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Status |
Public on Feb 16, 2013 |
Title |
Expression data of differentiated human erythroid cells with or without Tranylcypromine (TC) treatment |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
We found that LSD1 inhibition by a monoamine oxidase inhibitor, tranylcypromine (TC), could enhance fetal gamma globin expression. Global effects of TC on erythroid expession were conducted by HG-U219 array strips.
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Overall design |
Primary human erythroid cells, which differentiated from CD34+ cells for 8 days, were harvested before or and after TC treatment (0.5 µM, 1.5 µM or 5 µM) for the gene expression analysis.
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Contributor(s) |
Shi L, Cui S, Engel JD, Tanabe O |
Citation(s) |
23416702 |
Submission date |
Nov 06, 2012 |
Last update date |
Mar 21, 2019 |
Contact name |
Lihong Shi |
E-mail(s) |
shilh@med.umich.edu
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Organization name |
University of Michigan
|
Street address |
3608 BSRB, 109 Zina Pitcher Place
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City |
Ann Arbor |
ZIP/Postal code |
48109 |
Country |
USA |
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Platforms (1) |
GPL13667 |
[HG-U219] Affymetrix Human Genome U219 Array |
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Samples (4)
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Relations |
BioProject |
PRJNA179085 |