GSM239312[Accession] - GEO DataSets

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Items: 4

Select item 2000094121.

Transcriptional regulation of aldo-keto reductase 1C1 in human colon cancer cells resistant to methotrexate

(Submitter supplied) The abstract of the associated publication (Selga E, Noé V, Ciudad CJ. Biochemical Pharmacology, 2008) is the following: While studying differentially expressed genes between sensitive and 10-5 M Methotrexate (MTX) resistant HT29 human colon cancer cells, we identified some members of the aldo-keto reductase (AKR) superfamily. The study was followed with the member AKR1C1 (EC 1.1.1.213), validating its increase in mRNA and protein levels in MTX resistant cells. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3160
Platform:: GPL571
6 Samples

Download data: CEL

Series

Accession:: GSE9412

ID:: 200009412

Select item 31602.

Methotrexate resistant colon cancer cell line

Analysis of HT29 derived colon cancer cells resistant to the anticancer drug methotrexate (MTX). Results provide insight into the molecular mechanisms contributing to MTX resistance.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 cell line sets

Platform:: GPL571
Series:: GSE9412
6 Samples

Download data: CEL

DataSet

Accession:: GDS3160

ID:: 3160

Select item 1000005713.

[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Human Genome U133A 2.0 Array is a single array representing 14,500 well-characterized human genes that can be used to explore human biology and disease processes. more...