|
| Status |
Public on Feb 16, 2013 |
| Title |
Expression data of differentiated human erythroid cells with or without Tranylcypromine (TC) treatment |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We found that LSD1 inhibition by a monoamine oxidase inhibitor, tranylcypromine (TC), could enhance fetal gamma globin expression.
Global effects of TC on erythroid expession were conducted by HG-U219 array strips.
|
| |
|
| Overall design |
Primary human erythroid cells, which differentiated from CD34+ cells for 8 days, were harvested before or and after TC treatment (0.5 µM, 1.5 µM or 5 µM) for the gene expression analysis.
|
| |
|
| Contributor(s) |
Shi L, Cui S, Engel JD, Tanabe O |
| Citation(s) |
23416702 |
| Submission date |
Nov 06, 2012 |
| Last update date |
Mar 21, 2019 |
| Contact name |
Lihong Shi |
| E-mail(s) |
shilh@med.umich.edu
|
| Organization name |
University of Michigan
|
| Street address |
3608 BSRB, 109 Zina Pitcher Place
|
| City |
Ann Arbor |
| ZIP/Postal code |
48109 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13667 |
[HG-U219] Affymetrix Human Genome U219 Array |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA179085 |
Less...
More...