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Items: 3

1.

The isopeptidase inhibitor 2cPE triggers proteotoxic stress and ATM activation in chronic lymphocytic leukemia cells.

(Submitter supplied) In this study we investigated changes in gene expression induced by 2cPE (a non-selective isopeptidase inhibitor) in leukemia cells isolated from 10 different patients suffering of B-cell chronic lymphocytic leukemia. We compared 2cPE induced changes in mRNA levels with those induced by bortezomib, another well characterized proteasome inhibitor. Both inhibitors trigger apoptosis in leukemia cells.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL20650
26 Samples
Download data: CEL, TXT
Series
Accession:
GSE74514
ID:
200074514

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

[HG-U219_Hs_ENTREZG_18] Affymetrix Human Genome U219 Array [CDF: Brainarray HGU219_Hs_ENTREZG_v18]

(Submitter supplied) This identical to GPL13667 but a custom cdf environment was used to extract data. Protocol: see manufacturer's website
Organism:
Homo sapiens
4 Series
1 Related Platform
175 Samples
Download data
Platform
Accession:
GPL20650
ID:
100020650

3.

LLC366_2cPE

Organism:
Homo sapiens
Source name:
CLL cells - treated with 2cPE, patient LLC366
Platform:
GPL20650
Series:
GSE74514
Download data: CEL
Sample
Accession:
GSM1922023
ID:
301922023

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db=gds|term=GSM1922023[Accession]|query=2|qty=2|blobid=MCID_664e1cd3faf6612e8f1604ab|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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