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Items: 17

1.

Pharmacologic IRE1/XBP1s Activation Confers Targeted ER Proteostasis Reprogramming

(Submitter supplied) Activation of the IRE1/XBP1s signaling arm of the unfolded protein response (UPR) is a promising strategy to correct defects in endoplasmic reticulum (ER) proteostasis implicated in diverse diseases. However, no pharmacologic activators of this pathway identified to date are suitable for ER proteostasis remodeling through selective activation of IRE1/XBP1s signaling. Here, we use high-throughput screening to identify non-toxic compounds that induce ER proteostasis remodeling through IRE1/XBP1s activation. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL23227
15 Samples
Download data: XLSX
Series
Accession:
GSE148802
ID:
200148802
2.

BGISEQ-500 (Homo sapiens)

Platform
Accession:
GPL23227
ID:
100023227
3.

HEK293T_Tg-3

Organism:
Homo sapiens
Source name:
human embryonic kidney cells
Platform:
GPL23227
Series:
GSE148802
Download data
Sample
Accession:
GSM4481429
ID:
304481429
4.

HEK293T_Tg-2

Organism:
Homo sapiens
Source name:
human embryonic kidney cells
Platform:
GPL23227
Series:
GSE148802
Download data
Sample
Accession:
GSM4481428
ID:
304481428
5.

HEK293T_Tg-1

Organism:
Homo sapiens
Source name:
human embryonic kidney cells
Platform:
GPL23227
Series:
GSE148802
Download data
Sample
Accession:
GSM4481427
ID:
304481427
6.

HEK293T_IXA6-3

Organism:
Homo sapiens
Source name:
human embryonic kidney cells
Platform:
GPL23227
Series:
GSE148802
Download data
Sample
Accession:
GSM4481426
ID:
304481426
7.

HEK293T_IXA6-2

Organism:
Homo sapiens
Source name:
human embryonic kidney cells
Platform:
GPL23227
Series:
GSE148802
Download data
Sample
Accession:
GSM4481425
ID:
304481425
8.

HEK293T_IXA6-1

Organism:
Homo sapiens
Source name:
human embryonic kidney cells
Platform:
GPL23227
Series:
GSE148802
Download data
Sample
Accession:
GSM4481424
ID:
304481424
9.

HEK293T_IXA4-3

Organism:
Homo sapiens
Source name:
human embryonic kidney cells
Platform:
GPL23227
Series:
GSE148802
Download data
Sample
Accession:
GSM4481423
ID:
304481423
10.

HEK293T_IXA4-2

Organism:
Homo sapiens
Source name:
human embryonic kidney cells
Platform:
GPL23227
Series:
GSE148802
Download data
Sample
Accession:
GSM4481422
ID:
304481422
11.

HEK293T_IXA4-1

Organism:
Homo sapiens
Source name:
human embryonic kidney cells
Platform:
GPL23227
Series:
GSE148802
Download data
Sample
Accession:
GSM4481421
ID:
304481421
12.

HEK293T_IXA1-3

Organism:
Homo sapiens
Source name:
human embryonic kidney cells
Platform:
GPL23227
Series:
GSE148802
Download data
Sample
Accession:
GSM4481420
ID:
304481420
13.

HEK293T_IXA1-2

Organism:
Homo sapiens
Source name:
human embryonic kidney cells
Platform:
GPL23227
Series:
GSE148802
Download data
Sample
Accession:
GSM4481419
ID:
304481419
14.

HEK293T_IXA1-1

Organism:
Homo sapiens
Source name:
human embryonic kidney cells
Platform:
GPL23227
Series:
GSE148802
Download data
Sample
Accession:
GSM4481418
ID:
304481418
15.

HEK293T_DMSO-3

Organism:
Homo sapiens
Source name:
human embryonic kidney cells
Platform:
GPL23227
Series:
GSE148802
Download data
Sample
Accession:
GSM4481417
ID:
304481417
16.

HEK293T_DMSO-2

Organism:
Homo sapiens
Source name:
human embryonic kidney cells
Platform:
GPL23227
Series:
GSE148802
Download data
Sample
Accession:
GSM4481416
ID:
304481416
17.

HEK293T_DMSO-1

Organism:
Homo sapiens
Source name:
human embryonic kidney cells
Platform:
GPL23227
Series:
GSE148802
Download data
Sample
Accession:
GSM4481415
ID:
304481415
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Supplemental Content

db=gds|term=GSE148802[Accession]|query=1|qty=2|blobid=MCID_663ae6546390582feb57d076|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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