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Items: 4

1.

Development of Progressive Aortic Vasculopathy in a Rat Model of Aging

(Submitter supplied) This study utilized a standard rat model of aging and global gene expression analyses to attempt to identify the most appropriate time points to study vascular aging and to identify molecules associated with the development of pathology. Recent studies have established that age is the major risk factor for vascular disease. Numerous changes occur in vascular structure and function during aging, and animal models, including rodents, are the primary means to determine the underlying mechanisms of age-mediated vascular pathology. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS3077
Platform:
GPL85
16 Samples
Download data: CEL, EXP
Series
Accession:
GSE7281
ID:
200007281
2.
Full record GDS3077

Age-related aortic vasculopathy model

Analysis of thoracic aortas (TAs) of Fischer 344/Brown Norway F1 hybrids (F344xBN) at 3 to 28 months of age. Age is a risk factor for vascular disease. The TAs of F344xBN animals exhibit age-related pathologies. Results provide insight into the mechanisms underlying age-mediated vascular pathology.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 4 age sets
Platform:
GPL85
Series:
GSE7281
16 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS3077
ID:
3077
3.

[RG_U34A] Affymetrix Rat Genome U34 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The RG-U34 set includes 3 arrays with a total of 26379 entries and was indexed 29-Jan-2002. more...
Organism:
Rattus norvegicus
98 DataSets
174 Series
1 Related Platform
3495 Samples
Download data
Platform
Accession:
GPL85
ID:
100000085
4.

Thoracic aorta age 15mo rep 2

Organism:
Rattus norvegicus
Source name:
Rat thoracic aorta at age 15 mo
Platform:
GPL85
Series:
GSE7281
Dataset:
GDS3077
Download data: CEL, EXP
Sample
Accession:
GSM175552
ID:
300175552
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