GSM189074[Accession] - GEO DataSets

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Items: 4

Select item 2000077931.

Vancomycin nephrotoxicity assessed by DNA microarray

(Submitter supplied) The glycopeptide antibiotic vancomycin (VCM) represents one of the last lines of defense against methicillin-resistant Staphylococcus aureus infections. However, vancomycin is nephrotoxic, but the mechanism of toxicity is still unclear. The goal of this study was twofold: (1) gain insights into the molecular mechanisms of vancomycin nephrotoxicity at the genomic level and (2) evaluate potential biomarkers (gene expression profiles) of vancomycin-induced kidney injury Keywords: Dose response

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS3435
Platform:: GPL1261
48 Samples

Download data: CEL, CHP

Series

Accession:: GSE7793

ID:: 200007793

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 34352.

Vancomycin effect on the kidney: dose response

Analysis of kidneys of BALB/c females treated with vancomycin (VA) for up to 400 mg/kg delivered intraperitoneally or intravenously. VA, an antibiotic treatment against methicillin-resistant Staphylococcus aureus, is nephrotoxic. Results provide insight into the molecular basis of VA nephrotoxicity.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent, 4 dose, 2 protocol sets

Platform:: GPL1261
Series:: GSE7793
48 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS3435

ID:: 3435

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000012613.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...