GEO DataSets

(Submitter supplied) Cnidarians are the only non-bilaterian group to evolve ciliated larvae with an apical sensory organ integrated with neurons, possibly homologous to the bilaterians. Within cnidarians, an apical organ with a ciliary tuft is identified only in sea anemones. Whether this apical tuft has evolved independently in anthozoans or alternatively originated in the eumetazoans and was lost independently in specific groups of cnidarians and bilaterians is uncertain.

Organism:

Aurelia aurita; Acropora millepora; Acropora tenuis; Nematostella vectensis

Type:

Expression profiling by high throughput sequencing

4 related Platforms

18 Samples

Download data: FASTA, TXT

(Submitter supplied) During early animal evolution, the emergence of axially-polarized segments was central to the diversification of complex bilaterian body plans. Nevertheless, precisely how and when segment polarity pathways arose remains obscure. Here we demonstrate the molecular basis for segment polarization in developing larvae of the pre-bilaterian sea anemone Nematostella vectensis. Utilizing spatial transcriptomics, we first constructed a 3-D gene expression atlas of developing larval segments. more...

Organism:

Nematostella vectensis

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL29226 GPL23029

31 Samples

Download data: CSV, H5

(Submitter supplied) Understanding how brains evolved is critical to determine the origin(s) of centralized nervous systems. Brains are patterned along their anteroposterior axis by stripes of gene expression that appear to be conserved, suggesting brains are homologous. However, the striped expression is also part of the deeply conserved anteroposterior axial program. An emerging hypothesis is that similarities in brain patterning are convergent, arising through the repeated co-option of axial programs. more...

Organism:

Nematostella vectensis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL29226

4 Samples

Download data: MTX, RDATA, TSV

(Submitter supplied) A diversity of life cycle stages processed into single-cell RNA-seq libraries in order to characterize cell type diversity and relationships

Organism:

Nematostella vectensis

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL23029 GPL29226

16 Samples

Download data: CSV, GTF, MTX, TSV

(Submitter supplied) The spatial transcriptome data has allowed us to explore the differential gene expression among the oral-aboral domains and provided new insights into the apical organ signalling pathways for future mechanistic studies and genes associated with oral/aboral differentiation. This resource identifies numerous candidates for elucidating the functional role of the apical organ and to address the evolution of the metazoan larval nervous system.

Organism:

Nematostella vectensis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL29226

10 Samples

Download data: TXT

(Submitter supplied) In mammals, the cGAS-cGAMP-STING pathway is crucial for sensing viral infection and initiating an anti-viral type I interferon response. cGAS and STING are highly conserved genes that originated in bacteria and are present in most animals. By contrast, interferons only emerged in vertebrates; thus, the function of STING in invertebrates is unclear. Here, we use the STING ligand 2'3'-cGAMP to activate immune responses in a model cnidarian invertebrate, the starlet sea anemone Nematostella vectensis. more...

Organism:

Nematostella vectensis

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL29855 GPL29226

33 Samples

Download data: TXT