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Items: 8

1.

EZH2 inhibition in multiple myeloma downregulates myeloma associated oncogenes and upregulates microRNAs with potential tumor suppressor functions [mRNA expression]

(Submitter supplied) Multiple Myeloma (MM) is a plasma cell tumor localized to the bone marrow (BM). Despite current progress in improving patient outcome, MM remains largely incurable. Disease clonal and interpatient heterogeneity has hampered identification of a common underlying mechanism for disease establishment and have slowed the development of novel targeted therapies. Epigenetic aberrations are now emerging as increasingly important in tumorigenesis, thus selective targeting of crucial epigenetic enzymes may provide new therapeutic potential in cancer including MM. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL17585
6 Samples
Download data: CEL
Series
Accession:
GSE87714
ID:
200087714

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [probe set (exon) version]

(Submitter supplied) See manufacturers website
Organism:
Homo sapiens
84 Series
3 Related Platforms
2415 Samples
Download data
Platform
Accession:
GPL17585
ID:
100017585

3.

INA-6 treated with EZH2 inhibitor UNC1999, biological repl 3

Organism:
Homo sapiens
Source name:
Mature Plasma cells
Platform:
GPL17585
Series:
GSE87714 GSE87716
Download data: CEL
Sample
Accession:
GSM2339218
ID:
302339218

4.

INA-6 treated with control UNC2400, biological repl 3

Organism:
Homo sapiens
Source name:
Mature Plasma cells
Platform:
GPL17585
Series:
GSE87714 GSE87716
Download data: CEL
Sample
Accession:
GSM2339217
ID:
302339217

5.

INA-6 treated with EZH2 inhibitor UNC1999, biological repl 2

Organism:
Homo sapiens
Source name:
Mature Plasma cells
Platform:
GPL17585
Series:
GSE87714 GSE87716
Download data: CEL
Sample
Accession:
GSM2339216
ID:
302339216

6.

INA-6 treated with control UNC2400, biological repl 2

Organism:
Homo sapiens
Source name:
Mature Plasma cells
Platform:
GPL17585
Series:
GSE87714 GSE87716
Download data: CEL
Sample
Accession:
GSM2339215
ID:
302339215

7.

INA-6 treated with EZH2 inhibitor UNC1999, biological repl 1

Organism:
Homo sapiens
Source name:
Mature Plasma cells
Platform:
GPL17585
Series:
GSE87714 GSE87716
Download data: CEL
Sample
Accession:
GSM2339214
ID:
302339214

8.

INA-6 treated with control UNC2400, biological repl 1

Organism:
Homo sapiens
Source name:
Mature Plasma cells
Platform:
GPL17585
Series:
GSE87714 GSE87716
Download data: CEL
Sample
Accession:
GSM2339213
ID:
302339213

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db=gds|term=GSE87714[Accession]|query=2|qty=2|blobid=MCID_665a91ce6c05354989585978|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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