National Center for
Biotechnology Information

5A2Q: Structure of the HCV IRES bound to the human ribosome

PDB ID:

MMDB ID:

131009

PDB Deposition Date:

2015/5/21

Updated in MMDB:

2019/12

Experimental Method:

electron microscopy

Resolution:

3.9 Å

Source Organism:

Hepacivirus hominis▼

Taxonomy	Molecule
Hepacivirus hominis	3
Homo sapiens	2, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d, e, f, g , h, r, w

Similar Structures:

Biological Unit for 5A2Q: 38-meric; determined by author and by software (PISA)

Molecular Components in 5A2Q
Label	Count	Molecule
Proteins (36 molecules)
A	1	Ribosomal Protein US2
B	1	Ribosomal Protein ES1
C	1	Ribosomal Protein US5
D	1	Ribosomal Protein US3
E	1	Ribosomal Protein ES4
F	1	Ribosomal Protein US7
G	1	Ribosomal Protein ES6
H	1	Ribosomal Protein ES7
I	1	Ribosomal Protein ES8
J	1	Ribosomal Protein US4
K	1	Ribosomal Protein Es10
L	1	Ribosomal Protein Us17
M	1	Ribosomal Protein Es12
N	1	Ribosomal Protein Us15
O	1	Ribosomal Protein Us11
P	1	Ribosomal Protein Us19
Q	1	Ribosomal Protein US9
R	1	Ribosomal Protein Es17
S	1	Ribosomal Protein Us13
T	1	Ribosomal Protein Es19
U	1	Ribosomal Protein Us10
V	1	Ribosomal Protein Es21
W	1	Ribosomal Protein US8
X	1	Ribosomal Protein Us12
Y	1	Ribosomal Protein Es24
Z	1	Ribosomal Protein Es25
a	1	Ribosomal Protein Es26
b	1	Ribosomal Protein Es27
c	1	Ribosomal Protein Es28
d	1	Ribosomal Protein Us14
e	1	Ribosomal Protein Es30
f	1	Ribosomal Protein Es31
g	1	Ribosomal Protein Rack1
h	1	Ribosomal Protein El41
r	1	Ribosomal Protein El19
w	1	Ribosomal Protein El24
Nucleotides(2 molecules)
2	1	18S rRNA
3	1	HCV Ires
Chemicals and Non-standard biopolymers (101 molecules)
1	98	MAGNESIUM ION (Link to PubChem not yet available)
2	3	ZINC ION (Link to PubChem not yet available)

* Click molecule labels to explore molecular sequence information.

Citing MMDB