GSM550688[Accession] - GEO DataSets

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Items: 4

Select item 2000221391.

Bone morphogenetic protein-7 is a MYC target with pro-survival functions in childhood medulloblastoma

(Submitter supplied) Medulloblastoma (MB) is the most common malignant brain tumor in children, among whom overexpression or amplification of MYC oncogenes has been associated with poor clinical outcome. Although the MYC functions during normal development and oncogenesis in various systems have been extensively investigated, the transcriptional targets mediating MYC effects in MB are still elusive. Their identification and roles during MB onset and progression are important and will ultimately suggest novel potential therapeutic targets. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4466
Platform:: GPL570
18 Samples

Download data: CEL

Series

Accession:: GSE22139

ID:: 200022139

Select item 44662.

MYC oncogene overexpression and silencing effect in medulloblastoma DAOY cells

Analysis of medulloblastoma (MB)-derived cell lines genetically manipulated to either overexpress or silence the MYC oncogene. MYC overexpression and/or amplification is associated with poor clinical outcome. Results provide insight into transcriptional targets mediating the effects of MYC in MB.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 4 cell line, 5 protocol sets

Platform:: GPL570
Series:: GSE22139
18 Samples

Download data: CEL

DataSet

Accession:: GDS4466

ID:: 4466

Select item 1000005703.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...