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Items: 3

1.

Enhanced base editing by co-expression of free uracil DNA glycosylase inhibitor

(Submitter supplied) Even the latest generation of base editor (BE3) causes unwanted indels and non-C-to-T substitutions, compromising the fidelity of base editing outcome. Here we report a enhanced base editing system. The enhanced base edting system decreased the formation of unintended indels and C-to-A/C-to-G substitutions, and increased the frequency of desired C-to-T substitution, thereby improving both the accuracy and efficiency of base editing.
Organism:
Homo sapiens
Type:
Other
Platforms:
GPL20795 GPL16791 GPL18573
64 Samples
Download data: XLSX
Series
Accession:
GSE98685
ID:
200098685
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

HeLa_eBE-S3-2_2+HeLa_BE3_UGI-H-3_1+BE3-b_1+BE3-b_4

Organism:
Homo sapiens
Source name:
HeLa cells and 293FT cells
Platform:
GPL18573
Series:
GSE98685
Download data: XLSX
Sample
Accession:
GSM2743357
ID:
302743357
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