GEO DataSets for BioProject (Select 99215) - GEO DataSets

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Items: 2

Select item 2000068101.

Response of murine splenocytes to infection with wild type or virB mutant Brucella strains

(Submitter supplied) The virB operon, encoding a Type IV secretion system (T4SS), is essential for intracellular survival and persistent infection of Brucella spp. To better understand the role of the T4SS in evading host defense mechanisms and establishing chronic infection, we compared transcriptional profiles of the host response to infection with wild type Brucella strains and strains that fail to express the virB genes. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS2859
Platform:: GPL1261
10 Samples

Download data: CEL

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Accession:: GSE6810

ID:: 200006810

Select item 28592.

Splenocyte response to infection by virB mutant Brucella strains

Analysis of splenocytes from animals infected with virB mutant Brucella arbortus strains. The virB operon encodes a Type IV secretion system (T4SS) essential for the intracellular survival and persistent infection by Brucella species. Results provide insight into the role of T4SS in infections.