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Series GSE42078 Query DataSets for GSE42078
Status Public on Feb 16, 2013
Title Expression data of differentiated human erythroid cells with or without Tranylcypromine (TC) treatment
Organism Homo sapiens
Experiment type Expression profiling by array
Summary We found that LSD1 inhibition by a monoamine oxidase inhibitor, tranylcypromine (TC), could enhance fetal gamma globin expression.
Global effects of TC on erythroid expession were conducted by HG-U219 array strips.
 
Overall design Primary human erythroid cells, which differentiated from CD34+ cells for 8 days, were harvested before or and after TC treatment (0.5 µM, 1.5 µM or 5 µM) for the gene expression analysis.
 
Contributor(s) Shi L, Cui S, Engel JD, Tanabe O
Citation(s) 23416702
Submission date Nov 06, 2012
Last update date Mar 21, 2019
Contact name Lihong Shi
E-mail(s) shilh@med.umich.edu
Organization name University of Michigan
Street address 3608 BSRB, 109 Zina Pitcher Place
City Ann Arbor
ZIP/Postal code 48109
Country USA
 
Platforms (1)
GPL13667 [HG-U219] Affymetrix Human Genome U219 Array
Samples (4)
GSM1032112 without TC treatment
GSM1032113 TC-0.5 µM treament
GSM1032114 TC-1.5 µM treament
Relations
BioProject PRJNA179085

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE42078_RAW.tar 9.0 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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