2FHH: Crystal Structure of Mycobacterium Tuberculosis Proteasome in complex with a peptidyl boronate inhibitor MLN-273

PDB ID: 2FHHDownload
MMDB ID: 37744
PDB Deposition Date: 2005/12/23
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 2.99  Å
Source Organism:
Similar Structures:
Biological Unit for 2FHH: 28-meric; determined by author and by software (PISA)
Molecular Components in 2FHH
Label Count Molecule
Proteins (28 molecules)
14
20S Proteasome, Alpha and Beta Subunits
Molecule annotation
14
Proteasome, Beta Subunit
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
14
(1R)-3-METHYL-1-{[N-(MORPHOLIN-4-YLCARBONYL)-3-(1-NAPHTHYL)-D-ALANYL]AMINO}BUTYLBORONIC ACID(1R)-3-METHYL-1-{[N-(MORPHOLIN-4-YLCARBONYL)-3-(1-NAPHTHYL)-D-ALANYL]AMINO}BUTYLBORONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303