run, 48.8M spots, 4.9G bases, 2.1Gb

Run	# of Spots	# of Bases	Size	Published
SRR7287128	48,798,626	4.9G	2.1Gb	2018-08-31

ID:: 5677462

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Sequence Read Archive

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