(Submitter supplied) The widely used chemical bisphenol A (BPA) has been associated with several health effects. In recent years, many derivatives were developed to replace BPA without thorough toxicological evaluation. Here, we employed a human embryoid body (EB)-based in vitro global differentiation and hepatic specification models, followed by RNA-seq analyses, to comprehensively study the potential developmental toxicity of six BPA replacements (BPS, BPF, BPZ, BPB, BPE, and BPAF), as compared to BPA.
more...- Organism:
- Homo sapiens
- Type:
- Expression profiling by high throughput sequencing
- Platform:
- GPL23227
- 18 Samples
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