Conserved Protein Domain Family
TMEM51

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pfam15345: TMEM51 
Transmembrane protein 51
This family of proteins is found in eukaryotes. Proteins in this family are typically between 233 and 253 amino acids in length.
Statistics
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PSSM-Id: 464663
Aligned: 14 rows
Threshold Bit Score: 265.045
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_016854182   6 SRGSHYALTAIGLGMLVLGVIMAVWNLVPGFGLA--SKP-HTAGNSSKTDPGAGKEQK----SKTFSVAYVLVGAGVFLL 78 
XP_002191849   6 ANGSHYALTAIGLGMLVLGIIMAVWNLVPGFGPP--DKPgSHAGNSSKPERGSGGILK----SKTFSVAYVLVGAGVLLL 79 
XP_003212362   6 TNGSHYALTAIGMGMLILGIILAVWNIVPGFGHP--DKP--NAGNSSKPDRGGGGIFK----SKTFSVAYVLVGAGLLLL 77 
XP_016277677   7 ANGSHYALTAIGLGMLVLGIIMAVWNLVPGFSHS--DKPlMHGNSSSP----GGSILK----SKTFSVAYVLVGAGIMLL 76 
XP_005994051   6 SSGSQYALSALGIGMLALGIIMMVWGVVPGINGIsgTKPqPQGNTSEI---DPGNEDRgfgkHKNSSVAYVLVGVGVGLL 82 
2_pfamImport   1 GSGAHYALCALGVGLIALGIVMIVWTVVPMDGEDsgATPtPPSNSTAGPDAKd--------sSQPSTVAMVLVGVGVAVL 72 
NP_001071198  18 NSGAQYATAALGVGLIALGIVMIVWSVVPA----------ASGGNSSKPGMNSGQVRE------TSSVAFVLVGGGVALL 81 
4_pfamImport   1 NSGSQYALCALGVGLVALGIVMIVWSVVPPDAA----------------GGDGSTSGRk---HKASSVAFVLVGSGVAML 61 
XP_003444926  36 NSGSQYALCALGVGLIALGIVMIVWSVVPATPV---------GNSSSS--GNQAGDSRk---NKASSVAFVLTGCGVAML 101
CAG07015       5 GSGAHYALCALGLGLIALGVVMIVWTVVPMDGEAssGSTtTPASNSSNP-GDGGDEVQkd-tTKSSTIAMVLVAVGAILL 82  spotted green p...
XP_016854182  79 LLSLCLGIRDRRKQRQD-EEGPRirhqvaretSSPSPQ-QDDSQEE---DDETLSRYYVPSYEEVVNADY--------PA 145
XP_002191849  80 LLSLCLNVRDKKRQSEDlAIAHV---------QHQVSTePSQQEDSqeeDEDVSSQYYVPSYEEVMNTGYse-----pRD 145
XP_003212362  78 LLSLCLNVRDKKRQS---EDIPRvvqh--qasVEPSQQ-EEDSQEE---DEDVSSRYYVPSYEEVMNAGY---------- 138
XP_016277677  77 LLSICLSIRDKRKQRQGeEEIARiqh---eaaVGTQTQeEEDSQEE----EESHSRYYVPSYEEVMNTNY---------- 139
XP_005994051  83 MLSICMSIRSKKRRRNDeETTNV---------QGETLHvASQDHQQedaQEDTASRYSAPSYDEVMRSDPssvdvgvfDQ 153
2_pfamImport  73 LLSILLCVRSRKKRGNAtSQPAA---------TADALLnHVAREPEe--AAADRASYTVPSYEEVVTSGAyp-----vRQ 136
NP_001071198  82 LLSVCLSVRNKQRAARGqEAGST----------------PSNTQEEgatMDQLAHSYTVPTYEEVVTSGQyp-----iSQ 140
4_pfamImport  62 LLSLCLGMRNKQREQQRlQE------------AQSRGGaATREQEErqtAEEQAQRYAVPSYEEAVCSGQyp-----iSQ 124
XP_003444926 102 LLSLCLGMRNKRREQ-RlQE------------AQNHSGaPGRDQEQretAEQQAQRYAVPTYEEAVCSGQyp-----vTQ 163
CAG07015      83 VLSISLGFRNKRRARARgNQ-TT---------AAVLLAsGLPERQEe--PAVDPAAFSVPSYDEVVGSGEfp-----vRQ 145 spotted green p...
XP_016854182 146 RTREdGGggaplSMSLPSYESLTGIDGDTPtrp-----------------gvSAPAAEGHPGIERQPSRHSSRLG---KR 205
XP_002191849 146 SDRSnRL-----SVSLPSYESLAGLEEGSA----------------------APGAAGGEPGPERPPSRHSSRLS---KR 195
XP_003212362 139 SEPHdPErnrriSVSLPSYESLTGLDEGTQ----------------------PPGAASAEPGTERPLGRHNSRLS---KR 193
XP_016277677 140 SETReLEqnpgmNMSLPSYESLTGLDETTP----------------------TTTRADTE---THPPDRQNSRLA---KR 191
XP_005994051 154 NN---RN-----STLLPSYESLVEGQGVAAsga-----------------nrQVATGSGEHP-----SRSNSRSG---RR 200
2_pfamImport 137 SNLR-NS-----TSQLPSYEDIIAAVENEGtgpadgas-----------------evtplghSLL--TRSASRAS---RL 188
NP_001071198 141 TSERhNS-----ITQLPAYEELEEGQNNLGdts-----------------sqARRSSSQIDPSTGAGPRRNSRPG---RK 195
4_pfamImport 125 SNLR-PS-----SSQLPSYDDLVQVDG-------------------------APPPAPAPLAPAAAASASNRRAGktsRK 173
XP_003444926 164 SSLR-PS-----ISQLPSYDDLVQVDGVQYenegse-----------gtvgrSQPAVDSSGPPAAAVSASNHRPGknnLK 226
CAG07015     146 SNLR-QS-----TSQLPSYEDIIAAVENEGadpaensrltgstkapaqaaaeppapgpapnASAP--ARSSSRAS---RL 214 spotted green p...
XP_016854182 206 LKPLKVRRIKSEKLHLKDLCVDLPAGHSAn-RVSIEPLTPPPQYE 249
XP_002191849 196 LKPLKVRRIKSEKLHLKDIRLNLEQGNSSsvPITIEPLTPPPKYE 240
XP_003212362 194 LKPLKVRRIKSEKLHLKDIRLNLGDGSSTg-PITIEPLTPPPKYE 237
XP_016277677 192 LKPLKVRRIKSEKLHLKDFRINLPEGNHP--PPTIEPLTPPPQYD 234
XP_005994051 201 LKPLKVRRIKSDKLHLKDFRLNTGEIKTQa-QISIEPLTPPPLYD 244
2_pfamImport 189 LRPLRVRRIKSDKLHLKDFRLQIRSPTQN--PVTIEPITPPPLYD 231
NP_001071198 196 LIPLKIRRIKSDNLRRKSL----SDIQQSn-VFTIEPLTPPPEYD 235
4_pfamImport 174 LLPIKIRRIKSEKLHMKN--LDNSQPATG---FSVEPLTPPPQYE 213
XP_003444926 227 LLPISIRRIKSEKLHMKN--IDNSQPTAG---FSIEPLTPPPQYE 266
CAG07015     215 LRPLRVRRIKSDKLHLKDFRLQIRSPTQN--PVTIEPITPPPQYD 257 spotted green pufferfish
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