7MRD: Crystal structure of the first bromodomain (BD1) of human BRDT bound to GXH-II-082

PDB ID: 7MRDDownload
MMDB ID: 215477
PDB Deposition Date: 2021/5/7
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.39  Å
Source Organism:
Similar Structures:
Biological Unit for 7MRD: monomeric; determined by author and by software (PISA)
Molecular Components in 7MRD
Label Count Molecule
Protein (1 molecule)
1
Bromodomain Testis-specific Protein
(Gene symbol: BRDT)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N,N'-[(1,16-dioxo-4,7,10,13-tetraoxahexadecane-1,16-diyl)di(piperidine-1,4-diyl)]bis{4-[(4-{4-chloro-3-[(2-methylpropane-2-sulfonyl)amino]anilino}-5-methylpyrimidin-2-yl)amino]-2-fluorobenzamide}N,N'-[(1,16-dioxo-4,7,10,13-tetraoxahexadecane-1,16-diyl)di(piperidine-1,4-diyl)]bis{4-[(4-{4-chloro-3-[(2-methylpropane-2-sulfonyl)amino]anilino}-5-methylpyrimidin-2-yl)amino]-2-fluorobenzamide}
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303