8X93: P/Q type calcium channel in complex with omega-Agatoxin IVA

PDB ID: 8X93Download
MMDB ID: 244417
PDB Deposition Date: 2023/11/29
Updated in MMDB: 2024/03
Experimental Method:
electron microscopy
Resolution: 2.92  Å
Source Organism:
Similar Structures:
Biological Unit for 8X93: trimeric; determined by author and by software
Molecular Components in 8X93
Label Count Molecule
Proteins (3 molecules)
1
Voltage-dependent L-type Calcium Channel Subunit Beta-3
(Gene symbol: CACNB3)
Molecule annotation
1
Voltage-dependent Calcium Channel Subunit Alpha-2/delta-1
(Gene symbol: CACNA2D1)
Molecule annotation
1
Voltage-dependent P/q-type Calcium Channel Subunit Alpha-1a
(Gene symbol: CACNA1A)
Molecule annotation
Chemicals and Non-standard biopolymers (28 molecules)
1
15
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
3
CALCIUM IONCALCIUM ION
3
5
CHOLESTEROLCHOLESTEROL
4
1
[(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate[(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate
5
3
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
6
1
1,2-Distearoyl-sn-glycerophosphoethanolamine1,2-Distearoyl-sn-glycerophosphoethanolamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303