1LYA: CRYSTAL STRUCTURES OF NATIVE AND INHIBITED FORMS OF HUMAN CATHEPSIN D: IMPLICATIONS FOR LYSOSOMAL TARGETING AND DRUG DESIGN

PDB ID: 1LYADownload
MMDB ID: 1596
PDB Deposition Date: 1993/4/22
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 1LYA: tetrameric; determined by author
Molecular Components in 1LYA
Label Count Molecule
Proteins (4 molecules)
2
Cathepsin D
(Gene symbol: CTSD)
Molecule annotation
2
Cathepsin D
(Gene symbol: CTSD)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
6
N-ACETYL-D-GLUCOSAMINEN-ACETYL-D-GLUCOSAMINE
2
2
BETA-D-MANNOSEBETA-D-MANNOSE
3
2
ALPHA-D-MANNOSEALPHA-D-MANNOSE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303