|
| Status |
Public on Sep 17, 2013 |
| Title |
The effects of dietary selenium on selenocysteine incorporation and selenoprotein expression |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The goal of this study was to determine the effects of dietary selenium levels on translational control of selenoprotein synthesis in mouse liver.
|
| |
|
| Overall design |
Wild type mice and mice expressing a mutant Sec-tRNA gene (TrspA37G) were fed diets supplemented with 0, 0.1, or 2 ppm selenium for 6 weeks. Livers were harvested and ribosome and mRNA profiles were generated by deep-sequencing using the Illumina HiSeq 2000.
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| |
|
| Contributor(s) |
Howard MT |
| Citation(s) |
23696641 |
| Submission date |
Apr 13, 2013 |
| Last update date |
May 15, 2019 |
| Contact name |
Michael T Howard |
| E-mail(s) |
mhoward@genetics.utah.edu
|
| Phone |
801-585-1927
|
| Organization name |
University of Utah
|
| Department |
Human Genetics
|
| Lab |
Howard
|
| Street address |
15 N 2030 E
|
| City |
Salt Lake City |
| State/province |
UT |
| ZIP/Postal code |
84112 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA197001 |
| SRA |
SRP021058 |
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