2XPK


Conserved Protein Domain Family
NAGidase
?
pfam07555: NAGidase (this model, PSSM-Id:336738 is obsolete and has been replaced by 429533)
Click on image for an interactive view with Cn3D
beta-N-acetylglucosaminidase
This family has previously been described as a hyaluronidase. However, more recently it has been shown that this family has beta-N-acetylglucosaminidase activity.
Links
?
Statistics
?
PSSM-Id: 336738
Aligned: 90 rows
Threshold Bit Score: 314.107
Created: 24-Mar-2017
Updated: 23-May-2017
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
2XPK_A        152 RGIVEGFYGTPWTHQDRLDQIKFYGENKLNTYIYAPKDDPYHREKWREPYPES-----------EM-----------QR- 208  Clostridium p...
Q8XK80        200 RGFIEGFYGVPWSHEDRMNLMKDTSEYKMNTYIYAPKDDPYHRLSWKELYPEQ-----------EA-----------KQ- 256  Clostridium p...
CCY35243      176 RGIVEGFYGHPYSVDNRISLFEFCKRFKMNVFIYGPKSDPYHLGNWRDNYPTS-----------LT-----------EQq 233  Tannerella sp...
CCX48784      170 RGLVEGFYGHPWSMESRLNILDHMMRYKMNYYVYGPKADPYHAGNWRVNYPETvtddqrklgqiTT-----------SD- 237  Bacteroides s...
CCY15468      179 RGLVEGYYGYPYTVAVKKDIMKFMARYKLNTYLYGAKSDPYHSGYYLDPYPTT-----------IT-----------EQq 236  Prevotella sp...
CDA45498      175 RGIIEGFYGKPYSSSVRKDLLRFMMRYKMNCYVYGPKSDPYHSGKWGEPYPTE-----------LTesqktsgfvcqQD- 242  Prevotella sp...
CDC24122      207 RGYIEGFYGA-WNFDERENLMEFAKDYKMNSYVYAPKGDAYHTSKWDQLYPDE-----------TI-----------KE- 262  Clostridium n...
WP_022601973  176 RGIVEGFYGYPYSVENRLSLLEYCKRYKMNLFVYGPKADPYHLGYWRRDYPTS-----------LTq----------AEq 234  Coprobacter f...
CCY51901      174 RGIVEGFYGHPYSTESRLNLLDYCKRYKMNMFVYGPKADPYHAGKWREDYPTT-----------ITd----------QEr 232  Bacteroides s...
WP_025278445  158 RGAIEGFYGNPYSVDAHCSLFEFFKRFKMNVFIYAPKMDPYHLGYWTEEYPTE-----------ITe----------EQr 216  Barnesiella v...

2XPK_A        209 ----------MQELINASAENKVDFVFGISP-----GIdirf-------dgdaG----EEDFNHLITKAESLYDMGVRSF 262  Clostridium p...
Q8XK80        257 ----------IAELAKAGAENNFNFCWTIHP-----GAtl-----------qfT----DEDFDALINKFEQLYSLGVRQF 306  Clostridium p...
CCY35243      234 kffglitqddLRRMVEAAKNCNVNFIWAAHP-----GLqqgi--------sfsNttemNKGIDALMTKFEHLHTLGVRGF 300  Tannerella sp...
CCX48784      238 ----------IQQLATHAAACKVDFVWAVHP-----TLgsy----------yiS----LYWVDDIMTKFQQLYSLGVRHF 288  Bacteroides s...
CCY15468      237 ekngwltqdmFKELTSTAHATKVSFIWAIHP-----GLnt------------kT----DQDVTDVMNKFKLMYDLGVRQF 295  Prevotella sp...
CDA45498      243 ----------LKDFTSVAADTKVSVVWAIHP-----GNai-----------mnS----ATVVDDVMKKFGSMYDLGFRQF 292  Prevotella sp...
CDC24122      263 ----------FEKLVKKAEETKVDFVWSIHL-----GNffksfs---sisdakY----ETQYQKLMAKLEQLYKIGVRKF 320  Clostridium n...
WP_022601973  235 eqgm-itqddLRTIAAKAQACNVNFVWAAHP-----AMqdgisf----ssesaM----DPGIEAIMNKFDHLYGLGVRGF 300  Coprobacter f...
CCY51901      233 hmgl-itqddLRELASKAKACNVAFIWSIHPaleggGInf-----------snL----DPGVEAIMEKFDHLHKLGIRHF 296  Bacteroides s...
WP_025278445  217 rmgw-itqddVRRMAETARACNVHFVWAAHP-----GLapggqvsmdfsntstV----DAGVELLMEKYHHMYDLGVRAF 286  Barnesiella v...

2XPK_A        263 AIYWDDIqd----kSAAKHAQVLNRFNEEFVKAKG--------Dv--------KPLITCPTEYDTGAmvsngqPR----- 317  Clostridium p...
Q8XK80        307 GVLFDDTdd---wrNGQKQAEWINKIDTEFVKAKG--------Dv--------APMIVISARYNSAWgp---nMD----- 359  Clostridium p...
CCY35243      301 GVFIDDMsy---tpSGNMQAHLANEVQIRLRNTYN--------Ntsdt-eehvSPLFFVPTAYALNY------GA----- 357  Tannerella sp...
CCX48784      289 GVSVDDMs-----gHPTNQAQLPDKVQQAIDEKWN--------TadaaeadcvGNVLFVPTCYALNY------GA----- 344  Bacteroides s...
CCY15468      296 GVFTDDAggydnpdNFPLYTQFFTNLQNQIDATWNtpgaapadTv--------KPLHYVPHVYNLTW------TSqdnrq 361  Prevotella sp...
CDA45498      293 AIFADDVnvpgdeaTMKKTADNVGAIQHAIEDKWNiagadpadTv--------KALRFTPQIYCRAF------AG----- 353  Prevotella sp...
CDC24122      321 DILNDDfg----ggNNDMVVTVLNRLNEDLKKKGC------------------QPITYCPQGYNKAWs-----GN----- 368  Clostridium n...
WP_022601973  301 GVFIDDIty---tpSGNMQAYLADQVQKKLKEKYN--------TvsatkdemvCPLFFVPTAYALNY------GG----- 358  Coprobacter f...
CCY51901      297 GVSIDDMs-----gHPYNQSDLADKAQVKLYEKFN--------KtgvseedkvGPLLFVPTQYALNY-------G----- 351  Bacteroides s...
WP_025278445  287 SVCIDDMdr---npSAQMQAHLPDQTQKRLKEEFP--------Sqaed--ekiAPLFYVPATYALMYs-----GA----- 343  Barnesiella v...

2XPK_A        318 A-----YTRIFAeTVDPSIEVMWTGPGVVtNEIPLSDAQ--LISGIYDRNMAVWWNYPVTDY--FKGKLAL--------- 379  Clostridium p...
Q8XK80        360 R-----YFKPFMqTLHDDIQVMWTGHATM-SNVSKEVFEwpKVQTGVDKDVAVWWNYPVNDY--CDSRILM--------- 422  Clostridium p...
CCY35243      358 S-----STLYDLkNVDSEVVIAFTGYDCF-SNIRPSSIT--DMSNRVGRNPVMWWNNPVNDD--HDDRIYM--------- 418  Tannerella sp...
CCX48784      345 T-----YSLTPIqEISSKVEVAFTGYDCF-SNVRASSFG--SMAEYIGRDPIFWWNNPVNDD--HDTWLYM--------- 405  Bacteroides s...
CCY15468      362 A-----YFKALs-EIPEKIVFYTTGYGVWt-VPNNNDLN--TMKNEFGRDVAWWWNYPCNDNgrSDSQIFP--------- 423  Prevotella sp...
CDA45498      354 PdsqfnSFFQAMsSLPANVTVYYTGGGVW-SVPNNNDLN--TLQTQFGRQAIWWWNYPCNDNgtGPSEIYPldmksnfvd 430  Prevotella sp...
CDC24122      369 G-----AELTALkNLNDDIHIYWTGDDVn-SPITQETVN--FLKEKTNHDPDFWLNYPVNEH--AKSGIYL--------- 429  Clostridium n...
WP_022601973  359 S-----YSLNSLkSVDSDVVIAFTGYDCF-SNIRGSSCA--DMAGRVGRNPVMWWNNPVNDD--HDERIYMrgvtah-wt 427  Coprobacter f...
CCY51901      352 T-----STLSSFkNIHKDVLVAFTGYDCF-SNIRGSACD--RMADLIGRNPIMWWNNPVNDD--YDEFLYMhgltar-wi 420  Bacteroides s...
WP_025278445  344 S-----SYLSQMaTVDKDVVIGFTGYAVC-GDLDKKDCD--AMAGYIGRNPLFWWNATVNDN--NDDRLYMreltahyal 413  Barnesiella v...

2XPK_A        380 ----GPMH------------GL-----DKGLNQyVDFFTVNPMEHAELSKISIHTAADYSWNMDNY--DYDKAWNRAIDM 436  Clostridium p...
Q8XK80        423 ----APLH------------NL-----NQDLDN-VSGFFSNPMNQAEASKVALYSIADYTWNTDAF--DYMKSWETSIEK 478  Clostridium p...
CCY35243      419 ----RKMT------------THwtiedPQGPINsLHGLVMNPMNQAQASKIALFGGADYGWNPSAF--DVEQNWEDVFER 480  Tannerella sp...
CCX48784      406 ----HGLT------------ARwt-ieQTGAVDhMRGFLLNPMNQGQVSKICNFSAADYSWNPDAY--NEQSSWEQALKS 466  Bacteroides s...
CCY15468      424 ----SDMYsnfidmtqvndnSR-----MPTSLEhCAGVLSNPMQQGEISKIALFSVADYAWNNDGF--DNMKSWEAAIPA 492  Prevotella sp...
CDA45498      431 mpnvGGGS------------I------ASELTAsNQGILCNPMEQGNASKTAIFSAGDYCWNNKGF--DNMKSWEASFKG 490  Prevotella sp...
CDC24122      430 ----GDIT------------YY-----ARDNVTgLAGFHSNPSRFAYSNEVGLYQLASLVWNNNKYseHANEIWESAFNY 488  Clostridium n...
WP_022601973  428 iedsEPIP------------S-------------LRGLMLNPMGQAQASKVALFGGADYAWNPARF--EKVSNWEASIRS 480  Coprobacter f...
CCY51901      421 iedkTPIS------------S-------------LQGLVLNPMNQGQVSKIALFSSADYAWNPAKF--DESASWEASLSS 473  Bacteroides s...
WP_025278445  414 vpetGGIS------------T-------------LGGVILNPEKQAQAAKVGLFGLADYCWNPDRF--DVSQNWYDCFDY 466  Barnesiella v...

2XPK_A        437 LYg----D--LAEDMKVF 448  Clostridium perfringens
Q8XK80        479 FVp----E--VKEEFMRF 490  Clostridium perfringens
CCY35243      481 LApn-dsQ--TATALKCF 495  Tannerella sp. CAG:118
CCX48784      467 IVkt--dE--NVKALKDF 480  Bacteroides sp. CAG:927
CCY15468      493 IIs---eD--YAPAFRTL 505  Prevotella sp. CAG:755
CDA45498      491 VLp---gNesAQKAYRFL 505  Prevotella sp. CAG:5226
CDC24122      489 Lq----pE--VKDSYLTI 500  Clostridium nexile CAG:348
WP_022601973  481 LVkd-deE--LRNAMRTF 495  Coprobacter fastidiosus
CCY51901      474 IVae--pE--LTEALKTF 487  Bacteroides sp. CAG:189
WP_025278445  467 LAeagdtE--TAEQIRLF 482  Barnesiella viscericola
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap