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5MAH:
Crystal structure of MELK in complex with an inhibitor
PDB ID:
5MAH
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MMDB ID:
156921
PDB Deposition Date:
2016/11/3
Updated in MMDB:
2017/12
Experimental Method:
x-ray diffraction
Resolution:
2 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 5MAH: monomeric; determined by author and by software (PISA)
Molecular Components in 5MAH
Label
Count
Molecule
Protein (1 molecule)
A
1
Maternal Embryonic Leucine Zipper Kinase
(Gene symbol:
MELK
)
Chemicals and Non-standard biopolymers (5 molecules)
1
1
~{N}-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide
2
1
GLYCEROL
3
1
CHLORIDE ION
4
2
SODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303