Literature
PubMed
PubMed® comprises more than 37 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full text content from PubMed Central and publisher web sites.
Featured Bookshelf titles
Drug Therapy for Early Rheumatoid Arthritis
A Systematic Review Update
Literature databases
Books and reports
Ontology used for PubMed indexing
Books, journals and more in the NLM Collections
Scientific and medical abstracts/citations
Full-text journal articles
Data
Genes
Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution
Collected information about gene loci
Functional genomics studies
Gene expression and molecular abundance profiles
Homologous genes sets for selected organisms
Sequence sets from phylogenetic and population studies
Proteins
Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites
Conserved protein domains
Protein sequences grouped by identity
Protein sequences
Models representing homologous proteins with a common function
Experimentally-determined biomolecular structures
BLAST
A tool to find regions of similarity between biological sequences
Search nucleotide sequence databases
Search protein sequence databases
Search protein databases using a translated nucleotide query
Search translated nucleotide databases using a protein query
Find primers specific to your PCR template
Genomes
Genome sequence assemblies, large-scale functional genomics data, and source biological samples
Genome assembly information
Museum, herbaria, and other biorepository collections
Biological projects providing data to NCBI
Descriptions of biological source materials
Genome sequencing projects by organism
DNA and RNA sequences
High-throughput sequence reads
Taxonomic classification and nomenclature
Clinical
Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments
Privately and publicly funded clinical studies conducted around the world
Human variations of clinical significance
Genotype/phenotype interaction studies
Short genetic variations
Genome structural variation studies
Genetic testing registry
Medical genetics literature and links
Online mendelian inheritance in man
PubChem
Repository of chemical information, molecular pathways, and tools for bioactivity screening
Bioactivity screening studies
Chemical information with structures, information and links
Molecular pathways with links to genes, proteins and chemicals
Deposited substance and chemical information
News
Research news
Wild elephants may have names that other elephants use to call them
Forget names like "Dumbo"—wild elephants appear to have their own unique names that other elephants use while talking to them in low rumbles.
Pharmacists cite highest number of drug shortages since 2001
The Drug Information Service’s definition of a drug shortage is broader than the one used by the Food and Drug Administration.
Whooping cough cases double in the U.S., a potential legacy of the pandemic
Whooping cough cases have more than doubled so far in 2024, raising concerns for infants and older adults, the two groups at highest risk.
Recent blog posts
Insights into Molecular Basis of PTSD and Major Depression Could One Day Aid in Diagnosis and Treatment
We know stress can take a toll on our mental health. Yet, it’s unclear why some people develop stress-related mental health disorders and others don’t. The risk for developing a stress-related mental health disorder such as post-traumatic stress disorder (PTSD) or major depressive disorder (MDD) depends on a complex interplay between the genetic vulnerabilities we are born with and the impact of traumatic stress we experience over our lifetimes. Given this complexity, it’s been difficult for researchers to pinpoint the underlying biological pathways in the body that ultimately produce changes associated with PTSD, major depression, or other mental health conditions. Now, a study reported in a special issue of Science on decoding the brain uses a comprehensive approach to examine multiple biological processes across brain regions, cell types, and blood to elucidate this complexity. It’s an unprecedented effort to understand in a more holistic way the essential biological networks involved in PTSD and MDD.
MLA ‘24: Embracing the Future of Health Information Together
This year’s Medical Library Association annual conference, themed “Stronger Together,” gathered health information professionals from around the country for community and partnership. During the conference, NLM hosted an engaging AI Summit and discussed the role of AI in health sciences information… plus much more.
Study Suggests Computerized Brain Implant Could One Day Decode Internal Speech for Those Who Can No Longer Speak
The ability to communicate using only the thoughts in your mind might sound like the stuff of science fiction. But for people who’ve lost the ability to speak or move due to injury or disease, there’s now great hope that it may one day be possible using brain-computer interfaces (BCIs) that can “read” the relevant brain signals and translate them directly into written or spoken words. An NIH-supported team has now made an important but preliminary advance in this direction by showing for the first time that a computer can decode silent, internal speech with little training.