Short-term mucosal disruption enables colibactin-producing E. coli to cause long-term perturbation of colonic homeostasis - - GEO DataSets

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Short-term mucosal disruption enables colibactin-producing E. coli to cause long-term perturbation of colonic homeostasis

(Submitter supplied) Colibactin, a bacterial genotoxin produced by E. coli harboring the pks genomic island, induces cytopathic effects such as DNA breaks, cell cycle arrest and apoptosis. Patients with a colonic dysfunction due to inflammatory bowel disease such as ulcerative colitis have an elevated likelihood of carrying pks+ E. coli in their colon microbiota but it is not clear whether and how they contribute to the pathogenesis of colitis. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL4134
4 Samples

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Accession:: GSE205403

ID:: 200205403

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