GEO Accession viewer

NCBI > GEO > Accession Display

Not logged in | Login

GEO help: Mouse over screen elements for information.

Series GSE4

Query DataSets for GSE4

Status

Public on Jul 20, 2001

Title

Diurnal and Circadian-Regulated Genes in Arabidopsis

Organism

Arabidopsis thaliana

Experiment type

Expression profiling by array

Summary

Plants respond to day/night cycling in a number of physiological ways. At the mRNA level, the expression of some genes changes during the 24-hr period. To identify novel genes regulated in this way, we used microarrays containing 11,521 Arabidopsis expressed sequence tags, representing an estimated 7800 unique genes, to determine gene expression levels at 6-hr intervals throughout the day. Eleven percent of the genes, encompassing genes expressed at both high and low levels, showed a diurnal expression pattern. Approximately 2% cycled with a circadian rhythm. By clustering microarray data from 47 additional, unrelated experiments, we identified groups of genes regulated only by the circadian clock. These groups contained the already characterized clock-associated genes LHY, CCA1, and GI, suggesting that other key circadian clock genes might be found within these clusters.
This research has been described more fully in Schaffer R et al.(2001) Plant Cell 13:113-123
Keywords = circadian rhythm
Keywords: other

Contributor(s)

Schaffer R, Landgraf J, Accerbi M, Simon V, Larson M, Wisman E

Citation(s)

11158533

Submission date

Jul 20, 2001

Last update date

Feb 23, 2012

Organization

Stanford Microarray Database (SMD)

E-mail(s)

array@genome.stanford.edu