Conserved Protein Domain Family
Asp_protease_2
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pfam13650: Asp_protease_2 (this model, PSSM-Id:338873 is obsolete and has been replaced by 433378)
Aspartyl protease
This family consists of predicted aspartic proteases, typically from 180 to 230 amino acids in length, in MEROPS clan AA. This model describes the well-conserved 121-residue C-terminal region. The poorly conserved, variable length N-terminal region usually contains a predicted transmembrane helix.
Links
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Statistics
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PSSM-Id: 338873
Aligned: 153 rows
Threshold Bit Score: 39.5831
Created: 4-Apr-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
Download Cn3D
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q7MAZ2         54 VPVTI-SG---K-KY---QFLLDTGAS-YTFIDNKLAKTLTQTTPEsKIPVTFhrMLSDGL-VTTSEKRLH-Kadltlwq 122  Photorhabdus ...
Q1INV0        186 VSVDF-AG---T-AV---RANVDTGAGrGIVLPRSLQSKLPLEAAPvP-TESL--HTVSGE-QAASRAQLKgA------- 246  Candidatus Ko...
Q8ZYZ8          6 VKAKF-RG---KgEVvydEILVDTGAT-FTVLPLEVADKLIETP----FTVEL--KLGNGE-KVVAKVYVA-E------- 65   Pyrobaculum a...
Q9XX53        499 VPIRA-NG---M-PQ---SALIDTGAH-ITLASRSVCKILGISQLKsSKRINT--VGLGGNaVKLAGVASV-T------- 559  Caenorhabditi...
Q54AS8        247 AALLI-ND---K-NV---RGLVDTGSS-LTIIWESIAKKLNLKVEGkSF--SV--NSASNN-EIKIVGSCD-Ti------ 305  Dictyostelium...
Q7KWM0        149 ATLNI-FG---K-PI---KGLVDSGSL-LSILWSSVAKQLSLQVIPkR--VKF--TTAYGQ-EIYSTGSAE-A------- 206  Dictyostelium...
WP_012791203  137 LKGIL-NNn--K-TV---NVQFDLGAG-TTCVNRQVAEKLGLQFDGk---TVV--TNTQGT-NETGTSSGN-T------- 194  Chitinophaga ...
WP_012361505  100 VKLKH-NQi-eI-QT---TMLVDSGAE-VSLISYKMGQDLGYQLADaESTLVA--ETIGGN-VEYV-LRNV-E------- 160  Cyanothece
ABL78845        6 APVKLyHGeksL-EV---KALVDTGAT-TLVLPRSVAEELGLRVLGk---MDV--ELADGT-VKKVDYSIV-E------- 66   Thermofilum p...
XP_002488568  579 ITANI-LG---S-DV---RIMIDSGAT-GNYMDPRTQEKLQILGRKkPTPIPL--TGLNGE-KLSEEGITD-Etgw---- 641  Talaromyces s...

Q7MAZ2        123 plaITLGNHTVPSSDPWIGIdmslfnqsI-GQ-ELD-GILGIDT 163  Photorhabdus luminescens subsp. laumondii
Q1INV0        247 ---MKLGGYSIQGPQLDFVD-----------E-FPM-GNLGYPI 274  Candidatus Koribacter versatilis Ellin345
Q8ZYZ8         66 ---AEIEG-RRGPVRIVAFK----------G---AI-PVIGVDT 91   Pyrobaculum aerophilum
Q9XX53        560 ---FRIGK-KLIEHLVHFTEgrc---tpEaDR-SYS-FIFGNDI 594  Caenorhabditis elegans
Q54AS8        306 ---IKLGKASA-KVNVNIVK--------D-NDtSID-CIFGVDT 335  Dictyostelium discoideum AX4
Q7KWM0        207 ---IVSLGTAINNCEFIIVQ--------D-KV-LNDsCIFGLSV 237  Dictyostelium discoideum
WP_012791203  195 ---LTIGNISWEAVRLTQVGn-------M-QE-GED-LIIGNSL 225  Chitinophaga pinensis
WP_012361505  161 ---FTIDNHQLIAPVAWLQT--------L-TD-TEQ-SLLGREV 190  Cyanothece
ABL78845       67 ---VELSG-RRAPVLVAIVE-------------RGE-VCVGVEA 92   Thermofilum pendens Hrk 5
XP_002488568  642 -laMSIDG-HLEMINFDIAK--------L-G--RDD-VILGIPW 671  Talaromyces stipitatus ATCC 10500
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