GEO DataSets

(Submitter supplied) CD20 is a clinically validated target for Non-Hodgkin’s lymphomas and autoimmune diseases. Interactions of CD20 with the B cell receptor (BCR) and components of the BCR signaling cascade have been reported. In this study we show that antibodies against CD20 or activation of the BCR by specific antibodies induce very similar expression patterns of up- or down-regulated genes in NHL cell lines indicating that CD20 may play a role in BCR signaling and vice versa. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4982

Platform:

GPL570

96 Samples

Download data: CEL, XLS

Analysis of NHL lines treated with CD20 or B-cell receptor (BCR) antibodies. CD20 is a B cell-specific, cell surface protein; BCR has a key role in B cell development. Results provide insight into concordance in molecular changes following BCR activation and anti-CD20 Ab treatment in lymphoma cells.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 8 agent, 4 cell line sets

Platform:

GPL570

Series:

GSE23394

96 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...

Organism:

Homo sapiens

602 DataSets

5645 Series

61 Related Platforms

171173 Samples

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