6W17


Conserved Protein Domain Family
P16-Arc

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pfam04699: P16-Arc 
ARP2/3 complex 16 kDa subunit (p16-Arc)
The Arp2/3 protein complex has been implicated in the control of actin polymerization. The human complex consists of seven subunits which include the actin related proteins Arp2 and Arp3, and five others referred to as p41-Arc, p34-Arc, p21-Arc, p20-Arc, and p16-Arc. The precise function of p16-Arc is currently unknown. Its structure consists of a single domain containing a bundle of seven alpha helices.
Statistics
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PSSM-Id: 461399
Aligned: 119 rows
Threshold Bit Score: 150.353
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6W17_G         3 FRTLDVDSITEPVLTEQDIFPirneTaE-QVQAAVSQLIPQARSAIQT---GNALQGLKTLLSYVPYGNDvQEVRTQYLN 78  Schizosaccharom...
XP_001892979  10 YRKLDVDAFDPEKFVDCEd----------AETPGIGPDERLVNQLLQS---AKLQEALKASLSNPPLKCKnQAIKDRSTA 76 
XP_002639570  10 YRKLDVDAFDPEQYDEND---------EtVDTPGLGPDERAVQGFLSS---NRLEDALHAALLSPPLKTKdQNVKDRATQ 77 
P91167         6 YKKYNVDIFHPAHFEDIQ-----------EESADCGPNVQEVRQFLES---NRLEYALQSVLLNPPFGHSeQELKNRAVL 71  Caenorhabditis ...
EFP11493       6 YRKYNVDDFDPAQFYDHH-----------DNLDGCGPDEEKVHQLLEA---NQLQDALKVSLLSPPLGHQeQALKDNSTL 71 
CDS38045      10 FRKLDVDSFSQSNFEEETVDD-------------THLNPRDVEGLLSS---GKYEEAVRMVLDNAPVNSKdAGLKDAVSA 73 
XP_018647725  10 FRTVNVDQLTEPTFQDELt----------EDIKPSRLNVSEINSLISS---GKSTDAILNILQNAPINSKdQQTKDTVFK 76 
XP_015789278   9 FRKIDIDSFNDDVFKEDDQVV--------SQSSGTSLDDKEILQLCSA---GKHYEAIKSIFDLQPQSSGdSAIKELAFN 77 
XP_002410106  10 FRKIDIDQYNEDNYKEDE-------ApDaQSNAQAGPDEQEVLDALTCvckGKNVDALKIILKAAPIGSKcQSVKDATSA 82 
XP_001950711  10 FRKIDVDQFNEN-FKEDEq--------PeNQSTTAIPDESEITTMINQ---GRFADALKSALKNAPLGSKnQQLRDNALN 77 
6W17_G        79 AFVDVLS-NIRAA-DIPAFVK----ECSTEEIDNIVNFIYRGLAnpqAYNSSV-LLNWHEKVVEISGIGCIVRVLNSRP 150 Schizosaccharomy...
XP_001892979  77 LVTKVLM-NIKTA-DIESVVK----SLTDDEVNLLMKFIYKAMDtqaDNATCQyLLLWHAQVLARGGYGAIIRVFCDRQ 149
XP_002639570  78 LVAKVLQ-SFKNA-EIEQAVQ----KLSIDEGDILMKYVYKAMElgsDAAACQsLLGWHAQLVSKFGHGAIMRVFSGRQ 150
P91167        72 LVAEVIH-AFRQT-DIEESVH----KLSNENGDILMKYIYKAMQlcsDSATCLsLLLWHSQLVSKFGQGSIVRVLSNRQ 144 Caenorhabditis e...
EFP11493      72 LVAHVLHySLKSS-DLVSIQEiidnQLSIDEADILMKYIYKAMQlssESSTCQsLLTWHSLLVAKFGHGAIVRVLAGRQ 149
CDS38045      74 LILRAMS-SIRSN-QVDAFVN----RLNQEQLDMLMKYIYRGFQkpvDITYPA-LLVWHEKALAKGKISSICRVLTDRQ 145
XP_018647725  77 LMMRLLS-QFKSNqNIDEFLS----TMDQDKIDLLMKYIYRGFEqpqEISCAA-LLTWHEKVYTYGKAGSIMRVLTDRK 149
XP_015789278  78 LIMQVFL-AVKTG-DIDRIVD----KLDTDQIDLLMKYVYKGFEspqEGSSSN-LLVWHDKIFRKSGHGAIVRVLTDKK 149
XP_002410106  83 LVMRVLL-AVKAS-EIEKAVG----SLDRDSVDVLMKYIYRGFEspsEGSSGH-LLAWHEKAYAAGGVGSIVRVMTDRK 154
XP_001950711  78 VVMKVLL-ATKLS-QIDEVVA----QLDVDMVDILMKYIYKGFEkstEKKSSH-LLMWHEKAYAIGGAGSIIRVLTDRK 149
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