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| Status |
Public on May 03, 2017 |
| Title |
Genome wide STAT3 RNAi expression profiling data from Thp,Th0 and Th17 cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
STAT3 is an immidiate regulator of Th17 differentiation. STAT3 difieciency downmodulate Th17 specific genes and Th17 responses. Therefore, we intend to identify genome wide targets of STAT3.
We used microarrays to profile gene expression of STAT3 regulated genes during Th17 polarization.
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| Overall design |
Total RNA was extracted from non-targeting and STAT3 siRNA treated Thp, Th0 and Th17 cell samples from different time points. Total RNA subjected to poly-A selection and hybridization on Affymetrix microarrays.
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| Contributor(s) |
Tripathi S, Lahesmaa R |
| Citation(s) |
28564606 |
| Submission date |
Mar 23, 2015 |
| Last update date |
Mar 21, 2019 |
| Contact name |
Tarmo Äijö |
| Organization name |
Flatiron Institute
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| Department |
Center for Computational Biology
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| Street address |
162 5th Avenue
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| City |
New York |
| ZIP/Postal code |
10010 |
| Country |
USA |
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| Platforms (1) |
| GPL13667 |
[HG-U219] Affymetrix Human Genome U219 Array |
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| Samples (108)
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| GSM1641346 |
Th0, 12h, scramble, repl. 1 |
| GSM1641347 |
Th0, 24h, D1 siRNA, repl. 1 |
| GSM1641348 |
Th0, 24h, D2 siRNA, repl. 1 |
| GSM1641349 |
Th0, 24h, S2 siRNA, repl. 1 |
| GSM1641350 |
Th0, 24h, scramble, repl. 1 |
| GSM1641351 |
Th0, 2h, D1 siRNA, repl. 1 |
| GSM1641352 |
Th0, 2h, D2 siRNA, repl. 1 |
| GSM1641353 |
Th0, 2h, S2 siRNA, repl. 1 |
| GSM1641354 |
Th0, 2h, scramble, repl. 1 |
| GSM1641355 |
Th0, 72h, D1 siRNA, repl. 1 |
| GSM1641356 |
Th0, 72h, D2 siRNA, repl. 1 |
| GSM1641357 |
Th0, 72h, S2 siRNA, repl. 1 |
| GSM1641358 |
Th0, 72h, scramble, repl. 1 |
| GSM1641359 |
Th17, 12h, D1 siRNA, repl. 1 |
| GSM1641360 |
Th17, 12h, D2 siRNA, repl. 1 |
| GSM1641361 |
Th17, 12h, S2 siRNA, repl. 1 |
| GSM1641362 |
Th17, 12h, scramble, repl. 1 |
| GSM1641363 |
Th17, 24h, D1 siRNA, repl. 1 |
| GSM1641364 |
Th17, 24h, D2 siRNA, repl. 1 |
| GSM1641365 |
Th17, 24h, S2 siRNA, repl. 1 |
| GSM1641366 |
Th17, 24h, scramble, repl. 1 |
| GSM1641367 |
Th17, 2h, D1 siRNA, repl. 1 |
| GSM1641368 |
Th17, 2h, D2 siRNA, repl. 1 |
| GSM1641369 |
Th17, 2h, S2 siRNA, repl. 1 |
| GSM1641370 |
Th17, 2h, scramble, repl. 1 |
| GSM1641371 |
Th17, 72h, D1 siRNA, repl. 1 |
| GSM1641372 |
Th17, 72h, D2 siRNA, repl. 1 |
| GSM1641373 |
Th17, 72h, S2 siRNA, repl. 1 |
| GSM1641374 |
Th17, 72h, scramble, repl. 1 |
| GSM1641375 |
Thp, 0h, D1 siRNA, repl. 1 |
| GSM1641376 |
Thp, 0h, D2 siRNA, repl. 1 |
| GSM1641377 |
Thp, 0h, S2 siRNA, repl. 1 |
| GSM1641378 |
Thp, 0h, scramble, repl. 1 |
| GSM1641379 |
Th0, 12h, D1 siRNA, repl. 2 |
| GSM1641380 |
Th0, 12h, D2 siRNA, repl. 2 |
| GSM1641381 |
Th0, 12h, S2 siRNA, repl. 2 |
| GSM1641382 |
Th0, 12h, scramble, repl. 2 |
| GSM1641383 |
Th0, 24h, D1 siRNA, repl. 2 |
| GSM1641384 |
Th0, 24h, D2 siRNA, repl. 2 |
| GSM1641385 |
Th0, 24h, S2 siRNA, repl. 2 |
| GSM1641386 |
Th0, 24h, scramble, repl. 2 |
| GSM1641387 |
Th0, 2h, D1 siRNA, repl. 2 |
| GSM1641388 |
Th0, 2h, D2 siRNA, repl. 2 |
| GSM1641389 |
Th0, 2h, S2 siRNA, repl. 2 |
| GSM1641390 |
Th0, 2h, scramble, repl. 2 |
| GSM1641391 |
Th0, 72h, D1 siRNA, repl. 2 |
| GSM1641392 |
Th0, 72h, D2 siRNA, repl. 2 |
| GSM1641393 |
Th0, 72h, S2 siRNA, repl. 2 |
| GSM1641394 |
Th0, 72h, scramble, repl. 2 |
| GSM1641395 |
Th17, 12h, D1 siRNA, repl. 2 |
| GSM1641396 |
Th17, 12h, D2 siRNA, repl. 2 |
| GSM1641397 |
Th17, 12h, S2 siRNA, repl. 2 |
| GSM1641398 |
Th17, 12h, scramble, repl. 2 |
| GSM1641399 |
Th17, 24h, D1 siRNA, repl. 2 |
| GSM1641400 |
Th17, 24h, D2 siRNA, repl. 2 |
| GSM1641401 |
Th17, 24h, S2 siRNA, repl. 2 |
| GSM1641402 |
Th17, 24h, scramble, repl. 2 |
| GSM1641403 |
Th17, 2h, D1 siRNA, repl. 2 |
| GSM1641404 |
Th17, 2h, D2 siRNA, repl. 2 |
| GSM1641405 |
Th17, 2h, S2 siRNA, repl. 2 |
| GSM1641406 |
Th17, 2h, scramble, repl. 2 |
| GSM1641407 |
Th17, 72h, D1 siRNA, repl. 2 |
| GSM1641408 |
Th17, 72h, D2 siRNA, repl. 2 |
| GSM1641409 |
Th17, 72h, S2 siRNA, repl. 2 |
| GSM1641410 |
Th17, 72h, scramble, repl. 2 |
| GSM1641411 |
Thp, 0h, D1 siRNA, repl. 2 |
| GSM1641412 |
Thp, 0h, D2 siRNA, repl. 2 |
| GSM1641413 |
Thp, 0h, S2 siRNA, repl. 2 |
| GSM1641414 |
Thp, 0h, scramble, repl. 2 |
| GSM1641415 |
Th0, 12h, D1 siRNA, repl. 3 |
| GSM1641416 |
Th0, 12h, D2 siRNA, repl. 3 |
| GSM1641417 |
Th0, 12h, S2 siRNA, repl. 3 |
| GSM1641418 |
Th0, 12h, scramble, repl. 3 |
| GSM1641419 |
Th0, 24h, D1 siRNA, repl. 3 |
| GSM1641420 |
Th0, 24h, D2 siRNA, repl. 3 |
| GSM1641421 |
Th0, 24h, S2 siRNA, repl. 3 |
| GSM1641422 |
Th0, 24h, scramble, repl. 3 |
| GSM1641423 |
Th0, 2h, D1 siRNA, repl. 3 |
| GSM1641424 |
Th0, 2h, D2 siRNA, repl. 3 |
| GSM1641425 |
Th0, 2h, S2 siRNA, repl. 3 |
| GSM1641426 |
Th0, 2h, scramble, repl. 3 |
| GSM1641427 |
Th0, 72h, D1 siRNA, repl. 3 |
| GSM1641428 |
Th0, 72h, D2 siRNA, repl. 3 |
| GSM1641429 |
Th0, 72h, S2 siRNA, repl. 3 |
| GSM1641430 |
Th0, 72h, scramble, repl. 3 |
| GSM1641431 |
Th17, 12h, D1 siRNA, repl. 3 |
| GSM1641432 |
Th17, 12h, D2 siRNA, repl. 3 |
| GSM1641433 |
Th17, 12h, S2 siRNA, repl. 3 |
| GSM1641434 |
Th17, 12h, scramble, repl. 3 |
| GSM1641435 |
Th17, 24h, D1 siRNA, repl. 3 |
| GSM1641436 |
Th17, 24h, D2 siRNA, repl. 3 |
| GSM1641437 |
Th17, 24h, S2 siRNA, repl. 3 |
| GSM1641438 |
Th17, 24h, scramble, repl. 3 |
| GSM1641439 |
Th17, 2h, D1 siRNA, repl. 3 |
| GSM1641440 |
Th17, 2h, D2 siRNA, repl. 3 |
| GSM1641441 |
Th17, 2h, S2 siRNA, repl. 3 |
| GSM1641442 |
Th17, 2h, scramble, repl. 3 |
| GSM1641443 |
Th17, 72h, D1 siRNA, repl. 3 |
| GSM1641444 |
Th17, 72h, D2 siRNA, repl. 3 |
| GSM1641445 |
Th17, 72h, S2 siRNA, repl. 3 |
| GSM1641446 |
Th17, 72h, scramble, repl. 3 |
| GSM1641447 |
Thp, 0h, D1 siRNA, repl. 3 |
| GSM1641448 |
Thp, 0h, D2 siRNA, repl. 3 |
| GSM1641449 |
Thp, 0h, S2 siRNA, repl. 3 |
| GSM1641450 |
Thp, 0h, scramble, repl. 3 |
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| Relations |
| BioProject |
PRJNA279202 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE67185_RAW.tar |
228.4 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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